Human LILRB5/CD85c/LIR-8 Antibody Summary
Arg18-His456
Accession # O75023
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Example

Detection of LILRB5/CD85c/LIR-8 in Human peripheral blood monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Goat Anti-Human LILRB5/CD85c/LIR-8 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3065, filled histogram) or control antibody (Catalog # AB-108-C, open histogram), followed by Phycoerythrin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0107).
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: LILRB5/CD85c/LIR-8
Human LIR-8 (also known as CD85c and LILRB5) is a 587 amino acid transmembrane protein of the family of Leukocyte Immunoglobin-like Receptors. LIR-8 has a long N-terminus extracellular domain with four C2-type lg-like domains, and a short cytoplasmic tail with two immunoreceptor tyrosine-based inhibitory motifs (ITIMs) typically involved in modulation of cellular responses. Human LIR-8 is expressed in natural killer (NK) cells. There are at least two other known isoforms, one with 53 aa longer cytoplasmic domain, the other with a 100 aa deletion affecting one of the lg-like extracellular domains.
Product Datasheets
Citations for Human LILRB5/CD85c/LIR-8 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 4
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Coexpression of CD163 and CD141 identifies human circulating IL-10-producing dendritic cells (DC-10)
Authors: M Comi, D Avancini, F Santoni de, M Villa, MJ Uyeda, M Floris, D Tomasoni, A Bulfone, MG Roncarolo, S Gregori
Cell. Mol. Immunol., 2019;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
The extracellular interactome of the human adenovirus family reveals diverse strategies for immunomodulation
Nat Commun, 2016;7(0):11473.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
The Leukocyte Immunoglobulin-Like Receptor Family Member LILRB5 Binds to HLA-Class I Heavy Chains.
Authors: Zhang Z, Hatano H, Shaw J, Olde Nordkamp M, Jiang G, Li D, Kollnberger S
PLoS ONE, 2015;10(6):e0129063.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development.
Authors: Zheng J, Umikawa M, Cui C, Li J, Chen X, Zhang C, Hyunh H, Kang X, Silvany R, Wan X, Ye J, Canto AP, Chen SH, Wang HY, Ward ES, Zhang CC
Nature, 2012;485(7400):656-60.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
FAQs
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Reconstitution Buffers
Secondary Antibodies
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