Mouse Tryptase beta-1/MCP-7/Mcpt7 Antibody

Catalog # Availability Size / Price Qty
Product Details
Citations (5)
Supplemental Products

Mouse Tryptase beta-1/MCP-7/Mcpt7 Antibody Summary

Species Reactivity
Detects mouse Tryptase beta ‑1/MCP‑7/Mcpt7 in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross‑reactivity with recombinant human (rh) TPSB2 is observed, 5% cross-reactivity with rhTPS1 is observed, and less than 1% cross-reactivity with rhTPSG1 and recombinant mouse MCPT1 is observed.
Polyclonal Goat IgG
Antigen Affinity-purified
Mouse myeloma cell line NS0-derived recombinant mouse Tryptase beta ‑1/MCP‑7/Mcpt7
Accession # Q02844
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
Western Blot
0.1 µg/mL
Recombinant Mouse Tryptase  beta ‑1/MCP‑7/Mcpt7 (Catalog # 1937-SE)
25 µg/mL
Conditioned cell culture medium spiked with Recombinant Mouse Tryptase  beta ‑1/MCP‑7/Mcpt7 (Catalog # 1937-SE), see our available Western blot detection antibodies

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Tryptase beta-1/MCP-7

Tryptase beta -1 is a serine protease with trypsin-like activity, which is sometimes also referred to as Mast Cell Protease 7 (1). It is stored in the secretory granules of mouse mast cells (2). It exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of the diverse array of protease inhibitors in plasma (3). The deduced amino acid sequence for mouse Tryptase beta -1 consists of a signal peptide (residues 1‑18), a pro region (residues 19‑28) and the mature chain (residue 29‑273). The mature chain was expressed and purified.

  1. McNeil, H.P. et al. (1992) Proc. Natl. Acad. Sci. USA 89:11174.
  2. Matsumoto, R et al. (1995) J. Biol. Chem. 270:19524.
  3. Huang, C. et al. (1997) J. Biol. Chem. 272:31885.
Long Name
Mast Cell Protease 7
Entrez Gene IDs
100503895 (Mouse)
Alternate Names
Mast Cell Tryptase; Mcp7; MCP-7; Mcpt7; TPSB1; TRYB1; Tryptase beta1; Tryptase beta-1

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Citations for Mouse Tryptase beta-1/MCP-7/Mcpt7 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

5 Citations: Showing 1 - 5
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  1. Dendritic cell immunoreceptor drives atopic dermatitis by modulating oxidized CaMKII-involved mast cell activation
    Authors: X Luo, J Chen, H Yang, X Hu, MP Alphonse, Y Shen, Y Kawakami, X Zhou, W Tu, T Kawakami, M Wan, NK Archer, H Wang, P Gao
    JCI Insight, 2022;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  2. Immunotherapy using algal-produced Ara h 1 core domain suppresses peanut allergy in mice
    Authors: M Cecilia Berin
    Plant Biotechnol. J., 2016;14(7):1541-50.
    Species: Mouse
    Sample Types: Serum
    Applications: ELISA Development (Capture)
  3. Epidermal RAF prevents allergic skin disease
    Elife, 2016;5(0):.
  4. Blockade of mast cell activation reduces cutaneous scar formation.
    Authors: Chen L, Schrementi M, Ranzer M, Wilgus T, DiPietro L
    PLoS ONE, 2014;9(1):e85226.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  5. Phagocytosis-independent antimicrobial activity of mast cells by means of extracellular trap formation.
    Authors: von Kockritz-Blickwede M, Goldmann O, Thulin P, Heinemann K, Norrby-Teglund A, Rohde M, Medina E
    Blood, 2008;111(6):3070-80.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC


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