Human GR/NR3C1 Antibody (Clone H8031)

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Human GR/NR3C1 Antibody (Clone H8031) Summary

Species Reactivity
Monoclonal Mouse IgG2a Clone # H8031
A liquid formulation in physiologic saline with 0.1% NaN3.


Recommended Concentration
Western Blot
Please refer to the PDF datasheet for specifications.
5-15 µg/mL
Perfusion fixed paraffin-embedded sections of rat pancreas
Please refer to the PDF datasheet for specifications.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: GR/NR3C1

Glucocorticoid receptor (GR; NR3C1) is a member of the steroid receptor family. GR are expressed in almost all human tissues and organs. GR bind to its sequences as a homodimer. Two different forms, GR-alpha and GR-beta, differing in their C-terminal parts were isolated. GR-alpha is the classic GR that binds to glucocorticoids and transactivates or transrepresses glucocorticoid-responsive promoters. GR-beta does not bind glucocorticoids.

Long Name
Glucocorticoid Receptor
Entrez Gene IDs
2908 (Human)
Alternate Names
GCR; glucocorticoid receptor; GR; GRGCCR; GRLNuclear receptor subfamily 3 group C member 1; NR3C1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); nuclear receptor subfamily 3, group C, member 1

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Human GR/NR3C1 Antibody (Clone H8031)
By Anonymous on 09/22/2021
Application: IHC IF Sample Tested: brain sections Species: Human