Key Product Details

Species Reactivity

Validated:

Human

Cited:

Boar

Applications

Validated:

Western Blot

Cited:

Immunohistochemistry

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all CD68/SR-D1 Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human CD68/SR‑D1
Asn22-Ile320
Accession # AAB25811

Specificity

Detects human CD68/SR‑D1 in direct ELISAs and Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human CD68/SR‑D1 Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Human CD68/SR-D1

Reviewed Applications

Read 1 review rated 5 using AF2040 in the following applications:

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: CD68/SR-D1

CD68, also called Scavenger Receptor D1 (SR-D1) or macrosialin in mouse, is a 110 kDa type I transmembrane glycoprotein that belongs to the LAMP family of molecules (1). It contains a 300 amino acid (aa) extracellular region that is rich in threonine and serine, a likely attachment site for multiple carbohydrates. Human CD68 shares 74% aa sequence identity to mouse CD68 in the extracellular region. CD68 is found on monocytes and macrophages and serves as a scavenger receptor for oxidized LDL.

References

  1. Holness, C.L. and D.L. Simmons (1993) Blood 81:1607.

Alternate Names

CD68, gp110, Macrosialin, SCARD1, SR-D1, SRD1

Entrez Gene IDs

968 (Human); 12514 (Mouse); 287435 (Rat)

Gene Symbol

CD68

UniProt

AAB25811

Additional CD68/SR-D1 Products

Product Documents for Human CD68/SR‑D1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human CD68/SR‑D1 Antibody

For research use only

Citations for Human CD68/SR‑D1 Antibody

Customer Reviews for Human CD68/SR‑D1 Antibody (1)

5 out of 5
1 Customer Rating
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  • Human CD68/SR-D1 Antibody
    Name: Anonymous
    Application: Immunohistochemistry-Paraffin
    Sample Tested: Liver
    Species: Human
    Verified Customer | Posted 04/15/2020
    Human CD68/SR‑D1 Antibody AF2040

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