Human CXCL6/GCP-2 Antibody
Human CXCL6/GCP-2 Antibody Summary
Accession # P80162
Human CXCL6/GCP-2 Sandwich Immunoassay
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Chemotaxis Induced by CXCL6/GCP‑2 and Neutral-ization by Human CXCL6/ GCP‑2 Antibody. Recombinant Human CXCL6/ GCP-2 (Catalog # 333-GC) induces chemotaxis in the BaF3 mouse pro-B cell line transfected with human CXCR2 in a dose-dependent manner (orange line), as measured by Resazurin (Catalog # AR002). Under these conditions, chemotaxis elicited by CXCL6/GCP-2 is neutralized (green line) by increasing concentrations of Mouse Anti-Human CXCL6/GCP-2 Monoclonal Antibody (Catalog # MAB333). The ND50 is typically 8-30 µg/mL.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
CXCL6, also known as Granulocyte Chemotactic Protein 2 (GCP-2), belongs to the CXC chemokine family. It functions as a neutrophil chemoattractant through interactions with CXCR2.
Citations for Human CXCL6/GCP-2 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 2
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Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells
Authors: Kelvin K Tsai
J. Exp. Med., 2016-11-23;0(0):.
Sample Types: Whole Cells
GCP-2/CXCL6 synergizes with other endothelial cell-derived chemokines in neutrophil mobilization and is associated with angiogenesis in gastrointestinal tumors.
Authors: Penninckx F, Ectors N
Exp. Cell Res., 2005-02-15;303(2):331-42.
Sample Types: Recombinant Protein, Whole Tissue
Applications: IHC-P, Western Blot
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