Human ERR alpha 1/NR3B1 Antibody (Clone H5844)

Catalog # Availability Size / Price Qty
PP-H5844-00
Product Details
Citations (1)
FAQs
Supplemental Products
Reviews (1)

Human ERR alpha 1/NR3B1 Antibody (Clone H5844) Summary

Species Reactivity
Human
Source
Monoclonal Mouse IgG2a Clone # H5844
Formulation
A liquid formulation in physiologic saline with 0.1% NaN3.

Applications

Recommended Concentration
Sample
Western Blot
Please refer to the PDF datasheet for specifications.
Immunohistochemistry
5-15 µg/mL
Immersion fixed paraffin-embedded sections of human myocardium
Immunoprecipitation
Please refer to the PDF datasheet for specifications.
Direct ELISA
Please refer to the PDF datasheet for specifications.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: ERR alpha/NR3B1

Estrogen-related receptor alpha (ERR-alpha, ERR1, ESRL1; NR3B1) is a member of the orphan nuclear receptor family. ERR-alpha is expressed in the liver, kidney, brain, heart, uterus, vagina and cervix. ERR-alpha takes part in the cell cycle and the fatty acid metabolizing of the musculus skeleti. ERR-alpha was shown to interact with ER-alpha. ERR-beta (ERR2; NR3B2) is also expressed in the liver, brain, uterus, vagina, and cervix. ERR-beta has a role in early placental development. ERR-gamma (ESRRG; NR3B3) is expressed in the brain, kidney, testis, lung, adrenal gland, pancreas, placenta and bone marrow. ERR-gamma was shown to be located in the critical region for Ushers syndrome.

Long Name
Estrogen-related Receptor alpha
Entrez Gene IDs
2101 (Human)
Alternate Names
ERR alpha; ERR1; ERR1Estrogen receptor-like 1; ERRa; ESRL1; ESRL1ERR-alpha; ESRRA; estrogen-related receptor alphaERRalpha; NR3B1; NR3B1Nuclear receptor subfamily 3 group B member 1; steroid hormone receptor ERR1

Product Datasheets

Citation for Human ERR alpha 1/NR3B1 Antibody (Clone H5844)

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Activation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells.
    Authors: Spector NL, Yarden Y, Smith B, Lyass L, Trusk P, Pry K, Hill JE, Xia W, Seger R, Bacus SS
    Proc. Natl. Acad. Sci. U.S.A., 2007;104(25):10607-12.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot

FAQs

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Isotype Controls

Mouse IgG2A Isotype Control

Secondary Antibodies

Reviews for Human ERR alpha 1/NR3B1 Antibody (Clone H5844)

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Human ERR alpha 1/NR3B1 Antibody (Clone H5844)
By Anonymous on 07/27/2021
Application: WB Sample Tested: Liver tissue Species: Human