158 results for "PKC alpha" in Products
PKC alpha Products
PKC alpha (Protein kinase C alpha) is an 80 kDa member of the PKC subfamily, AGC Ser/Thr protein kinase family of enzymes. It is widely expressed, and serves multiple cell-specific functions. PKC alpha is activated by increased diacylglycerol and intracellular calcium, and translocates to several sites such as the Golgi, nucleus and plasma membrane. Human PKC alpha is 672 amino acids (aa) in length. It contains two zinc finger regions (aa 36-151), a protein kinase domain (aa 339-557), and an AGC kinase region (aa 598-668). Phosphorylations on Thr497, Thr638 and Ser657 are necessary for kinase activity. Over aa 604-672, human PKC alpha shows 100% aa identity to mouse PKC alpha.
| Reactivity: | Human, Mouse, Rat, Porcine, Baboon, +8 More |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #MC5 |
| Applications: | IHC, WB, ELISA, Flow, ICC/IF, + 2 More |
Protein kinase C activator
| Alternate Names: | PMA |
| Chemical Name: | (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-(Acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-yl tetradecanoate |
| Purity: | ≥97% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, Simple Western |
Protein kinase C inhibitor
| Alternate Names: | Gö 6850,Bisindolylmaleimide I |
| Chemical Name: | 2-[1-(3-Dimethylaminopropyl)indol-3-yl]-3-(indol-3-yl) maleimide |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse, Rat, Porcine, Baboon, +8 More |
| Details: | Mouse IgG2A Monoclonal Clone #MC5 |
| Applications: | IHC, WB, ELISA, Flow, ICC/IF, + 2 More |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
Potent protein kinase C inhibitor; selective for α and β isozymes
| Chemical Name: | 5,6,7,13-Tetrahydro-13-methyl-5-oxo-12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propanenitrile |
| Purity: | ≥95% |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2F11 |
| Applications: | IHC, WB, ELISA, ICC/IF, Func |
Protein kinase inhibitor
| Alternate Names: | Bisindolylmaleimide IX |
| Chemical Name: | 3-[3-[2,5-Dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl]-1H-indol-1-yl]propyl carbamimidothioic acid ester mesylate |
| Purity: | ≥97% |
| Reactivity: | Human, Mouse |
| Details: | Rat IgG2B Monoclonal Clone #421810 |
| Applications: | WB |
Potent cdk inhibitor
| Chemical Name: | 3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #G13-R |
| Applications: | WB, ELISA, ICC/IF, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #M237 |
| Applications: | IHC, WB, ICC/IF, IP |
| Reactivity: | Human, Rat, Rabbit |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF, IP |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #S09-7C7 |
| Applications: | IHC, WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR2239 |
| Applications: | IHC, WB, ICC/IF, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #133 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #133 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |