Mouse Tryptase beta-1/MCP-7/Mcpt7 Antibody
Mouse Tryptase beta-1/MCP-7/Mcpt7 Antibody Summary
Accession # Q02844
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Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Tryptase beta-1/MCP-7
Tryptase beta -1 is a serine protease with trypsin-like activity, which is sometimes also referred to as Mast Cell Protease 7 (1). It is stored in the secretory granules of mouse mast cells (2). It exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of the diverse array of protease inhibitors in plasma (3). The deduced amino acid sequence for mouse Tryptase beta -1 consists of a signal peptide (residues 1‑18), a pro region (residues 19‑28) and the mature chain (residue 29‑273). The mature chain was expressed and purified.
- McNeil, H.P. et al. (1992) Proc. Natl. Acad. Sci. USA 89:11174.
- Matsumoto, R et al. (1995) J. Biol. Chem. 270:19524.
- Huang, C. et al. (1997) J. Biol. Chem. 272:31885.
Citations for Mouse Tryptase beta-1/MCP-7/Mcpt7 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 5
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Dendritic cell immunoreceptor drives atopic dermatitis by modulating oxidized CaMKII-involved mast cell activation
Authors: X Luo, J Chen, H Yang, X Hu, MP Alphonse, Y Shen, Y Kawakami, X Zhou, W Tu, T Kawakami, M Wan, NK Archer, H Wang, P Gao
JCI Insight, 2022;0(0):.
Sample Types: Whole Tissue
Immunotherapy using algal-produced Ara h 1 core domain suppresses peanut allergy in mice
Authors: M Cecilia Berin
Plant Biotechnol. J., 2016;14(7):1541-50.
Sample Types: Serum
Applications: ELISA Development (Capture)
Epidermal RAF prevents allergic skin disease
Blockade of mast cell activation reduces cutaneous scar formation.
Authors: Chen L, Schrementi M, Ranzer M, Wilgus T, DiPietro L
PLoS ONE, 2014;9(1):e85226.
Sample Types: Tissue Homogenates
Applications: Western Blot
Phagocytosis-independent antimicrobial activity of mast cells by means of extracellular trap formation.
Authors: von Kockritz-Blickwede M, Goldmann O, Thulin P, Heinemann K, Norrby-Teglund A, Rohde M, Medina E
Sample Types: Whole Cells
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