Human Porimin Antibody

R&D Systems | Catalog # AB3010

R&D Systems
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Flow Cytometry

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all Porimin Primary Antibodies »

Product Specifications

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human Porimin
His27-Ser149
Accession # AAG21694

Specificity

Detects human Porimin in direct ELISAs and Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human Porimin Antibody

Application
Recommended Usage

Flow Cytometry

0.25 µg/106 cells
Sample: Jurkat human acute T cell leukemia cell line

Western Blot

1 µg/mL
Sample: Recombinant Human Porimin

Flow Cytometry Panel Builder

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  • Antigen Density Selector - Match fluorochrome brightness with antigen density
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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Reconstitution

Reconstitute at 1 mg/mL in sterile PBS.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Porimin

Human Porimin is a 55‑110 kDa type I transmembrane (TM) glycoprotein that belongs to a mucin family. The ECD contains 45% serine and threonine and has multiple N- and O-linked glycosylation sites. The cytoplasmic tail contains a lysosome-targeting motif. Porimin activation induces cell death. The amino acid sequence of human Porimin ECD is 40% identical to that of mouse, rat and canine, respectively.

Long Name

Pro-Oncosis Receptor Inducing Membrane Injury

Alternate Names

KCT3, TMEM123

Entrez Gene IDs

114908 (Human)

Gene Symbol

TMEM123

UniProt

AAG21694

Additional Porimin Products

Product Documents for Human Porimin Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human Porimin Antibody

For research use only

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