14 results for "RNA/DNA Polymerase Inhibitors Small Molecules and Peptides" in Products
RNA/DNA Polymerase Inhibitors Small Molecules and Peptides
RNA polymerases are categorized into two main groups: DNA-directed RNA polymerases (EC 2.7.7.6), commonly known as RNA polymerases or RNAP, which catalyze the synthesis of an RNA chain using a DNA template; and RNA-dependent RNA polymerases (EC 2.7.7.48), which catalyze the synthesis of an RNA chain from an RNA template.
In eukaryotes, fo...
Inhibits RNA polymerase
| Chemical Name: | 2-Amino-(N,N)-1-bis(hexadecahydro-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1]-[1,4,7,10,13] oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide |
| Purity: | ≥95% |
Inhibitor of DNA and RNA polymerase
| Chemical Name: | (1S)-5-Deoxy-1-C-[(2S,3S)-7-[[2,6-dideoxy-3-O-(2,6-dideoxy-β-D-arabino-hexopyranosyl)-β-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-β-D-ribo-hexopyranosyl-(1.fwdarw.3)-O-2,6-dideoxy-β-D-lyxo-hexopyranosyl-(1.fwdarw.3)-2,6-dideoxy-β-D-arabino-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-D-threo-2-pentulose |
| Purity: | ≥95% |
DNA polymerase α, δ and ε inhibitor
| Chemical Name: | (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-Tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-8,11a-methano-11aH-cyclohepta[a]naphthalene-4,9-dimethanol |
| Purity: | ≥98% |
Inhibitor of RNA polymerase II
| Chemical Name: | cyclo[L-Asparaginyl-4-hydroxy-L-prolyl-(R)-4,5-dihydroxy-L-isoleucyl-6-hydroxy-2-mercapto-L-tryptophylglycyl-L-isoleucylglycyl-L-cysteinyl]cyclic (4→8)-sulfide (R)-S-oxide |
| Purity: | ≥95% |
Reverse transcriptase inhibitor
| Alternate Names: | PMPA,(R)-9-(2-Phosphonoylmethoxypropyl)adenine |
| Chemical Name: | (R)-[[2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic acid |
| Purity: | ≥98% |
RNA polymerase inhibitor; inhibits replication of a broad range of RNA and DNA viruses, including SARS-CoV-2 and Zika
| Chemical Name: | (2S,3R,11bS)-3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolinyl]methyl]-2H-benzo[a]quinolizine dihydrochloride |
| Purity: | ≥98% |
RNA polymerase I inhibitor; also p53 pathway activator
| Chemical Name: | N-[2-(Dimethylamino)ethyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide |
| Purity: | ≥98% |
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide prodrug
| Alternate Names: | GS-5734 |
| Chemical Name: | 2-Ethylbutyl (2S)-2-[[(S)-[[(2R,3S,4R,5R)-5-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy]phenoxyphosphoryl]amino]propanoate |
| Purity: | ≥98% |
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleoside
| Chemical Name: | N-Hydroxycytidine |
| Purity: | ≥98% |
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide
| Chemical Name: | (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile |
| Purity: | ≥98% |
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral
| Alternate Names: | BCX 4430 |
| Chemical Name: | (2S,3S,4R,5R)-2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(hydroxymethyl)-3,4-pyrrolidinediol dihydrochloride |
| Purity: | ≥98% |
Viral RNA polymerase inhibitor
| Alternate Names: | T 705 |
| Chemical Name: | 6-Fluoro-3,4-dihydro-3-oxo-2-pyrazinecarboxamide |
| Purity: | ≥98% |
Potent and selective hepatitis B virus inhibitor
| Alternate Names: | BMS 200475,SQ 34676 |
| Chemical Name: | 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one |
| Purity: | ≥98% |
Non-nucleoside reverse transcriptase inhibitor
| Chemical Name: | 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile |
| Purity: | ≥98% |
