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179 results for "Jak2" in Products
Jak2 Products
Jak1, Jak 2, and Jak3 belong to the Janus Kinases family of protein tyrosine kinases that couple to cytokine receptors once activated by their corresponding ligands. Activation of Jak family members occurs via phosphorylation at two adjacent tyrosine residues as well as potentially one or more serine residues. Jaks activate members of the STAT family of transcription factors by phosphorylating critical tyrosine regulatory sites.
Jak1 is required for the activation of STAT1 and STAT2 in ...
| Chemical Name: | 1,4-Diamino-2,3-dicyano-1,4-bis[2-aminophenylthio]butadiene |
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| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #53B7 |
| Applications: | WB, ELISA, Flow, ICC/IF, Simple Western, + 1 More |
![Western Blot: Jak2 Antibody (53B7)BSA Free [NBP2-59451]](https://resources.rndsystems.com/images/products/Jak2-Antibody-53B7-Western-Blot-NBP2-59451-img0004.jpg "Western Blot: Jak2 Antibody (53B7)BSA Free [NBP2-59451]")
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| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #6-D3 |
| Applications: | IHC, WB, Flow, ICC/IF, MA |
![Western Blot: Jak2 Antibody (6-D3) [NBP2-66913]](https://resources.rndsystems.com/images/products/Jak2-Antibody-6-D3-Western-Blot-NBP2-66913-img0003.jpg "Western Blot: Jak2 Antibody (6-D3) [NBP2-66913]")
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SY24-03 |
| Applications: | IHC, WB, ICC/IF, IP |
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| Alternate Names: | Tofacitinib citrate |
| Chemical Name: | (3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidinepropanenitrile citrate |
| Purity: | ≥98% |
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| Alternate Names: | Tyrphostin AG 490 |
| Chemical Name: | (E)-2-Cyano-3-(3,4-dihydrophenyl)-N-(phenylmethyl)-2-propenamide |
| Purity: | ≥98% |
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| Reactivity: | Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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| Alternate Names: | CEP-701 |
| Chemical Name: | (9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one |
| Purity: | ≥98% |
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| Alternate Names: | INCB018424 |
| Chemical Name: | (3R)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile |
| Purity: | ≥98% |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR1129 |
| Applications: | IHC, WB, Flow, ICC/IF, IP |
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| Chemical Name: | (1R,5R,6R,7S)-rel-4-Oxo-8-(phenylmethyl)-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid 6,7-dimethyl ester |
| Purity: | ≥98% |
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| Alternate Names: | INCB 28050 |
| Chemical Name: | 1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile |
| Purity: | ≥98% |
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| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, IP |
![Western Blot: Jak2 Antibody [NBP1-22975]](https://resources.rndsystems.com/images/products/Jak2-Antibody-Western-Blot-NBP1-22975-img0004.jpg "Western Blot: Jak2 Antibody [NBP1-22975]")
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| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1A4 |
| Applications: | IHC, WB, ELISA, IP |
![Jak2 [p Tyr1007, p Tyr1008] Antibody (1A4)](https://resources.rndsystems.com/images/products/nbp3-26415_rabbit-jak2-p-tyr-1007-p-tyr-1008-mab-1a4-262202413221522.jpg "Immunoprecipitation: Jak2 [p Tyr1007, p Tyr1008] Antibody (1A4) [NBP3-26415] -")
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| Alternate Names: | JAK inhibitor I |
| Chemical Name: | 2-(1,1-Dimethylethyl)-9-fluoro-1,6-dihydro-7H-benz[h]imidazo[4,5-f]isoquinolin-7-one |
| Purity: | ≥98% |
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| Chemical Name: | (3R)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile phosphate |
| Purity: | ≥98% |
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| Chemical Name: | 4-((4-(1-(3-(Cyanomethyl)-1-(ethylsulfonyl)azetidin-3-yl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-N-(2-(4-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperazin-1-yl)ethyl)benzamide trifluoroacetate |
| Purity: | ≥98% |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
![Western Blot: Jak2 AntibodyBSA Free [NBP2-41310]](https://resources.rndsystems.com/images/products/Jak2-Antibody-Western-Blot-NBP2-41310-img0001.jpg "Western Blot: Jak2 AntibodyBSA Free [NBP2-41310]")
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| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: Jak2 Antibody [NBP2-55362]](https://resources.rndsystems.com/images/products/Jak2-Antibody-Western-Blot-NBP2-55362-img0002.jpg "Western Blot: Jak2 Antibody [NBP2-55362]")
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| Chemical Name: | 4-((4-(1-(3-(Cyanomethyl)-1-(ethylsulfonyl)azetidin-3-yl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-N-(3-(4-(4-(2,6-dioxopiperidin-3-yl)phenyl)piperazin-1-yl)propyl)benzamide |
| Purity: | ≥97% |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #OTI7D12 |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: Jak2 Antibody (OTI7D12) [NBP2-45468]](https://resources.rndsystems.com/images/products/Jak2-Antibody-7D12-Immunohistochemistry-NBP2-45468-img0001.jpg "Immunohistochemistry-Paraffin: Jak2 Antibody (OTI7D12) [NBP2-45468]")
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| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #OTI7D12 |
| Applications: | IHC |
![Immunohistochemistry: Jak2 Antibody (OTI7D12) - Azide and BSA Free [NBP2-71056]](https://resources.rndsystems.com/images/products/Jak2-Antibody-OTI7D12-Azide-and-BSA-Free-Immunohistochemistry-NBP2-71056-img0001.jpg "Immunohistochemistry: Jak2 Antibody (OTI7D12) - Azide and BSA Free [NBP2-71056]")
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| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Jak2 [p Tyr1007, p Tyr1008] Antibody [NBP3-13138]](https://resources.rndsystems.com/images/products/Jak2-[p-Tyr1007--p-Tyr1008]-Antibody-Western-Blot-NBP3-13138-img0002.jpg "Western Blot: Jak2 [p Tyr1007, p Tyr1008] Antibody [NBP3-13138]")
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| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #4B0K1 |
| Applications: | WB |
![Immunoprecipitation: Jak2 Antibody (4B0K1) [NBP3-15825]](https://resources.rndsystems.com/images/products/Jak2-Antibody-4B0K1-Immunoprecipitation-NBP3-15825-img0002.jpg "Immunoprecipitation: Jak2 Antibody (4B0K1) [NBP3-15825]")
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| Reactivity: | Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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