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15 results for "Poly(ADP-ribose) Polymerase Inhibitors" in Products

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Poly(ADP-ribose) Polymerase Inhibitors

Poly (ADP-ribose) polymerase (PARP) catalyzes the post-translational modification of proteins by the addition of multiple ADP-ribose moieties. PARP transfers ADP-ribose from nicotinamide dinucleotide (NAD) to Glu/Asp residues on the substrate protein, and also polymerizes ADP-ribose to form long/branched chain polymers. Tankyrase proteins also display PARP activity.

PARP-1, one of 5 confirmed PARPs, is the most abundant and highly expressed PARP enzyme. PARP-1 detects and relocates to single ...

XAV 939

Catalog #: 3748

(1)

Alternate Names:	XAV939 Wnt Signaling Inhibitor
Chemical Name:	3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one
Purity:	≥98%

Chemical Name:	5'-Deoxy-5'-[4-[2-[(2,3-Dihydro-1-oxo-1H-isoindol-4-yl)amino]-2-oxoethyl]-1-piperazinyl]-5'-oxoadenosine dihydrochloride
Purity:	≥98%

Alternate Names:	AZD2281-BDY FL,Olaparib-BDY FL
Chemical Name:	(T-4)-[4-[[3-[[4-[3-[5-[(3,5-Dimethyl-2H-pyrrol-2-ylidene-κN)methyl]-1H-pyrrol-2-yl-κN-1-oxopropyl]-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinonato]difluoroboron
Purity:	≥90%

Chemical Name:	4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone
Purity:	≥98%

Chemical Name:	N-(5,6-Dihydro-6-oxo-2-phenanthridinyl)-2-acetamide hydrochloride
Purity:	≥98%

Chemical Name:	2-[3-[[4-(4-Methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]propyl]-1H-benz[de]isoquinoline-1,3(2H)-dione
Purity:	≥98%

Chemical Name:	4-[[4-Fluoro-3-[(4-methoxy-1-piperidinyl)carbonyl]phenyl]methyl]-1(2H)-phthalazinone
Purity:	≥98%

Alternate Names:	CO-338
Chemical Name:	8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2,ef][2]benzazepin-6-one (1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid
Purity:	≥98%

Chemical Name:	N-[2-Hydroxy-3-(1-piperidinyl)propoxy]-3-pyridinecarboximidamide dihydrochloride
Purity:	≥98%

Chemical Name:	N-[2-(9H-Carbazol-1-yl)phenyl]acetamide
Purity:	≥98%

Alternate Names:	ABT-888
Chemical Name:	2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-4-carboxamide dihydrochloride
Purity:	≥98%

Chemical Name:	3-(3-Butyn-1-yl)-N-[5-cyano-6-[4-[3-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]benzoyl]-1-piperazinyl]-3-pyridinyl]-3H-diazirine-3-propanamide
Purity:	≥95%

Poly(ADP-ribose) Polymerase Inhibitors

XAV 939

Nicotinamide

EB 47

PARPi-FL

Olaparib

PJ 34 hydrochloride

WIKI4

AZD 2461

Rucaparib camsylate

OUL 35

BGP 15

GeA-69

Veliparib dihydrochloride

PARPYnD

Nicotinamide