Human C1qR1/CD93 Antibody Summary
Accession # Q9NPY3
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
C1qR1/CD93 in U937 Human Cell Line. C1qR1/CD93 was detected in immersion fixed U937 human histiocytic lymphoma cell line using Goat Anti-Human C1qR1/CD93 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2379) at 15 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. Staining was performed using our protocol for Fluorescent ICC Staining of Non-adherent Cells.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
C1q R1, also known as CD93, C1q R, and C1q RP, is a single chain glycoprotein expressed on cells of myeloid origin, endothelial cells, and hematopoietic progenitor cells. In vitro, this molecule may mediate the enhancement of phagocytosis upon interaction with soluble defense collagens (1, 2).
Kim, T.S. et al. (2000) Mol. Immunol. 37:377.
Dean, Y.D. and P. Gasque (2001) Eur. J. Immunol. 31:1370.
Citations for Human C1qR1/CD93 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 5
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Significance of Soluble CD93 in Type 2 Diabetes as a Biomarker for Diabetic Nephropathy: Integrated Results from Human and Rodent Studies
Authors: M Lee, HS Park, MY Choi, HZ Kim, SJ Moon, JY Ha, A Choi, YW Park, JS Park, EC Shin, CW Ahn, S Kang
J Clin Med, 2020;9(5):.
Sample Types: Serum
Applications: ELISA (detection)
Soluble CD93 is an apoptotic cell opsonin recognized by ?x ?2
Authors: JWD Blackburn, DHC Lau, EY Liu, J Ellins, AM Vrieze, EN Pawlak, JD Dikeakos, B Heit
Eur. J. Immunol., 2019;0(0):.
Sample Types: Whole Cells
Elevated expression of CD93 promotes angiogenesis and tumor growth in nasopharyngeal carcinoma
Authors: Lili Bao
Biochem Biophys Res Commun, 2016;0(0):.
Sample Types: Whole Tissue
Soluble CD93 levels in patients with acute myocardial infarction and its implication on clinical outcome.
Authors: Youn J, Yu H, Jeon J, Lee H, Jang Y, Park Y, Park Y, Shin E, Ha J
PLoS ONE, 2014;9(5):e96538.
Sample Types: Serum
Applications: ELISA Development (Detection)
Plasma CD93 concentration is a potential novel biomarker for coronary artery disease.
Authors: Malarstig A, Silveira A, Wagsater D, Ohrvik J, Backlund A, Samnegard A, Khademi M, Hellenius ML, Leander K, Olsson T, Uhlen M, de Faire U, Eriksson P, Hamsten A
J. Intern. Med., 2011;270(0):229-36.
Sample Types: Plasma
Applications: ELISA Development
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