14 results for "GluR4 Small Molecules and Peptides" in Products
GluR4 Small Molecules and Peptides
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamategated, caution-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA ...
Selective non-NMDA iGluR antagonist
| Chemical Name: | 6,7-Dinitroquinoxaline-2,3-dione |
| Purity: | ≥98% |
Potent AMPA antagonist; more selective than CNQX (Cat. No. 0190)
| Chemical Name: | 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide |
| Purity: | ≥98% |
Broad spectrum glutamatergic antagonist
| Chemical Name: | 4-Hydroxyquinoline-2-carboxylic acid |
| Purity: | ≥98% |
Positive allosteric modulator of AMPA receptors; inhibits AMPA desensitization
| Chemical Name: | 6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiazidiazine-7-sulfonamide-1,1-dioxide |
| Purity: | ≥98% |
Selective non-NMDA iGluR antagonist; water-soluble salt of DNQX (Cat. No. 0189)
| Chemical Name: | 6,7-Dinitroquinoxaline-2,3-dione disodium salt |
| Purity: | ≥98% |
Selective AMPA agonist
| Chemical Name: | (RS)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid |
| Purity: | ≥99% |
Selective non-competitive AMPA antagonist
| Chemical Name: | 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-benzenamine dihydrochloride |
| Purity: | ≥98% |
Open-channel blocker of AMPA currents; selective for non-GluA2-containing receptors
| Chemical Name: | N,N,H,-Trimethyl-5-[(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]-1-pentanaminiumbromide hydrobromide |
| Purity: | ≥98% |
Selective AMPA agonist; more water soluble form of (RS)-AMPA (Cat. No. 0169)
| Chemical Name: | (RS)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid hydrobromide |
| Purity: | ≥99% |
Competitive non-NMDA iGluR antagonist
| Alternate Names: | MPQX |
| Chemical Name: | [[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonic acid |
| Purity: | ≥98% |
GluK1 antagonist; inhibits carbonic anhydrase (CA) II and IV; also positive allosteric modulator of GABAA receptors
| Alternate Names: | Topamax |
| Chemical Name: | 2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate |
| Purity: | ≥98% |
Non-competitive non-NMDA iGluR antagonist
| Alternate Names: | GYKI 53773,LY 300164 |
| Chemical Name: | (8R)-7-Acetyl-5-(4-aminophenyl)-8,9-dihydro-8-methyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine |
| Purity: | ≥98% |
Selective positive allosteric modulator of AMPA receptors
| Chemical Name: | N-[2-(4'-Cyano[1,1'-biphenyl]-4-yl)propyl]-2-propanesulfonamide |
| Purity: | ≥98% |
Positive allosteric modulator of AMPA receptors
| Chemical Name: | N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide |
| Purity: | ≥98% |
