428 results for "APP" in Products
APP Products
Amyloid Precursor Protein (APP) is a type I transmembrane protein that is ubiquitously expressed on cell surfaces. It undergoes complex proteolytic processing and is cleaved by alpha-, beta-, and gamma-Secretases to generate soluble APP alpha, soluble APP beta, and Amyloid beta (A beta) fragments of several lengths. One of these fragments, A beta 42, generated by beta- and gamma-Secretase activities, has been implicated in Alzheimer's disease. Aberrantly high levels of this peptide form and accumulate in the brains of Alzheimer's disease patients to create the senile plaques characteristic of the disease.
| Reactivity: | Human |
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Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse (Negative) |
| Details: | Rabbit IgG Kappa Monoclonal Clone #6E10 |
| Applications: | IHC, WB, ELISA, IP, MS |
![Western Blot: APP Antibody (6E10)ChimericAzide and BSA Free [NBP2-62566]](https://resources.rndsystems.com/images/products/APP-Antibody-6E10-Chimeric-Western-Blot-NBP2-62566-img0002.jpg "Western Blot: APP Antibody (6E10)ChimericAzide and BSA Free [NBP2-62566]")
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #304904 |
| Applications: | IHC, WB |
Brain penetrant fluorescent amyloid β probe. Used for: detection and quantification of plaques, tangles and cerebrovascular amyloid. Application: confocal microscopy, suitable for in vivo imaging
| Chemical Name: | 4,4'-[(2-methoxy-1,4-phenylene)di-(1E)-2,1-ethenediyl]bisphenol |
| Purity: | ≥98% |
Predominant amyloid β-protein fragment
| Purity: | ≥95% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF, DB |
![Western Blot: APP AntibodyBSA Free [NBP1-76910]](https://resources.rndsystems.com/images/products/APP-Antibody-Western-Blot-NBP1-76910-img0012.jpg "Western Blot: APP AntibodyBSA Free [NBP1-76910]")
| Reactivity: | Human |
| Source: | E. coli |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: APP Antibody [NBP2-15575]](https://resources.rndsystems.com/images/products/beta-Amyloid-Antibody-Western-Blot-NBP2-15575-img0008.jpg "Western Blot: APP Antibody [NBP2-15575]")
Inhibitor of Aβ42 fibril formation
| Chemical Name: | 2'-(4-Aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI7G9 |
| Applications: | IHC, WB, Flow, ICC/IF |
![Western Blot: APP Antibody (OTI7G9) [NBP2-02358]](https://resources.rndsystems.com/images/products/Amyloid-Precursor-Protein-Antibody-7G9-Western-Blot-NBP2-02358-img0002.jpg "Western Blot: APP Antibody (OTI7G9) [NBP2-02358]")
| Reactivity: | Human |
| Assay Range: | 0.625-20 ng/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI7G9 |
| Applications: | IHC, WB, Flow, ICC/IF, CyTOF-ready |
![Western Blot: APP Antibody (OTI7G9)Azide and BSA Free [NBP2-70187]](https://resources.rndsystems.com/images/products/APP-Antibody-OTI7G9-Azide-and-BSA-Free-Western-Blot-NBP2-70187-img0001.jpg "Western Blot: APP Antibody (OTI7G9)Azide and BSA Free [NBP2-70187]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![APP Antibody - BSA Free Immunohistochemistry: APP Antibody - BSA Free [NBP1-90246]](https://resources.rndsystems.com/images/products/nbp1-90246_rabbit-polyclonal-app-antibody-29520251632130.jpg "Immunohistochemistry: APP Antibody - BSA Free [NBP1-90246]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: APP Antibody [NBP1-32081]](https://resources.rndsystems.com/images/products/APP-Antibody-Western-Blot-NBP1-32081-img0008.jpg "Western Blot: APP Antibody [NBP1-32081]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #3A8S2 |
| Applications: | KO, WB, ELISA, ICC/IF, IP |
![Western Blot: APP Antibody (3A8S2) [NBP3-15560]](https://resources.rndsystems.com/images/products/APP-Antibody-3A8S2-Western-Blot-NBP3-15560-img0006.jpg "Western Blot: APP Antibody (3A8S2) [NBP3-15560]")
| Reactivity: | Human |
| Source: | NS0 |
| Accession #: | P05067 |
| Applications: | Inhibition Activity |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Mouse IgG Monoclonal Clone #MM32R |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG Monoclonal Clone #AB42-5 |
| Applications: | ELISA |
STAT3 activator; also protects against β-amyloid neurotoxicity
| Purity: | ≥95% |
Recombinant Monoclonal Antibody For Research Use Only
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Hu15 |
| Applications: | Flow, CyTOF-ready |
Recombinant Monoclonal Antibody For Research Use Only
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Hu13 |
| Applications: | Flow, CyTOF-ready |
Amyloid β-protein fragment
| Purity: | ≥95% |
