Human IFN‑ alpha Antibody

Name: Human IFN‑ alpha Antibody
Brand: R&D Systems
SKU: 21116-1
Price: 389 USD
Availability: InStock

R&D Systems | Catalog # 21116-1

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Product Documents

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas
Related Blogs

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Direct ELISA

Cited:

Neutralization, Blocking

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG₁ Clone # MMHA-13

View all IFN-alpha Primary Antibodies »

Product Specifications

Immunogen

Human Leukocyte Interferon

Specificity

Detects human interferon alpha in direct ELISAs.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Applications for Human IFN‑ alpha Antibody

Application

Recommended Usage

Direct ELISA

Binds to human interferon beta with high affinity.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Phosphate-buffered saline (PBS) containing 0.1% bovine serum albumin (BSA)

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

After receipt, the product may be stored at -20°C for short-term use ( ≤ 6 months). For long-term storage, we recommend storing the product at -70°C or below for retention of full activity. When thawing, the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum. Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the product should be in buffers containing protein such as 0.1% bovine serum albumin (BSA).

Background: IFN-alpha

Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.