Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all CREG Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human CREG
Arg32-Gln220
Accession # O75629

Specificity

Detects human CREG in direct ELISAs and Western blots. In Western blots, approximately 50% cross-reactivity with recombinant mouse CREG is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human CREG Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Human CREG

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: CREG

CREG is a secreted glycoprotein that belongs to the CREG protein family. It is induced during differentiation of pluripotent cells and is ubiquitously expressed in adult tissues. Mannose-6 phosphate (M6P) modified CREG binds directly to the M6P/IGF2 receptor to inhibit cell growth (1). Human and mouse CREG share approximately 77% amino acid sequence homology.

References

  1. DiBacco, A. and G. Gill (2003) Oncogene 22:5436.

Long Name

Cellular Repressor of E1A-stimulated Genes

Alternate Names

CREG1

Entrez Gene IDs

8804 (Human); 433375 (Mouse)

Gene Symbol

CREG1

UniProt

O75629

Additional CREG Products

Product Documents for Human CREG Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human CREG Antibody

For research use only

Citations for Human CREG Antibody

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