Human Porimin Antibody

Catalog #: AB3010 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AB3010

Save 15% on Select RUO Reagents. See Details.

All Porimin Antibodies

Product Details

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human Porimin Antibody Summary

Species Reactivity

Human

Specificity

Detects human Porimin in direct ELISAs and Western blots.

Source

Polyclonal Goat IgG

Purification

Protein A or G purified

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human Porimin
His27-Ser149
Accession # AAG21694

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Human Porimin

Flow Cytometry

0.25 µg/10⁶ cells

Jurkat human acute T cell leukemia cell line

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 1 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Porimin

Human Porimin is a 55‑110 kDa type I transmembrane (TM) glycoprotein that belongs to a mucin family. The ECD contains 45% serine and threonine and has multiple N- and O-linked glycosylation sites. The cytoplasmic tail contains a lysosome-targeting motif. Porimin activation induces cell death. The amino acid sequence of human Porimin ECD is 40% identical to that of mouse, rat and canine, respectively.

Long Name

Pro-Oncosis Receptor Inducing Membrane Injury

Entrez Gene IDs

114908 (Human)

Alternate Names

KCT3; KCT-3; KCT3keratinocytes associated transmembrane protein 3; Keratinocytes-associated transmembrane protein 3; Porimin; PORIMINporimin; pro oncosis receptor inducing membrane injury; Pro-oncosis receptor inducing membrane injury; serine/threonine-rich receptor; TMEM123; transmembrane protein 123PORMIN