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14 results for "Cardiomyocyte Stem Cell Compounds Small Molecules and Peptides" in Products

Cardiomyocyte Stem Cell Compounds Small Molecules and Peptides

Cardiomyocyte Differentiation

Stem cell-derived cardiomyocytes have multiple potential uses in disease modeling and therapy. Signaling pathways important in the control of cardiomyocyte differentiation from pluripotent cells, include BMP, Wnt and TGF-β.

Two distinct methods have been developed for the differentiation of human pluripotent stem cells (hPSCs) into cardiomyocytes: the formation of embryoid bodies (EBs), and the culturing of hPSCs as a monolayer. The EB methodology involves ...

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Potent AMPK inhibitor; also BMP type I receptor inhibitor

Alternate Names: Compound C,BML-275
Chemical Name: 6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine dihydrochloride
Purity: ≥98%
Potent AMPK inhibitor; also BMP type I receptor inhibitor
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PORCN inhibitor; inhibits Wnt processing and secretion

Chemical Name: N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide
Purity: ≥98%
iPSC-derived heart organoids differentiated with IWP 2 and CHIR 99021
(2)
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Potent tankyrase inhibitor

GMP Version Available: TB3748-GMP
GMP
Alternate Names: XAV939 Wnt Signaling Inhibitor
Chemical Name: 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one
Purity: ≥98%
Potent tankyrase inhibitor
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TLR3 agonist

Chemical Name: Polyinosinic-polycytidylic acid sodium salt
Poly(I:C) | CAS No. 42424-50-0 | TLR3 agonist
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Highly potent PORCN inhibitor

Chemical Name: 4-(2-Methyl-4-pyridinyl)-N-[4-(3-pyridinyl)phenyl]benzeneacetamide
Purity: ≥99%
Highly potent PORCN inhibitor
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Thyroid hormone; also promotes differentiation of oligodendroglial precursor cells

Chemical Name: O-(4-Hydroxy-3-iodophenyl-3,5-diiodo-L-tyrosine
Purity: ≥98%
Thyroid hormone; also promotes differentiation of oligodendroglial precursor cells
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RARα agonist; anticancer agent

Alternate Names: Tamibarotene
Chemical Name: 4-[[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)amino]carbonyl]benzoic acid
Purity: ≥98%
RARα agonist; anticancer agent
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Neurogenic agent; induces neuronal differentiation of SVZ progenitors and also induces cardiomyogenic differentiation

Chemical Name: N-Cyclopropyl-5-(2-thienyl)-3-isoxazolecarboxamide
Purity: ≥98%
Neurogenic agent; induces neuronal differentiation of SVZ progenitors and also induces cardiomyogenic differentiation
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Potent and selective PDGFRβ inhibitor

Chemical Name: 5-[1,2-Dihydro-2-oxo-6-phenyl-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid
Purity: ≥98%
Potent and selective PDGFRβ inhibitor
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Inhibits canonical Wnt signaling. Promotes differentiation of human ESCs and iPSCs into cardiomyocytes

Chemical Name: N-(6-Chloro-2-benzothiazolyl)-3,4-dimethoxybenzenepropanamide
Purity: ≥98%
Inhibits canonical Wnt signaling. Promotes differentiation of human ESCs and iPSCs into cardiomyocytes
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Potent inhibitor of Wnt/β-catenin signaling

Chemical Name: N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3-(2-methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]-acetamide
Purity: ≥98%
Potent inhibitor of Wnt/β-catenin signaling
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DNA methyltransferase inhibitor

Chemical Name: 4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
Purity: ≥98%
DNA methyltransferase inhibitor
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Potent pan-JAK inhibitor; induces intermediate mesoderm; cell-permeable

Alternate Names: JAK inhibitor I
Chemical Name: 2-(1,1-Dimethylethyl)-9-fluoro-1,6-dihydro-7H-benz[h]imidazo[4,5-f]isoquinolin-7-one
Purity: ≥98%
Potent pan-JAK inhibitor; induces intermediate mesoderm; cell-permeable
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Estrogen-related receptor γ agonist; promotes maturation of hiPSC-derived cardiomyocytes

Chemical Name: 2-[2-(4-Bromophenyl)-1H-benzimidazol-6-yl]-2,3-dihydro-5-(4-morpholinyl)-1H-isoindol-1-one
Purity: ≥98%
Estrogen-related receptor γ agonist; promotes maturation of hiPSC-derived cardiomyocytes
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