Human/Mouse/Rat Lipin 2 Antibody
Human/Mouse/Rat Lipin 2 Antibody Summary
Accession # Q92539
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Lipin 2
Human Lipin 2 is a 100 kDa (896 aa) nuclear protein that belongs to the large, evolutionarily conserved Lipin family. All Lipin family members have a conserved N‑lipin domain at the N‑termini, a nuclear localization signal, and a conserved C-lipin domain near the C-termini. The functions of the N- and C-lipin domain are not known. Lipin 2 is widely expressed. Mutations in human Lipin 2 have been associated with autosomal dominant high grade myopia and Majeed syndrome. Over the region used as immunogen, human and mouse Lipin 2 are 100% identical. Lipin 2 also shares approximately 48% - 50% amino acid sequence identity with Lipin 1 and Lipin 3.
Citation for Human/Mouse/Rat Lipin 2 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
Dietary cholesterol reduces plasma triacylglycerol in apolipoprotein e-null mice: suppression of lipin-1 and -2 in the glycerol-3-phosphate pathway.
Authors: Obama T, Nagaoka S, Akagi K, Kato R, Horiuchi N, Horai Y, Aiuchi T, Arata S, Yamaguchi T, Watanabe M, Itabe H
PLoS ONE, 2011;6(8):e22917.
Sample Types: Cell Lysates
Applications: Western Blot
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