Human HIN-1/SCGB3A1 Antibody

Catalog # Availability Size / Price Qty
MAB27901
MAB27901-SP

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Product Details
Citations (1)
FAQs
Supplemental Products
Reviews (1)

Human HIN-1/SCGB3A1 Antibody Summary

Species Reactivity
Human
Specificity
Detects human HIN‑1/SCGB3A1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10% cross‑reactivity with recombinant mouse HIN-1 is observed.
Source
Monoclonal Mouse IgG1 Clone # 410219
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
E. coli-derived recombinant human HIN‑1/SCGB3A1
Phe21-Gly104
Accession # Q96QR1
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Human HIN-1/SCGB3A1
Immunocytochemistry
8-25 µg/mL
Immersion-fixed Y-79 human retinoblastoma cell line

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: HIN-1/SCGB3A1

High in Normal-1 (HIN-1), also known as Secretoglobulin 3A1 (SCGB3A1), PnSP-2, LuLeu-2, and UGRP-2 is an 8 kDa member of the Secretoglobulin family of molecules. It is synthesized as a 104 aa precursor that contains a 21 aa signal sequence and an 83 aa mature region. There are no potential N-linked glycosylation sites. Based on other members of the family, HIN-1 is likely to exist as a disulfide-linked homodimer. The molecule is found in mammary and upper airway epithelium. Mature mouse HIN-1 shares 60% aa sequence identity with mature human HIN-1.

Long Name
High in Normal 1
Entrez Gene IDs
92304 (Human); 73945 (Mouse)
Alternate Names
cytokine high in normal-1; Cytokine HIN-1; High in normal 1; HIN1; HIN-1; HIN1Pneumo secretory protein 2; LU105; PNSP2; PnSP-2; PnSP-2Uteroglobin-related protein 2; SCGB3A1; secretoglobin family 3A member 1; secretoglobin, family 3A, member 1; UGRP2; UGRP2MGC87867

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Citation for Human HIN-1/SCGB3A1 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Single-cell RNA sequencing reveals heterogeneous tumor and immune cell populations in early-stage lung adenocarcinomas harboring EGFR mutations
    Authors: D He, D Wang, P Lu, N Yang, Z Xue, X Zhu, P Zhang, G Fan
    Oncogene, 2020-11-03;0(0):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC

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Human HIN-1/SCGB3A1 Antibody
By avinash waghray on 02/26/2019
Application: Immunocytochemistry/Immunofluorescence Sample Tested: AIRWAYS Species: Human

Staining was done on human airways after citrate antigen retrieval. OCT sections were used