Q: I was wondering if you know of any blocking antibodies against IL-6 or VEGF-C that can be used in cell culture to quench these cytokines?

A: We have no antibodies that are currently known to show blocking antibodies to VEGF-C. Please see this link to our IL-6 antibodies with blocking/neutralizing activity can be found at this link.

Recombinant Rabbit IL-6 Protein

Novus Biologicals | Catalog # NBP3-11062

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Product Documents

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Product Specifications
Scientific Data
Preparation & Storage
Calculators
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Accession Number

Q9MZR1

Applications

Western Blot, ELISA

View all IL-6 Proteins and Enzymes »

Product Specifications

Description

Recombinant Rabbit Interleukin-6 (IL-6) is a recombinant protein corresponding to aa 27-214 of native rabbit IL-6.

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

24.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Rabbit IL-6 Protein

ELISA: Recombinant Rabbit IL-6 Protein [NBP3-11062]

ELISA: Recombinant Rabbit IL-6 Protein [NBP3-11062] - Recombinant Rabbit Interleukin-6 detected using Chicken anti Rabbit Interleukin-6 as the capture reagent and Chicken anti Rabbit Interleukin-6:Biotin as the detection reagent followed by Streptavidin:HRP.

Formulation, Preparation, and Storage

NBP3-11062

Preparation Method	Recombinant protein expressed in Pichia pastoris and purified by ion-exchange chromatography.
Formulation	PBS
Preservative	10% Trehalose
Concentration	Lyoph
Reconstitution	Reconstitute with 20 uL sterile PBS containing 0.1% carrier protein. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. We recommend that the vial is gently mixed after reconstitution.
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20C. Avoid freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background: IL-6

IL-6 is a multifunctional cytokine that has an important role in host defense by regulating immune and inflammatory responses. It is expressed by a variety of normal and transformed cells including T cells, B cells, monocytes/macrophages, fibroblasts and various tumor cells. IL-6 has diverse biological functions, it stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. Recombinant human IL-6 is a 20.9 kDa protein containing 184 amino acid residues. Human IL-6 is active on murine cells but murine IL-6 is inactive on human cells.

Long Name

Interleukin 6

Alternate Names

BSF-2, BSF2, IFNB2, IL6, MGI-2A

Gene Symbol

IL6

UniProt

Q9MZR1 (Rabbit)

Additional IL-6 Products

Product Documents for Recombinant Rabbit IL-6 Protein

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Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Recombinant Rabbit IL-6 Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Related Research Areas

Cancer Biomarkers

Conventional/Classical Dendritic Cells

Cytokines and Receptors in Allergy and Asthma

Cytokines and Receptors in Angiogenesis

Cytokines and Receptors Research

Diabetes

gamma delta T Cells

Glucose Homeostasis

Hypoxia Inducible Factors (HIFs)

IL-6 Family

Infectious Diseases

Inflammatory Mediators

Macrophage Activation Markers

Microglia Activation Markers

Myeloid-derived Suppressor Cells (MDSC)

Obesity

Plasmacytoid Dendritic Cells

T Cell Cytokine Signaling

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for Recombinant Rabbit IL-6 Protein

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Q: I was wondering if you know of any blocking antibodies against IL-6 or VEGF-C that can be used in cell culture to quench these cytokines?

A:
We have no antibodies that are currently known to show blocking antibodies to VEGF-C. Please see this link to our IL-6 antibodies with blocking/neutralizing activity can be found at this link.