R&D Systems Range of Antibodies for G Protein-Coupled Receptors

G protein-coupled receptors (GPCRs) are the largest family of membrane receptors. As such, drug discovery has focused on this receptor family. Approximately 35% of all FDA-approved drugs target GPCRs. However, this represents only a small proportion of the 800 human GPCRs. This is due, in part, to orphan GPCRs still being understudied, as well as the heterogeneous nature of GPCRs, their endogenous ligands, and their binding sites. Efforts to elucidate the structure, biology, and therapeutic potential of non-targeted GPCRs is ongoing and continues to drive the development of GPCR-based therapeutics. R&D Systems offers a large selection of highly validated GPCR antibodies for supporting basic research and drug development.

The graphic below illustrates the number of antibodies we offer for different GPCR subfamilies. Click on the family names to explore the antibodies and other research tools available for the GPCRs in that family. To explore an expanded selection of antibodies for analyzing GPCRs and GPCR signaling, visit the GPCR page on the Novus Biologicals website.

Additionally, visit our Antibodies for G Protein-Coupled Receptors (GPCRs) page to learn about the challenges in GPCR antibody production and how R&D Systems overcomes these challenges to produce the highest performing GPCR antibodies in the industry.