Human Cytosolic Sulfotransferase 1B1/SULT1B1 Antibody

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Cytosolic Sulfotransferase 1B1/SULT1B1 in Human Liver.
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Human Cytosolic Sulfotransferase 1B1/SULT1B1 Antibody Summary

Species Reactivity
Detects human Cytosolic Sulfotransferase 1B1/SULT1B1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) SULT1A1, rhSULT1C1, or rhSULT1E1 is observed.
Monoclonal Mouse IgG1 Clone # 724429
Protein A or G purified from hybridoma culture supernatant
E. coli-derived recombinant human Cytosolic Sulfotransferase 1B1/SULT1B1
Accession # O43704
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
8-25 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunohistochemistry Cytosolic Sulfotransferase 1B1/SULT1B1 antibody in Human Liver by Immunohistochemistry (IHC-P). View Larger

Cytosolic Sulfotransferase 1B1/SULT1B1 in Human Liver. Cytosolic Sulfotransferase 1B1/SULT1B1 was detected in immersion fixed paraffin-embedded sections of human liver using Mouse Anti-Human Cytosolic Sulfotransferase 1B1/SULT1B1 Monoclonal Antibody (Catalog # MAB5959) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm of hepatocytes. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Sterile PBS to a final concentration of 0.5 mg/mL.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Cytosolic Sulfotransferase 1B1/SULT1B1

Cytosolic Sulfotransferases are a family of phase II drug-metabolizing enzymes that catalyze the sulfation of many endogenous and xenobiotic substrates (1‑3). They have important functions in the metabolism of many endogenous compounds including steroids, bile acids, thyroid hormones and monoamine neurotransmitters. They are distributed throughout the body and serve to inactivate and increase water-solubility of xenobiotics and therapeutic drugs. Cytosolic sulfotransferases are distinct from Golgi resident sulfotransferases by lacking N-terminal signal-anchorage domains and residing only in the cytoplasm. SULT1B1 is primarily expressed in the liver, peripheral blood leukocytes, colon, spleen and small intestine and can sulfate thyroid hormones and small phenols (4). Human SULT1B1 shares 72% amino acid sequence identity with mouse SULT1B1.

  1. Falany, C, N. (1997) FASEB J. 11:206.
  2. Gamage, N. U. et al. (2006) Toxicol. Sci. 90:5.
  3. Allali-Hassani, A. et al. (2007) PLoS Biol. 5:e97.
  4. Wang, J. et al. (1998) Mol. Pharmacol. 53:274.
Entrez Gene IDs
27284 (Human); 56362 (Mouse); 64305 (Rat)
Alternate Names
Cytosolic Sulfotransferase 1B1; EC 2.8.2; EC 2.8.2.-; EC; EC; MGC13356; ST1B1; ST1B2; ST1B2sulfotransferase family cytosolic 1B member 1; Sulfotransferase 1B1; Sulfotransferase 1B2; sulfotransferase family, cytosolic, 1B, member 1; SULT1B1; SULT1B2; Thyroid hormone sulfotransferase

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Isotype Controls

Reconstitution Buffers

Secondary Antibodies

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Human Cytosolic Sulfotransferase 1B1/SULT1B1 Antibody
By Anonymous on 02/20/2022
Application: IHC Sample Tested: Liver tissue Species: Human