Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all JMJD6/PSR Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse JMJD6/PSR
Ala289-Arg403
Accession # Q9ERI5

Specificity

Detects mouse JMJD6/PSR in direct ELISAs and Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Mouse JMJD6/PSR Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Mouse JMJD6/PSR

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: JMJD6/PSR

JMJD6 (Jumonji [Japanese for "cruciform/cross"] domain-containing protein 6; also PTDSR/PSR and Lysyl-hydroxylase JMJD6) is a 47-55 kDa member of the JMJD6 family, cupin superfamily of proteins. It is induced by hypoxia, and expressed in skeletal muscle, macrophages and possibly endothelial cells. JMJD6 is reported to demethylate histones (which it does not), serve as a phosphatidyl serine receptor (which it might), and act as a lysyl hydroxylase (which it does). In the nucleus, it appears to regulate pre-RNA splicing by hydroxylating various splicing factors such as U2AF65. Mouse JMJD6 is 403 amino acids (aa) in length. It contains five NLS's plus a JmjC domain (aa 141-305) and three iron-based catalytic sites. There at least three potential isoform variants. One contains a 29 aa substitution for aa 270‑403, a second possesses a 30 aa substitution for aa 302-314, and a third shows a 21 aa substitution for aa 315-403. JMJD6 is known to form high MW homo‑trimers, -tetramers and -oligomers. Full-length mouse JMJD6 shares 98% and 99% aa sequence identity with human and rat JMJD6, respectively.

Long Name

Jumonji Domain Containing 6/Phosphatidylserine Receptor

Alternate Names

PSR, PTDSR

Entrez Gene IDs

23210 (Human); 107817 (Mouse); 360665 (Rat)

Gene Symbol

JMJD6

UniProt

Q9ERI5

Additional JMJD6/PSR Products

Product Documents for Mouse JMJD6/PSR Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Mouse JMJD6/PSR Antibody

For research use only

Related Research Areas

Apoptosis
Redox Enzymes

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