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Human IL-8/CXCL8 DuoSet ELISA Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Sample Volume Required
100 µL
Assay Range
31.2 - 2,000 pg/mL
Sufficient Materials
For fifteen 96-well plates*
Specificity
Please see the product datasheet

* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.

This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant human CXCL8/IL-8. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.

Product Features

  • Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
  • Development protocols are provided to guide further assay optimization
  • Assay can be customized to your specific needs
  • Economical alternative to complete kits

Kit Content

  • Capture Antibody
  • Detection Antibody
  • Recombinant Standard
  • Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)

Other Reagents Required

DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.

The components listed above may be purchased separately:

PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered

Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4

Block Buffer: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered

Reagent Diluent: 0.1% BSA, 0.05% Tween 20 in Tris-buffered Saline (20 mM Trizma base, 150 mM NaCI) pH 7.2-7.4, 0.2 μm filtered

Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)

Stop Solution: 2 N H2SO4 (Catalog # DY994)

Microplates: R&D Systems (Catalog # DY990)

Plate Sealers: ELISA Plate Sealers (Catalog # DY992)

 

Data Example

Human IL-8 / CXCL8 ELISA Standard Curve

Product Datasheets

Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IL-8/CXCL8

Interleukin-8 (IL-8), also known as IL-8, GCP-1, and NAP-1, is a heparin-binding 8-9 kDa member of the alpha, or CXC family of chemokines. There are at least 15 human CXC family members that all adopt a three beta -sheet/one alpha -helix structure. Most CXC chemokines show an N-terminal Glu-Leu-Arg (ELR) tripeptide motif. IL-8 circulates as a monomer, homodimer, and heterodimer with CXCL4/PF4. The monomer is considered the most bio-active, while the heterodimer can potentiate PF4 activity. IL-8 oligomerization is modulated by its interactions with matrix and cell surface glycosaminoglycans (GAGs). Mature human IL-8 shares 65-69% amino acid (aa) identity with canine, feline, and porcine IL-8. There is no IL-8 gene counterpart in rodent. 


Multiple isoforms of IL-8 are generated through both alternative splicing and differential proteolytic cleavage. In humans, alternative splicing generates an iso-form with an eleven aa substitution at the C-terminus. Proteolytic processing results in N-terminal truncation of IL-8 and is likely a cell-specific event. For example, fibroblasts and endothelial cells generate the 1-77 form by cleaving IL-8 following Glu21, while monocytes and lymphocytes generate the 6-77 form by cleaving following Leu25. These truncated forms generally show increased bioactivity, particularly through the CXCR1 receptor. IL-8 can also undergo citrullination on Arg27 of the precursor, a modification that increases its half-life and ability to induce leukocytosis. A wide variety of cells secrete IL-8 including monocytes and neutrophils, fibroblasts and keratinocytes, mast cells, visceral smooth muscle cells, dendritic cells, type II great alveolar cells, and endothelial cells. 

IL-8 bioactivity is mediated through two G-protein-coupled receptors, termed CXCR1/IL-8 RA and CXCR2/IL-8 RB. CXCR1 is 45-50 kDa in size and is used almost exclusively by IL-8. CXCR2 is 35-40 kDa in size and is used by nearly all CXC chemokines. Both CXCR1 and CXCR2 constitutively associate into functional homodimers. They can also heterodimerize, but these complexes dissociate following IL-8 binding. CXCR2 responds to low concentrations of IL-8 and is principally associated with chemotaxis and MMP-9 release. CXCR1, in contrast, responds to high concentrations of IL-8 and is associated with respiratory burst and phospholipase D2 activation. Thus, CXCR2 ligation induces leukocyte adhesion to activated vascular endothelium and migration to sites of inflammation, while CXCR1 ligation primes neutrophil antimicrobial activity. IL-8 can also form a complex with Serpin A1/alpha-1 Antitrypsin, and this prevents IL-8 interaction with CXCR1. 

In addition to its pro-inflammatory effects, IL-8 is involved in angiogenesis and the pathogenesis of atherosclerosis and cancer. It induces VEGF expression in vascular endothelial cells and functions as an autocrine factor for EC growth and angiogenesis. It is upregulated in atherosclerotic lesions and is elevated in the serum and cerebrospinal fluid following myocardial infarction. In cancer, IL-8 promotes epithelial-mesenchymal transition as well as tumor cell invasiveness and metastasis.

Long Name:
Interleukin 8
Entrez Gene IDs:
3576 (Human); 396880 (Porcine); 403850 (Canine); 493836 (Feline)
Alternate Names:
3-10C; AMCF-I; C-X-C motif chemokine 8; CXCL8; CXCL8SCYB8; Emoctakin; GCP1; GCP-1TSG-1; IL8; IL-8; interleukin 8; K60; LAI; LECT; LUCT; LYNAP; MDNCF; MDNCFb-ENAP; member 8; MONAP; MONAPGCP1; NAF; NAP1; NAP-1NAP1; NCF; Neutrophil-activating protein 1; Protein 3-10C; T cell chemotactic factor; T-cell chemotactic factor; TCF; TSG1

Assay Procedure

GENERAL ELISA PROTOCOL

Plate Preparation

  1. Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.
  2. Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.
  3. Block plates by adding 300 μL of Block Buffer to each well. Incubate at room temperature for a minimum of 1 hour.
  4. Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.

Assay Procedure

  1. Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.
  2. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  3. Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.
  4. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  5. Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  6. Repeat the aspiration/wash as in step 2.
  7. Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  8. Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.
  9. Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.

Citations for Human IL-8/CXCL8 DuoSet ELISA

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

342 Citations: Showing 1 - 10
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  1. Influence of Periodontal Ligament Stem Cell-Derived Conditioned Medium on Osteoblasts
    Authors: S Novello, S Tricot-Dol, A Novella, P Pellen-Mus, S Jeanne
    Pharmaceutics, 2022;14(4):.
    Species: Human
    Sample Types: Cell Culture Supernates
  2. A novel Streptococcus pneumoniae human challenge model demonstrates Treg lymphocyte recruitment to the infection site
    Authors: G Szylar, R Wysoczansk, H Marshall, DJB Marks, R José, ME Ehrenstein, JS Brown
    Scientific Reports, 2022;12(1):3990.
    Species: Human
    Sample Types: Blister Fluid
  3. Flow cytometric single cell-based assay to simultaneously detect cell death, cell cycling, DNA content and cell senescence
    Authors: E Lieschke, Z Wang, C Chang, CE Weeden, GL Kelly, A Strasser
    Cell Death and Differentiation, 2022;0(0):.
    Species: Human
    Sample Types: Serum
  4. Transcriptional and DNA Methylation Signatures of Subcutaneous Adipose Tissue and Adipose-Derived Stem Cells in PCOS Women
    Authors: A Divoux, E Erdos, K Whytock, TF Osborne, SR Smith
    Cells, 2022;11(5):.
    Species: Human
    Sample Types: Cell Culture Supernates
  5. Echinococcus multilocularis specific antibody, systemic cytokine, and chemokine levels, as well as antigen-specific cellular responses in patients with progressive, stable, and cured alveolar echinococcosis: A 10-year follow-up
    Authors: B Grüner, L Peters, A Hillenbran, P Vo beta berg, J Schweiker, EG Rollmann, LH Rodriguez, J Blumhardt, S Burkert, P Kern, C Köhler, PT Soboslay
    PloS Neglected Tropical Diseases, 2022;16(2):e0010099.
    Species: Human
    Sample Types: Cell Culture Supernates
  6. MTMR14 Alleviates Chronic Obstructive Pulmonary Disease as a Regulator in Inflammation and Emphysema
    Authors: Y Gu, J Chen, Q Huang, Y Zhan, T Wang, J Wu, J Zhao, Z Zeng, Y Lv, C Xiao, J Xie
    Oxidative Medicine and Cellular Longevity, 2022;2022(0):9300269.
    Species: Human
    Sample Types: Cell Culture Supernates
  7. E-Cigarette Aerosols Promote Oral S. aureus Colonization by Delaying an Immune Response and Bacterial Clearing
    Authors: AR Cátala-Val, J Almeda, JN Bernard, AM Cole, AL Cole, SD Moore, CD Andl
    Cells, 2022;11(5):.
    Species: Human
    Sample Types: Cell Culture Supernates
  8. Mycobacterium avium-intracellulare complex promote release of pro-inflammatory enzymes matrix metalloproteinases by inducing neutrophil extracellular trap formation
    Authors: K Nakamura, H Nakayama, S Sasaki, K Takahashi, K Iwabuchi
    Scientific Reports, 2022;12(1):5181.
    Species: Human
    Sample Types: Cell Culture Supernates
  9. Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8
    Authors: T Walle, JA Kraske, B Liao, B Lenoir, C Timke, E von Bohlen, F Tran, P Griebel, D Albrecht, A Ahmed, M Suarez-Car, A Jiménez-Sá, T Beikert, A Tietz-Dahl, AN Menevse, G Schmidt, M Brom, JHW Pahl, W Antonopoul, M Miller, RL Perez, F Bestvater, NA Giese, P Beckhove, P Rosenstiel, D Jäger, O Strobel, D Pe'er, N Halama, J Debus, A Cerwenka, PE Huber
    Science Advances, 2022;8(12):eabh4050.
    Species: Human
    Sample Types: Serum
  10. In Vitro SARS-CoV-2 Infection of Microvascular Endothelial Cells: Effect on Pro-Inflammatory Cytokine and Chemokine Release
    Authors: M Dolci, L Signorini, S D'Alessand, F Perego, S Parapini, M Sommariva, D Taramelli, P Ferrante, N Basilico, S Delbue
    International Journal of Molecular Sciences, 2022;23(7):.
    Species: Human
    Sample Types: Cell Culture Supernates
  11. Repeated exposure of bronchial epithelial cells to particular matter increases allergen-induced cytokine release and permeability
    Authors: H Janbazacya, J van Bergen, S Varasteh, J Garssen, G Folkerts, S Braber
    Cytokine, 2022;154(0):155878.
    Species: Human
    Sample Types: Cell Culture Supernates
  12. Toxicological transcriptome of human airway constructs after exposure to indoor air particulate matter: In search of relevant pathways of moisture damage-associated health effects
    Authors: ME Nordberg, M Täubel, S Heikkinen, K Jalkanen, A Köliö, M Stranger, H Leppänen, A Hyvärinen, K Huttunen
    Environment international, 2022;158(0):106997.
    Species: Human
    Sample Types: Cell Culture Supernates
  13. DRP1-Mediated Mitochondrial Fission Regulates Lung Epithelial Response to Allergen
    Authors: SR Bruno, A Kumar, ZF Mark, R Chandrasek, E Nakada, N Chamberlai, B Mihavics, J Walzer, J Cahoon, AE Dixon, B Cunniff, V Anathy
    International Journal of Molecular Sciences, 2021;22(20):.
    Species: Human
    Sample Types: Cell Culture Supernates
  14. ARHGEF26 enhances Salmonella invasion and inflammation in cells and mice
    Authors: JS Bourgeois, L Wang, AF Rabino, J Everitt, MI Alvarez, S Awadia, ES Wittchen, R Garcia-Mat, DC Ko
    PloS Pathogens, 2021;17(7):e1009713.
    Species: Human
    Sample Types: Cell Culture Supernates
  15. Multi-level inhibition of coronavirus replication by chemical ER stress
    Authors: MS Shaban, C Müller, C Mayr-Buro, H Weiser, J Meier-Soel, BV Albert, A Weber, U Linne, T Hain, I Babayev, N Karl, N Hofmann, S Becker, S Herold, ML Schmitz, J Ziebuhr, M Kracht
    Nature Communications, 2021;12(1):5536.
    Species: Human
    Sample Types: Cell Culture Supernates
  16. Characterization of low-density granulocytes in COVID-19
    Authors: LE Cabrera, PT Pekkarinen, M Alander, KHA Nowlan, NA Nguyen, S Jokiranta, S Kuivanen, A Patjas, S Mero, SH Pakkanen, S Heinonen, A Kantele, O Vapalahti, E Kekäläinen, T Strandin
    PloS Pathogens, 2021;17(7):e1009721.
    Species: Human
    Sample Types: Serum
  17. Neutrophil function and bactericidal activity against Staphylococcus aureus after cardiac surgery with cardiopulmonary bypass
    Authors: M Lesouhaiti, M Gregoire, A Gacouin, V Coirier, A Frerou, C Piau, V Cattoir, E Dumontet, M Revest, P Tattevin, A Roisne, JP Verhoye, E Flecher, Y Le Tulzo, K Tarte, JM Tadié
    Journal of leukocyte biology, 2021;0(0):.
    Species: Human
    Sample Types: Plasma
  18. Development of a Human Intestinal Organoid Model for In Vitro Studies on Gut Inflammation and Fibrosis
    Authors: L Kandilogia, E Filidou, I Drygiannak, G Tarapatzi, S Didaskalou, M Koffa, K Arvanitidi, G Bamias, V Valatas, V Paspaliari, G Kolios
    Stem Cells International, 2021;2021(0):9929461.
    Species: Human
    Sample Types: Cell Culture Supernates
  19. Bioprintable Lung Extracellular Matrix Hydrogel Scaffolds for 3D Culture of Mesenchymal Stromal Cells
    Authors: B Falcones, H Sanz-Frail, E Marhuenda, I Mendizábal, I Cabrera-Ag, N Malandain, JJ Uriarte, I Almendros, D Navajas, DJ Weiss, R Farré, J Otero
    Polymers, 2021;13(14):.
    Species: Human
    Sample Types: Cell Culture Supernates
  20. IL-6 promotes drug resistance through formation of polyploid giant cancer cells and stromal fibroblast reprogramming
    Authors: N Niu, J Yao, RC Bast, AK Sood, J Liu
    Oncogenesis, 2021;10(9):65.
    Species: Human
    Sample Types: Cell Culture Supernates
  21. Neutrophils promote T-cell activation through the regulated release of CD44-bound Galectin-9 from the cell surface during HIV infection
    Authors: G Dunsmore, EP Rosero, S Shahbaz, DM Santer, J Jovel, P Lacy, S Houston, S Elahi
    PloS Biology, 2021;19(8):e3001387.
    Species: Human
    Sample Types: Plasma
  22. Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation
    Authors: N Jones, J Blagih, F Zani, A Rees, DG Hill, BJ Jenkins, CJ Bull, D Moreira, AIM Bantan, JG Cronin, D Avancini, GW Jones, DK Finlay, KH Vousden, EE Vincent, CA Thornton
    Nature Communications, 2021;12(1):1209.
    Species: Human
    Sample Types: Cell Culture Supernates
  23. The toxicity of Aspidosperma subincanum to MCF7 cells is related to modulation of oxidative status and proinflammatory pathways
    Authors: AF Santos, NSR Santos Mot, EM Schiefer, RS da Cunha, AM Junkert, AEM Stinghen, R Pontarolo, AR Crisma, AM Weffort-Sa, RC Pedrosa, WM de Souza, KB Felipe
    Journal of ethnopharmacology, 2021;0(0):114512.
    Species: Human
    Sample Types: Cell Culture Supernates
  24. Regulation of Cellular Senescence Is Independent from Profibrotic Fibroblast-Deposited ECM
    Authors: KEC Blokland, H Habibie, T Borghuis, GJ Teitsma, M Schuliga, BN Melgert, DA Knight, CA Brandsma, SD Pouwels, JK Burgess
    Cells, 2021;10(7):.
    Species: Human
    Sample Types: Cell Culture Supernates
  25. Plasma markers in pulmonary hypertension subgroups correlate with patient survival
    Authors: T Koudstaal, D van Uden, JAC van Hulst, P Heukels, IM Bergen, LW Geenen, VJM Baggen, AE van den Bo, LM van den To, PP Chandoesin, M Kool, E Boersma, RW Hendriks, KA Boomars
    Respiratory Research, 2021;22(1):137.
    Species: Human
    Sample Types: Plasma
  26. The ALPK1 pathway drives the inflammatory response to Campylobacter jejuni in human intestinal epithelial cells
    Authors: J Cui, C Duizer, LI Bouwman, KS van Rooije, CGP Voogdt, JPM van Putten, MR de Zoete
    PloS Pathogens, 2021;17(8):e1009787.
    Species: Human
    Sample Types: Cell Culture Supernates
  27. Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1alpha kinase inhibitor KIRA6 through HSP60 targeting
    Authors: N Rufo, D Korovesis, S Van Eygen, R Derua, AD Garg, F Finotello, M Vara-Perez, J Rožanc, M Dewaele, PA de Witte, LG Alexopoulo, S Janssens, L Sinkkonen, T Sauter, SHL Verhelst, P Agostinis
    Cell Death and Differentiation, 2021;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  28. Mimicking of Blood Flow Results in a Distinct Functional Phenotype in Human Non-Adherent Classical Monocytes
    Authors: E Wirthgen, M Hornschuh, IM Wrobel, C Manteuffel, J Däbritz
    Biology, 2021;10(8):.
    Species: Human
    Sample Types: Cell Culture Supernates
  29. Bacterial genotoxins induce T�cell senescence
    Authors: SL Mathiasen, L Gall-Mas, IS Pateras, SDP Theodorou, MRJ Namini, MB Hansen, OCB Martin, CK Vadivel, K Ntostoglou, D Butter, M Givskov, C Geisler, AN Akbar, VG Gorgoulis, T Frisan, N Ødum, T Krejsgaard
    Cell Reports, 2021;35(10):109220.
    Species: Human
    Sample Types: Cell Culture Supernates
  30. Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response
    Authors: M Sueiro-Oli, J Scott, S Gago, D Petrovic, E Kouroussis, J Zivanovic, Y Yu, M Strobel, C Cunha, D Thomson, R Fortune-Gr, S Thusek, P Bowyer, A Beilhack, A Carvalho, E Bignell, MR Filipovic, J Amich
    PloS Biology, 2021;19(6):e3001247.
    Species: Human
    Sample Types: Cell Culture Supernates
  31. Identification of monoclonal antibodies against human renal glomerular endothelial cells in lupus nephritis that induce endothelial interferon-alpha production
    Authors: YC Hu, IJ Tsai, HY Hsu, BL Chiang, YH Yang
    Arthritis Research & Therapy, 2021;23(1):171.
    Species: Human
    Sample Types: Cell Culture Supernates
  32. Pseudomonas aeruginosa induces p38MAP kinase-dependent IL-6 and CXCL8 release from bronchial epithelial cells via a Syk kinase pathway
    Authors: MS Coates, EWFW Alton, GW Rapeport, JC Davies, K Ito
    PLoS ONE, 2021;16(2):e0246050.
    Species: Human
    Sample Types: Cell Culture Supernates
  33. The Polymethoxy Flavonoid Sudachitin Inhibits Interleukin-1&beta-Induced Inflammatory Mediator Production in Human Periodontal Ligament Cells
    Authors: Y Hosokawa, I Hosokawa, K Ozaki, T Matsuo
    BioMed Research International, 2021;2021(0):8826586.
    Species: Human
    Sample Types: Cell Culture Supernates
  34. Synergistic cycles of protease activity and inflammation via PPAR&gamma degradation in chronic obstructive pulmonary disease
    Authors: N Kwak, KH Lee, J Woo, J Kim, CH Lee, CG Yoo
    Experimental & Molecular Medicine, 2021;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  35. Production of IL-1&beta, IL-6 and CXCL8 by endometrium of crossbred heifers stimulated with various pathogen-associated molecular patterns
    Authors: PP Nunes, TDM Martins, AC Leite, EBM Silva, TA da Paixão, RL Santos, ÁM Borges
    Animal reproduction science, 2021;228(0):106736.
    Species: Bovine
    Sample Types: Cell Culture Supernates
  36. Impairment in inflammasome signaling by the chronic Pseudomonas aeruginosa isolates from cystic fibrosis patients results in an increase in inflammatory response
    Authors: MS Phuong, RE Hernandez, DJ Wolter, LR Hoffman, S Sad
    Cell Death & Disease, 2021;12(3):241.
    Species: Human
    Sample Types: Cell Culture Supernates
  37. Palladin isoforms 3 and 4 regulate cancer-associated fibroblast pro-tumor functions in pancreatic ductal adenocarcinoma
    Authors: JI Alexander, DB Vendramini, R Francescon, T Luong, J Franco-Bar, N Shah, JC Gardiner, E Nicolas, KS Raghavan, E Cukierman
    Scientific Reports, 2021;11(1):3802.
    Species: Human
    Sample Types: Cell Culture Supernates
  38. Polymicrobial stimulation of human fetal membranes induce neutrophil activation and neutrophil extracellular trap release
    Authors: M Tong, SE Hanna, VM Abrahams
    Journal of reproductive immunology, 2021;145(0):103306.
    Species: Human
    Sample Types: Cell Culture Supernates
  39. Increase of aerobic glycolysis mediated by activated T helper cells drives synovial fibroblasts towards an inflammatory phenotype: new targets for therapy?
    Authors: P Kvacskay, N Yao, JH Schnotz, R Scarpone, RA Carvalho, KD Klika, W Merkt, T Tretter, HM Lorenz, LO Tykocinski
    Arthritis Research & Therapy, 2021;23(1):56.
    Species: Human
    Sample Types: Cell Culture Supernates
  40. PHAIR: a biosensor for pH measurement in air-liquid interface cell culture
    Authors: M Dabaghi, N Saraei, G Xu, A Chandiramo, J Yeung, JP Nguyen, M Vukmirovic, PR Selvaganap, JA Hirota
    Scientific Reports, 2021;11(1):3477.
    Species: Human
    Sample Types: Cell Culture Supernates
  41. An inverted in vitro triple culture model of the healthy and inflamed intestine: Adverse effects of polyethylene particles
    Authors: M Busch, AAM Kämpfer, RPF Schins
    Chemosphere, 2021;284(0):131345.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  42. Early bilirubinemia after allogeneic stem cell transplantation-an endothelial complication
    Authors: H Dai, O Penack, A Radujkovic, D Schult, J Majer-Laut, IW Blau, L Bullinger, S Jiang, C Müller-Tid, P Dreger, T Luft
    Bone marrow transplantation, 2021;0(0):.
    Species: Human
    Sample Types: Serum
  43. Triple co-culture and perfusion bioreactor for studying the interaction between Neisseria gonorrhoeae and neutrophils: A novel 3D tissue model for bacterial infection and immunity
    Authors: M Heydarian, M Schweinlin, T Schwarz, R Rawal, H Walles, M Metzger, T Rudel, V Kozjak-Pav
    Journal of tissue engineering, 2021;12(0):2041731420988.
    Species: Human
    Sample Types: Cell Culture Supernates
  44. Interleukin-8 genetic diversity, haplotype structure and production differ in two ethnically distinct South African populations
    Authors: M Paximadis, ACP Picton, D Sengupta, M Ramsay, A Puren, CT Tiemessen
    Cytokine, 2021;0(0):155489.
    Species: Human
    Sample Types: Cell Culture Supernates
  45. Skin Sensitization Evaluation of Carbon-Based Graphene Nanoplatelets
    Authors: SH Kim, SH Hong, JH Lee, DH Lee, K Jung, JY Yang, HS Shin, J Lee, J Jeong, JH Oh
    Toxics, 2021;9(3):.
    Species: Human
    Sample Types: cell culture supernatant
  46. Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice
    Authors: L Wang, D Aschenbren, Z Zeng, X Cao, D Mayr, M Mehta, M Capitani, N Warner, J Pan, L Wang, Q Li, T Zuo, S Cohen-Keda, J Lu, RC Ardy, DJ Mulder, D Dissanayak, K Peng, Z Huang, X Li, Y Wang, X Wang, S Li, S Bullers, AN Gammage, K Warnatz, AI Schiefer, G Krivan, V Goda, WHA Kahr, M Lemaire, Genomics E, CY Lu, I Siddiqui, MG Surette, D Kotlarz, KR Engelhardt, HR Griffin, R Rottapel, H Decaluwe, RM Laxer, M Proietti, S Hambleton, S Elcombe, CH Guo, B Grimbacher, I Dotan, SC Ng, SA Freeman, SB Snapper, C Klein, K Boztug, Y Huang, D Li, HH Uhlig, AM Muise
    Nature Genetics, 2021;53(4):500-510.
    Species: Human
    Sample Types: Cell Culture Supernates
  47. Activation of NF-&kapppaB signaling via cytosolic mitochondrial RNA sensing in kerotocytes with mitochondrial DNA common deletion
    Authors: X Zhou, LJ Backman, P Danielson
    Scientific Reports, 2021;11(1):7360.
    Species: Human
    Sample Types: Cell Culture Supernates
  48. Cannabis compounds exhibit anti-inflammatory activity in vitro in COVID-19-related inflammation in lung epithelial cells and pro-inflammatory activity in macrophages
    Authors: SM Anil, N Shalev, AC Vinayaka, S Nadarajan, D Namdar, E Belausov, I Shoval, KA Mani, G Mechrez, H Koltai
    Scientific Reports, 2021;11(1):1462.
    Species: Human
    Sample Types: Cell Culture Supernates
  49. Pulmonary function changes in older adults with and without metabolic syndrome
    Authors: MAR Brandao-Ra, R Moraes-Fer, MC Oliveira-J, A Santos-Dia, ALL Bachi, G Gabriela-P, S de Oliveir, AC Araújo-Ros, LVF Oliveira, CR Frison, WL do Prado, RP Raju, PB Balagopal, RP Vieira
    Scientific Reports, 2021;11(1):17337.
    Species: Human
    Sample Types: Exhaled Breath Condensate (EBC)
  50. Systematic investigation of cytokine signaling activity at the tissue and single-cell levels
    Authors: P Jiang, Y Zhang, B Ru, Y Yang, T Vu, R Paul, A Mirza, G Altan-Bonn, L Liu, E Ruppin, L Wakefield, KW Wucherpfen
    Nature methods, 2021;18(10):1181-1191.
    Species: Human
    Sample Types: Cell Culture Supernates
  51. Adipocytokines in Untreated Newly Diagnosed Rheumatoid Arthritis: Association with Circulating Chemokines and Markers of Inflammation
    Authors: GK Vasileiadi, AC Lundell, Y Zhang, K Andersson, I Gjertsson, A Rudin, C Maglio
    Biomolecules, 2021;11(2):.
    Species: Human
    Sample Types: Plasma
  52. Nobiletin Decreases Inflammatory Mediator Expression in Tumor Necrosis Factor-Stimulated Human Periodontal Ligament Cells
    Authors: Y Hosokawa, I Hosokawa, K Ozaki
    Mediators of Inflammation, 2021;2021(0):5535844.
    Species: Human
    Sample Types: Cell Culture Supernates
  53. Mechanical biofilm disruption causes microbial and immunological shifts in periodontitis patients
    Authors: W Johnston, BT Rosier, A Artacho, M Paterson, K Piela, C Delaney, JL Brown, G Ramage, A Mira, S Culshaw
    Scientific Reports, 2021;11(1):9796.
    Species: Human
    Sample Types: Saliva
  54. Cell Type Dependent Suppression of Inflammatory Mediators by Myocardin Related Transcription Factors
    Authors: L Liu, E Bankell, C Rippe, B Morén, KG Stenkula, BO Nilsson, K Swärd
    Frontiers in Physiology, 2021;12(0):732564.
    Species: Human
    Sample Types: Cell Lysates
  55. LYSMD3: A mammalian pattern recognition receptor for chitin
    Authors: X He, BA Howard, Y Liu, AK Neumann, L Li, N Menon, T Roach, SD Kale, DC Samuels, H Li, T Kite, H Kita, TY Hu, M Luo, CN Jones, UJ Okaa, DL Squillace, BS Klein, CB Lawrence
    Cell Reports, 2021;36(3):109392.
    Species: Human
    Sample Types: Cell Culture Supernates
  56. Sequence edition of single domains modulates the final immune and antimicrobial potential of a new generation of multidomain recombinant proteins
    Authors: R Roca-Pinil, R Holani, A López-Cano, C Saubi, R Baltà-Foix, ER Cobo, E Garcia-Fru, A Arís
    Scientific Reports, 2021;11(1):23798.
    Species: Human
    Sample Types: Cell Culture Supernates
  57. Cigarette Smoke Promotes Interleukin-8 Production in Alveolar Macrophages Through the Reactive Oxygen Species/Stromal Interaction Molecule 1/Ca2+ Axis
    Authors: X Zhu, Y Zhan, Y Gu, Q Huang, T Wang, Z Deng, J Xie
    Frontiers in Physiology, 2021;12(0):733650.
    Species: Human
    Sample Types: Cell Culture Supernates
  58. Inflammatory responses to metal oxide ceramic nanopowders
    Authors: S Jamieson, A Mawdesley, D Deehan, J Kirby, J Holland, A Tyson-Capp
    Scientific Reports, 2021;11(1):10531.
    Species: Human
    Sample Types: Cell Culture Supernates
  59. Food Contaminants Effects on an In Vitro Model of Human Intestinal Epithelium
    Authors: M Guibourden, J Haug, N Chevalier, M Spatz, N Barbezier, J Gay-Quéhei, PM Anton
    Toxics, 2021;9(6):.
    Species: Human
    Sample Types: Cell Culture Supernates
  60. Infection with a hypervirulent strain of Helicobacter pylori primes gastric cells toward intestinal transdifferentiation
    Authors: S Saberi, M Esmaeili, M Tashakorip, M Eshagh Hos, H Baharvand, M Mohammadi
    Microbial pathogenesis, 2021;162(0):105353.
    Species: Human
    Sample Types: Cell Culture Supernates
  61. miR-146a modulates TLR1/2 and 4 induced inflammation and links it with proliferation and lipid production via the indirect regulation of GNG7 in human SZ95 sebocytes
    Authors: K Dull, F Fazekas, D Deák, D Kovács, S Póliska, A Szegedi, CC Zouboulis, D Tör?csik
    Scientific Reports, 2021;11(1):21510.
    Species: Human
    Sample Types: Cell Culture Supernates
  62. Differential Effect of SARS-CoV-2 Spike Glycoprotein 1 on Human Bronchial and Alveolar Lung Mucosa Models: Implications for Pathogenicity
    Authors: M Rahman, M Irmler, S Keshavan, M Introna, J Beckers, L Palmberg, G Johanson, K Ganguly, S Upadhyay
    Viruses, 2021;13(12):.
    Species: Human
    Sample Types: Cell Culture Supernates
  63. Reduced Interleukin-17-Expressing Cells in Cutaneous Melanoma
    Authors: A Tosi, L Nardinocch, ML Carbone, L Capriotti, E Pagani, S Mastroeni, C Fortes, F Scopelliti, C Cattani, F Passarelli, A Rosato, S D'Atri, CM Failla, A Cavani
    Biomedicines, 2021;9(12):.
    Species: Human
    Sample Types: Cell Culture Supernates
  64. Higher CD4/CD8 ratio of pleural effusion predicts better survival for lung cancer patients receiving immune checkpoint inhibitors
    Authors: PH Lee, TY Yang, KC Chen, YH Huang, JS Tseng, KH Hsu, YC Wu, KJ Liu, GC Chang
    Scientific Reports, 2021;11(1):9381.
    Species: Human
    Sample Types: Pleural Effusion
  65. Caspase-8 mutations associated with head and neck cancer differentially retain functional properties related to TRAIL-induced apoptosis and cytokine induction
    Authors: Z Cui, H Dabas, BC Leonard, JV Shiah, JR Grandis, DE Johnson
    Cell Death & Disease, 2021;12(8):775.
    Species: Human
    Sample Types: Cell Culture Supernates
  66. Patient Derived Colonoids as Drug Testing Platforms-Critical Importance of Oxygen Concentration
    Authors: HK Skovdahl, S Gopalakris, TD Svendsen, AVB Granlund, I Bakke, ZG Ginbot, S Thorsvik, A Flatberg, B Sporsheim, J Ostrop, TE Mollnes, AK Sandvik, T Bruland
    Frontiers in Pharmacology, 2021;12(0):679741.
    Species: Human
    Sample Types: Cell Culture Supernates
  67. A highly efficient method for the production and purification of recombinant human CXCL8
    Authors: S McKenna, SP Giblin, RA Bunn, Y Xu, SJ Matthews, JE Pease
    PLoS ONE, 2021;16(10):e0258270.
    Species: Human
    Sample Types: Recombinant Protein
  68. HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway
    Authors: L Feng, L Liang, S Zhang, J Yang, Y Yue, X Zhang
    Autophagy, 2021;0(0):1-20.
    Species: Rat
    Sample Types: Serum
  69. Inflammatory activation of surface molecule shedding by upregulation of the pseudoprotease iRhom2 in colon epithelial cells
    Authors: AA Giese, A Babendreye, P Krappen, A Gross, P Strnad, S Düsterhöft, A Ludwig
    Scientific Reports, 2021;11(1):24230.
    Species: Human
    Sample Types: Cell Culture Supernates
  70. SIRT7 deficiency suppresses inflammation, induces EndoMT, and increases vascular permeability in primary pulmonary endothelial cells
    Authors: AE Wyman, TTT Nguyen, P Karki, ME Tulapurkar, CO Zhang, J Kim, TG Feng, AJ Dabo, NW Todd, IG Luzina, P Geraghty, RF Foronjy, JD Hasday, AA Birukova, SP Atamas, KG Birukov
    Sci Rep, 2020;10(1):12497.
    Species: Human
    Sample Types: Cell Culture Supernates
  71. Anti-CD3 Antibody Treatment Reduces Scar Formation in a Rat Model of Myocardial Infarction
    Authors: B Wernly, V Paar, A Aigner, PM Pilz, BK Podesser, M Förster, C Jung, JP Hofbauer, B Tockner, M Wimmer, T Kraus, LJ Motloch, M Hackl, UC Hoppe, A Kiss, M Lichtenaue
    Cells, 2020;9(2):.
    Species: Human
    Sample Types: Cell Culture Supernates
  72. The Delivery of &alpha1-Antitrypsin Therapy Through Transepidermal Route: Worthwhile to Explore
    Authors: S Tumpara, B Martinez-D, G Gomez-Mari, B Liu, DS DeLuca, E Korenbaum, D Jonigk, F Jugert, FM Wurm, MJ Wurm, T Welte, S Janciauski
    Front Pharmacol, 2020;11(0):983.
    Species: Human
    Sample Types: Cell Culture Supernates
  73. Diet influences the functions of the human intestinal microbiome
    Authors: M De Angelis, I Ferrocino, FM Calabrese, F De Filippi, N Cavallo, S Siragusa, S Rampelli, R Di Cagno, K Rantsiou, L Vannini, N Pellegrini, C Lazzi, S Turroni, N Lorusso, M Ventura, M Chieppa, E Neviani, P Brigidi, PW O'Toole, D Ercolini, M Gobbetti, L Cocolin
    Sci Rep, 2020;10(1):4247.
    Species: Human
    Sample Types: Cell Culture Supernates
  74. Translational research into the effects of cigarette smoke on inflammatory mediators and epithelial TRPV1 in Crohn's disease
    Authors: L Allais, S Verschuere, T Maes, R De Smet, S Devriese, GB Gonzales, H Peeters, K Van Crombr, C Bachert, M De Vos, GG Brusselle, KR Bracke, CA Cuvelier, D Laukens
    PLoS ONE, 2020;15(8):e0236657.
    Species: Human
    Sample Types: Cell Culture Supernates
  75. Neutrophils produce proinflammatory or anti-inflammatory extracellular vesicles depending on the environmental conditions
    Authors: F Kolonics, E Kajdácsi, VJ Farkas, DS Veres, D Khamari, Á Kittel, ML Merchant, KR McLeish, ÁM L?rincz, E Ligeti
    J. Leukoc. Biol., 2020;0(0):.
    Species: Human
    Sample Types: Cell Supernates
  76. Altered iron metabolism in cystic fibrosis macrophages: the impact of CFTR modulators and implications for Pseudomonas aeruginosa survival
    Authors: HF Hazlett, TH Hampton, DS Aridgides, DA Armstrong, JA Dessaint, DL Mellinger, AB Nymon, A Ashare
    Sci Rep, 2020;10(1):10935.
    Species: Human
    Sample Types: Whole Cells
  77. Phenolic and Non-Polar Fractions of the Extracts from Fruits, Leaves, and Twigs of Elaeagnusrhamnoides (L.) A. Nelson-The Implications for Human Barrier Cells
    Authors: B Sadowska, J Rywaniak, A Cichocka, K Cichocka, J ?uchowski, U Wójcik-Boj, M Wi?ckowska, B Ró?alska
    Molecules, 2020;25(9):.
    Species: Human
    Sample Types: Cell Culture Supernates
  78. SARS-CoV-2-specific IgA and limited inflammatory cytokines are present in the stool of select patients with acute COVID-19
    Authors: GJ Britton, A Chen-Liaw, F Cossarini, AE Livanos, MP Spindler, T Plitt, J Eggers, I Mogno, A Gonzalez-R, S Siu, M Tankelevic, L Grinspan, RE Dixon, D Jha, G Martinez-D, F Amanat, DA Hoagland, B tenOever, MC Dubinsky, M Merad, H van Bakel, F Krammer, G Bongers, S Mehandru, JJ Faith
    medRxiv : the preprint server for health sciences, 2020;0(0):.
    Species: Human
    Sample Types: Fecal Supernates
  79. ROCK inhibition modulates the senescence-associated secretory phenotype (SASP) in oral keratinocytes
    Authors: S Niklander, D Bandaru, DW Lambert, KD Hunter
    FEBS Open Bio, 2020;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  80. Epigenetic regulation of miR-29a/miR-30c/DNMT3A axis controls SOD2 and mitochondrial oxidative stress in human mesenchymal stem cells
    Authors: YD Jung, SK Park, D Kang, S Hwang, MH Kang, SW Hong, JH Moon, JS Shin, DH Jin, D You, JY Lee, YY Park, JJ Hwang, CS Kim, N Suh
    Redox Biol, 2020;37(0):101716.
    Species: Human
    Sample Types: Cell Culture Supernates
  81. Toll-like receptor 4-mediated inflammation triggered by extracellular IFI16 is enhanced by lipopolysaccharide binding
    Authors: A Iannucci, V Caneparo, S Raviola, I Debernardi, D Colangelo, R Miggiano, G Griffante, S Landolfo, M Gariglio, M De Andrea
    PLoS Pathog., 2020;16(9):e1008811.
    Species: Human
    Sample Types: Cell Culture Supernates
  82. Clinical Relevance of the Anti-inflammatory Effects of Roflumilast on Human Bronchus: Potentiation by a Long-Acting Beta-2-Agonist
    Authors: H Salvator, A Buenestado, M Brollo, E Naline, T Victoni, E Longchamp, H Tenor, S Grassin-De, P Devillier
    Frontiers in Pharmacology, 2020;11(0):598702.
    Species: Human
    Sample Types: Cell Culture Supernates
  83. Salivary IL-8 and IL-1RA changes induced by exercise in cold-dry and normal conditions
    Authors: I Patlan, MP Jeffrey, D Lewis, J Green-John, S Dogra
    Cytokine, 2020;137(0):155347.
    Species: Human
    Sample Types: Saliva
  84. Regional hyperthermia enhances mesenchymal stem cell recruitment to tumor stroma: Implications for mesenchymal stem cell-based tumor therapy
    Authors: M Tutter, C Schug, KA Schmohl, S Urnauer, C Kitzberger, N Schwenk, M Petrini, C Zach, S Ziegler, P Bartenstei, WA Weber, G Multhoff, E Wagner, LH Lindner, PJ Nelson, C Spitzweg
    Mol Ther, 2020;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  85. Genetic variation in Toll-like receptor-5 and colonization with flagellated bacterial vaginosis-associated bacteria
    Authors: EJ Dela Cruz, TL Fiedler, C Liu, MM Munch, CM Kohler, AR Oot, JM Wallis, J Wang, A Frishman, K Garcia, A Wiser, JE Balkus, S Srinivasan, JL Golob, LK Sycuro, JM Marrazzo, TR Hawn, DN Fredricks
    Infect Immun, 2020;0(0):.
    Species: Human
    Sample Types: Vaginal Swab
  86. An observational study of innate immune responses in patients with acute appendicitis
    Authors: T Peeters, S Martens, V D'Onofrio, MHT Stappers, JCH van der Hi, B Houben, R Achten, LAB Joosten, IC Gyssens
    Sci Rep, 2020;10(1):17352.
    Species: Human
    Sample Types: Cell Culture Supernates
  87. Perfluorooctanoic acid in indoor particulate matter triggers oxidative stress and inflammation in corneal and retinal cells
    Authors: PT Tien, HJ Lin, YY Tsai, YP Lim, CS Chen, CY Chang, CJ Lin, JJ Chen, SM Wu, YJ Huang, L Wan
    Scientific Reports, 2020;10(1):15702.
    Species: Human
    Sample Types: Whole Cells
  88. Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi�strains unveil a role for fibroblasts in neutrophil recruitment and activation
    Authors: AER Oliveira, MCA Pereira, AT Belew, LRP Ferreira, LMN Pereira, EGA Neves, MDCP Nunes, BA Burleigh, WO Dutra, NM El-Sayed, RT Gazzinelli, SMR Teixeira
    PLoS Pathog., 2020;16(8):e1008781.
    Species: Human
    Sample Types: Cell Culture Supernates
  89. N-GSDMD trafficking to neutrophil organelles facilitates IL-1&beta release independently of plasma membrane pores and pyroptosis
    Authors: M Karmakar, M Minns, EN Greenberg, J Diaz-Apont, K Pestonjama, JL Johnson, JK Rathkey, DW Abbott, K Wang, F Shao, SD Catz, GR Dubyak, E Pearlman
    Nat Commun, 2020;11(1):2212.
    Species: Human
    Sample Types: Cell Culture Supernates
  90. Extracellular Vesicles Produced by the Probiotic Propionibacterium freudenreichii CIRM-BIA 129 Mitigate Inflammation by Modulating the NF-&kappaB Pathway
    Authors: VR Rodovalho, BSR da Luz, H Rabah, FLR do Carmo, EL Folador, A Nicolas, J Jardin, V Briard-Bio, H Blottière, N Lapaque, G Jan, Y Le Loir, VA de Carvalh, E Guédon
    Front Microbiol, 2020;11(0):1544.
    Species: Human
    Sample Types: Cell Culture Supernates
  91. CXCL9, CXCL10, and CXCL11; biomarkers of pulmonary inflammation associated with autoimmunity in patients with collagen vascular diseases-associated interstitial lung disease and interstitial pneumonia with autoimmune features
    Authors: M Kameda, M Otsuka, H Chiba, K Kuronuma, T Hasegawa, H Takahashi, H Takahashi
    PLoS ONE, 2020;15(11):e0241719.
    Species: Human
    Sample Types: Serum
  92. Iron Oxide Particles Alter Bacterial Uptake and the LPS-Induced Inflammatory Response in Macrophages
    Authors: LJ Williams, SG Tristram, GR Zosky
    International Journal of Environmental Research and Public Health, 2020;18(1):.
    Species: Human
    Sample Types: Cell Culture Supernates
  93. Proanthocyanidin-Rich Grape Seed Extract Reduces Inflammation and Oxidative Stress and Restores Tight Junction Barrier Function in Caco-2 Colon Cells
    Authors: R Nallathamb, A Poulev, JB Zuk, I Raskin
    Nutrients, 2020;12(6):.
    Species: Human
    Sample Types: Cell Culture Supernates
  94. TLR3 expression by maternal and fetal cells at the maternal-fetal interface in normal and preeclamptic pregnancies
    Authors: LM Gierman, GB Silva, Z Pervaiz, JJ Rakner, SB Mundal, AJ Thaning, I Nervik, M Elschot, S Mathew, LCV Thomsen, L Bjørge, AC Iversen
    J. Leukoc. Biol., 2020;0(0):.
    Species: Human
    Sample Types: Placental Supernates
  95. Data describing expression of formyl peptide receptor 2 in human articular chondrocytes
    Authors: A Strid Holm, CA Jonsson, M Mohaddes, C Lundqvist, H Forsman, I Gjertsson, K Önnheim
    Data Brief, 2020;31(0):105866.
    Species: Human
    Sample Types: Cell Culture Supernates
  96. The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus
    Authors: T Furukawa, N van Rhijn, M Fraczek, F Gsaller, E Davies, P Carr, S Gago, R Fortune-Gr, S Rahman, JM Gilsenan, E Houlder, CH Kowalski, S Raj, S Paul, P Cook, JE Parker, S Kelly, RA Cramer, JP Latgé, S Moye-Rowle, E Bignell, P Bowyer, MJ Bromley
    Nat Commun, 2020;11(1):427.
    Species: Human
    Sample Types: Cell Culture Supernates
  97. Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium
    Authors: I Gomez, B Ward, C Souilhol, C Recarti, M Ariaans, J Johnston, A Burnett, M Mahmoud, LA Luong, L West, M Long, S Parry, R Woods, C Hulston, B Benedikter, C Niespolo, R Bazaz, S Francis, E Kiss-Toth, M van Zandvo, A Schober, P Hellewell, PC Evans, V Ridger
    Nat Commun, 2020;11(1):214.
    Species: Human
    Sample Types: Cell Culture Supernates
  98. Resveratrol treatment reduces expression of MCP-1, IL-6, IL-8 and RANTES in endometriotic stromal cells
    Authors: R Kolahdouz-, F Shidfar, S Khodaverdi, T Arablou, S Heidari, N Rashidi, AA Delbandi
    Journal of Cellular and Molecular Medicine, 2020;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  99. N-Acetyl Cysteine Modulates the Inflammatory and Oxidative Stress Responses of Rescued Growth-Arrested Dental Pulp Microtissues Exposed to TEGDMA in ECM
    Authors: G Kaufman, D Skrtic
    Int J Mol Sci, 2020;21(19):.
    Species: Human
    Sample Types: Cell Culture Supernates
  100. Interleukin (IL)-17/IL-36 axis participates to the crosstalk between endothelial cells and keratinocytes during inflammatory skin responses
    Authors: L Mercurio, CM Failla, L Capriotti, C Scarponi, F Facchiano, M Morelli, S Rossi, G Pagnanelli, C Albanesi, A Cavani, S Madonna
    PLoS ONE, 2020;15(4):e0222969.
    Species: Human
    Sample Types: Cell Culture Supernates
  101. Root Extracts From Ononis spinosa Inhibit IL-8 Release via Interactions With Toll-Like Receptor 4 and Lipopolysaccharide
    Authors: V Spiegler, B Gierlikows, T Saenger, JN Addotey, J Sendker, J Jose, AK Kiss, A Hensel
    Front Pharmacol, 2020;11(0):889.
    Species: Human
    Sample Types: Cell Culture Supernates
  102. OPTN recruitment to a Golgi-proximal compartment regulates immune signalling and cytokine secretion
    Authors: T O'Loughlin, AJ Kruppa, ALR Ribeiro, JR Edgar, A Ghannam, AM Smith, F Buss
    J. Cell. Sci., 2020;0(0):.
    Species: Human
    Sample Types: Tissue Culture Supernates
  103. A protein microarray analysis of amniotic fluid proteins for the prediction of spontaneous preterm delivery in women with preterm premature rupture of membranes at 23 to 30 weeks of gestation
    Authors: HJ Kim, KH Park, YM Kim, E Joo, K Ahn, S Shin
    PLoS ONE, 2020;15(12):e0244720.
    Species: Human
    Sample Types: Amniotic Fluid
  104. Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease
    Authors: FJ Ryan, AM Ahern, RS Fitzgerald, EJ Laserna-Me, EM Power, AG Clooney, KW O'Donoghue, PJ McMurdie, S Iwai, A Crits-Chri, D Sheehan, C Moran, B Flemer, AL Zomer, A Fanning, J O'Callagha, J Walton, A Temko, W Stack, L Jackson, SA Joyce, S Melgar, TZ DeSantis, JT Bell, F Shanahan, MJ Claesson
    Nat Commun, 2020;11(1):1512.
    Species: Human
    Sample Types: Cell Culture Supernates
  105. IL-37 is increased in brains of children with autism spectrum disorder and inhibits human microglia stimulated by neurotensin
    Authors: I Tsilioni, AB Patel, H Pantazopou, S Berretta, P Conti, SE Leeman, TC Theoharide
    Proc. Natl. Acad. Sci. U.S.A., 2019;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  106. Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression
    Authors: Q Xu, Q Long, D Zhu, D Fu, B Zhang, L Han, M Qian, J Guo, J Xu, L Cao, YE Chin, JP Coppé, EW Lam, J Campisi, Y Sun
    Aging Cell, 2019;0(0):e13027.
    Species: Human
    Sample Types: Serum
  107. Disrupting prolonged sitting reduces IL-8 and lower leg swell in active young adults
    Authors: S Dogra, M Wolf, MP Jeffrey, RCA Foley, H Logan-Spre, H Jones-Tagg, JM Green-John
    BMC Sports Sci Med Rehabil, 2019;11(0):23.
    Species: Human
    Sample Types: Saliva
  108. Mitochondrial dysfunction increases pro-inflammatory cytokine production and impairs repair and corticosteroid responsiveness in lung epithelium
    Authors: RF Hoffmann, MR Jonker, SM Brandenbur, HG de Bruin, NHT Ten Hacken, AJM van Ooster, IH Heijink
    Sci Rep, 2019;9(1):15047.
    Species: Human
    Sample Types: Cell Culture Supernates
  109. ADP secreted by dying melanoma cells mediates chemotaxis and chemokine secretion of macrophages via the purinergic receptor P2Y12
    Authors: L Kloss, C Dollt, K Schledzews, A Krewer, S Melchers, C Manta, C Sticht, C Torre, J Utikal, V Umansky, A Schmieder
    Cell Death Dis, 2019;10(10):760.
    Species: Human
    Sample Types: Cell Culture Supernates
  110. Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface
    Authors: CM Weight, C Venturini, S Pojar, SP Jochems, J Reiné, E Nikolaou, C Solórzano, M Noursadegh, JS Brown, DM Ferreira, RS Heyderman
    Nat Commun, 2019;10(1):3060.
    Species: Human
    Sample Types: Cell Culture Supernates
  111. Interleukin 1 Receptor-Like 1 (IL1RL1) Promotes Airway Bacterial and Viral Infection and Inflammation
    Authors: N Schaunaman, A Sanchez, KG Dimasuay, N Pavelka, M Numata, R Alam, RJ Martin, HW Chu
    Infect. Immun., 2019;87(7):.
    Species: Human
    Sample Types: Cell Culture Supernates
  112. LABAs and p38MAPK Inhibitors Reverse the Corticosteroid-Insensitivity of IL-8 in Airway Smooth Muscle Cells of COPD
    Authors: J Knobloch, D Jungck, J Kronsbein, E Stoelben, K Ito, A Koch
    J Clin Med, 2019;8(12):.
    Species: Human
    Sample Types: Cell Culture Supernates
  113. C13 Megastigmane Derivatives From Epipremnum pinnatum: beta-Damascenone Inhibits the Expression of Pro-Inflammatory Cytokines and Leukocyte Adhesion Molecules as Well as NF-kappaB Signaling
    Authors: SP Pan, T Pirker, O Kunert, N Kretschmer, S Hummelbrun, SL Latkolik, J Rappai, VM Dirsch, V Bochkov, R Bauer
    Front Pharmacol, 2019;10(0):1351.
    Species: Human
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  114. FOXO3a regulates rhinovirus-induced innate immune responses in airway epithelial cells
    Authors: J Gimenes-Ju, N Owuar, HR Vari, W Li, N Xander, S Kotnala, US Sajjan
    Sci Rep, 2019;9(1):18180.
    Species: Human
    Sample Types: Cell Culture Supernates
  115. Replication of Genome-Wide Association Analysis Identifies New Susceptibility Loci at Long Noncoding RNA Regions for Vogt-Koyanagi-Harada Disease
    Authors: J Qi, L Du, J Deng, Y Qin, G Su, S Hou, M Lv, Q Zhang, A Kijlstra, P Yang
    Invest. Ophthalmol. Vis. Sci., 2019;60(14):4820-4829.
    Species: Human
    Sample Types: Cell Culture Supernates
  116. Ouabain signaling in oral squamous cell carcinoma cells
    Authors: S Saito, M Ohtsu, M Asano, T Ishigami
    J Oral Sci, 2019;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  117. Bleomycin hydrolase regulates the release of chemokines important for inflammation and wound healing by keratinocytes
    Authors: R Riise, L Odqvist, J Mattsson, S Monkley, SM Abdillahi, C Tyrchan, D Muthas, LF Yrlid
    Sci Rep, 2019;9(1):20407.
    Species: Human
    Sample Types: Cell Culture Supernates
  118. Identification of α-N-catenin as a novel tumor suppressor in neuroblastoma
    Authors: J Qiao, EJ Rellinger, KW Kim, CM Powers, S Lee, H Correa, DH Chung
    Oncotarget, 2019;10(49):5028-5040.
    Species: Human
    Sample Types: Cell Culture Supernates
  119. ?-Difluoromethylornithine reduces gastric carcinogenesis by causing mutations in Helicobacter pylori cagY
    Authors: JC Sierra, G Suarez, MB Piazuelo, PB Luis, DR Baker, J Romero-Gal, DP Barry, C Schneider, DR Morgan, RM Peek, AP Gobert, KT Wilson
    Proc. Natl. Acad. Sci. U.S.A., 2019;0(0):.
    Species: Human
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  120. R. nukuhivensis acts by reinforcing skin barrier function, boosting skin immunity and by inhibiting IL-22 induced keratinocyte hyperproliferation
    Authors: F Abdallah, G Lecellier, P Raharivelo, C Pichon
    Sci Rep, 2019;9(1):4132.
    Species: Human
    Sample Types: Cell Culture Supernates
  121. Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke
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    Exp. Gerontol., 2019;118(0):78-87.
    Species: Human
    Sample Types: Cell Culture Supernates
  122. Calcineurin inhibitor Tacrolimus impairs host immune response against urinary tract infection
    Authors: D Emal, E Rampanelli, N Claessen, FJ Bemelman, JC Leemans, S Florquin, MC Dessing
    Sci Rep, 2019;9(1):106.
    Species: Human
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  123. Toll-like receptor 3 regulates Zika virus infection and associated host inflammatory response in primary human astrocytes
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    PLoS ONE, 2019;14(2):e0208543.
    Species: Human
    Sample Types: Cell Culture Supernates
  124. Flagellin-independent effects of a Toll-like receptor 5 polymorphism in the inflammatory response to Burkholderia pseudomallei
    Authors: AK Dickey, N Chantratit, S Tandhavana, D Ducken, L Lovelace-M, S Seal, J Robertson, ND Myers, S Schwarz, MM Wurfel, S Kosamo, TE West
    PLoS Negl Trop Dis, 2019;13(5):e0007354.
    Species: Human
    Sample Types: Cell Culture Supernates
  125. An in vitro investigation of the inflammatory response to the strain amplitudes which occur during high frequency oscillation ventilation and conventional mechanical ventilation
    Authors: C Harris, SD Thorpe, S Rushwan, W Wang, CL Thompson, JL Peacock, MM Knight, B Gooptu, A Greenough
    J Biomech, 2019;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  126. The contraceptive medroxyprogesterone acetate, unlike norethisterone, directly increases R5 HIV-1 infection in human cervical explant tissue at physiologically relevant concentrations
    Authors: RM Ray, MF Maritz, C Avenant, M Tomasicchi, S Dlamini, Z van der Sp, JP Hapgood
    Sci Rep, 2019;9(1):4334.
    Species: Human
    Sample Types: Tissue Culture Supernates
  127. Evaluating S. flexneri pathogenesis in the human enteroid model
    Authors: S Ranganatha, M Doucet, CL Grassel, B Delaine-El, NC Zachos, EM Barry
    Infect. Immun., 2019;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  128. The human glomerular endothelial cells are potent pro-inflammatory contributors in an in vitro model of lupus nephritis
    Authors: P Dimou, RD Wright, KL Budge, A Midgley, SC Satchell, M Peak, MW Beresford
    Sci Rep, 2019;9(1):8348.
    Species: Human
    Sample Types: Cell Culture Supernates
  129. Resistance to lysosomotropic drugs used to treat kidney and breast cancers involves autophagy and inflammation and converges in inducing CXCL5
    Authors: S Giuliano, M Dufies, PD Ndiaye, J Viotti, D Borchielli, J Parola, V Vial, Y Cormerais, M Ohanna, V Imbert, E Chamorey, N Rioux-Lecl, A Savina, JM Ferrero, B Mograbi, G Pagès
    Theranostics, 2019;9(4):1181-1199.
    Species: Human
    Sample Types: Cell Culture Supernates
  130. Exploiting interconnected synthetic lethal interactions between PARP inhibition and cancer cell reversible senescence
    Authors: H Fleury, N Malaquin, V Tu, S Gilbert, A Martinez, MA Olivier, A Sauriol, L Communal, K Leclerc-De, E Carmona, D Provencher, AM Mes-Masson, F Rodier
    Nat Commun, 2019;10(1):2556.
    Species: Human
    Sample Types: Cell Culture Supernates
  131. Ibrutinib induces multiple functional defects in the neutrophil response against Aspergillus fumigatus
    Authors: D Blez, M Blaize, C Soussain, A Boissonnas, A Meghraoui-, N Menezes, A Portalier, C Combadière, V Leblond, D Ghez, A Fekkar
    Haematologica, 2019;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  132. A Unique Pattern of Mesothelial-Mesenchymal Transition Induced in the Normal Peritoneal Mesothelium by High-Grade Serous Ovarian Cancer
    Authors: M Paku?a, P Uruski, A Niklas, A Wo?niak, D Szpurek, A Tykarski, J Miku?a-Pie, K Ksi??ek
    Cancers (Basel), 2019;11(5):.
    Species: Human
    Sample Types: Cell Culture Supernates
  133. Activation of a TLR9 mediated innate immune response in preeclampsia
    Authors: RD Williamson, FP McCarthy, LC Kenny, CM McCarthy
    Sci Rep, 2019;9(1):5920.
    Species: Human
    Sample Types: Plasma
  134. 6-Shogaol Suppresses 2-Amino-1-Methyl-6-Phenylimidazo [4,5-b] Pyridine (PhIP)-Induced Human 786-O Renal Cell Carcinoma Osteoclastogenic Activity and Metastatic Potential
    Authors: IJ Yeh, SC Chen, MC Yen, YH Wu, CH Hung, PL Kuo
    Nutrients, 2019;11(10):.
    Species: Human
    Sample Types: Cell Culture Supernates
  135. Intrapulmonary Autoantibodies to HSP72 Are Associated with Improved Outcomes in IPF
    Authors: R Mills, A Mathur, LM Nicol, JJ Walker, AA Przybylski, AC Mackinnon, SEM Howie, WAH Wallace, I Dransfield, N Hirani
    J Immunol Res, 2019;2019(0):1845128.
    Species: Human
    Sample Types: Cell Culture Supernates
  136. Differential bronchial epithelial response regulated by ?Np63: a functional understanding of the epithelial shedding found in asthma
    Authors: T Kubo, M Tsujiwaki, Y Hirohashi, T Tsukahara, T Kanaseki, M Nakatsugaw, T Hasegawa, T Torigoe
    Lab. Invest., 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  137. Human Mesenchymal Stem Cell Secretome from Bone Marrow or Adipose-Derived Tissue Sources for Treatment of Hypoxia-Induced Pulmonary Epithelial Injury
    Authors: N Shologu, M Scully, JG Laffey, D O'Toole
    Int J Mol Sci, 2018;19(10):.
    Species: Human
    Sample Types: Cell Culture Supernates
  138. iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE
    Authors: I Oikonomidi, E Burbridge, M Cavadas, G Sullivan, B Collis, H Naegele, D Clancy, J Brezinova, T Hu, A Bileck, C Gerner, A Bolado, A von Kriegs, SJ Martin, F Steinberg, K Strisovsky, C Adrain
    Elife, 2018;7(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  139. Neutrophil recruitment to inflamed joints can occur without cellular priming
    Authors: L Björkman, K Christenso, L Davidsson, J Mårtensson, F Amirbeagi, A Welin, H Forsman, A Karlsson, C Dahlgren, J Bylund
    J. Leukoc. Biol., 2018;0(0):.
    Species: Human
    Sample Types: Cell Lysates
  140. CD47 as a potential prognostic marker for oral leukoplakia and oral squamous cell carcinoma
    Authors: X Ye, X Wang, R Lu, J Zhang, X Chen, G Zhou
    Oncol Lett, 2018;15(6):9075-9080.
    Species: Human
    Sample Types: Cell Culture Supernates
  141. Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy
    Authors: SE Logue, EP McGrath, P Cleary, S Greene, K Mnich, A Almanza, E Chevet, RM Dwyer, A Oommen, P Legembre, F Godey, EC Madden, B Leuzzi, J Obacz, Q Zeng, JB Patterson, R Jäger, AM Gorman, A Samali
    Nat Commun, 2018;9(1):3267.
    Species: Human
    Sample Types: Cell Culture Supernates
  142. The effects of repeated Toll-like receptors 2 and 4 stimulation in COPD alveolar macrophages
    Authors: SR Lea, SL Reynolds, M Kaur, KD Simpson, SR Hall, EM Hessel, D Singh
    Int J Chron Obstruct Pulmon Dis, 2018;13(0):771-780.
    Species: Human
    Sample Types: Cell Culture Supernates
  143. Serum from patients with chronic obstructive pulmonary disease induces senescence-related phenotype in bronchial epithelial cells
    Authors: B Ku?nar-Kam, J Miku?a-Pie, A Witucka, A Romaniuk, N Konieczna, B Rubi?, K Ksi??ek, A Tykarski, H Batura-Gab
    Sci Rep, 2018;8(1):12940.
    Species: Human
    Sample Types: Cell Culture Supernates
  144. Anti-inflammatory activity of CKC-containing cationic emulsion eye drop vehicles
    Authors: P Daull, S Guenin, V Hamon de A, JS Garrigue
    Mol. Vis., 2018;24(0):459-470.
    Species: Human
    Sample Types: Cell Culture Supernates
  145. IL-6 and CXCL8 mediate osteosarcoma-lung interactions critical to metastasis
    Authors: AC Gross, H Cam, DA Phelps, AJ Saraf, HK Bid, M Cam, CA London, SA Winget, MA Arnold, L Brandolini, X Mo, JM Hinckley, PJ Houghton, RD Roberts
    JCI Insight, 2018;3(16):.
    Species: Human
    Sample Types: Cell Culture Supernates
  146. PGL I expression in live bacteria allows activation of a CD206/PPAR? cross-talk that may contribute to successful Mycobacterium leprae colonization of peripheral nerves
    Authors: CC Díaz Acost, AA Dias, TLSA Rosa, LR Batista-Si, PS Rosa, TG Toledo-Pin, FDMR Costa, FA Lara, LS Rodrigues, KA Mattos, EN Sarno, PT Bozza, C Guilhot, M de Berrêdo, MCV Pessolani
    PLoS Pathog., 2018;14(7):e1007151.
    Species: Human
    Sample Types: Cell Culture Supernates
  147. Respiratory hazard assessment of combined exposure to complete gasoline exhaust and respirable volcanic ash in a multicellular human lung model at the air-liquid interface
    Authors: I Tomašek, CJ Horwell, C Bisig, DE Damby, P Comte, J Czerwinski, A Petri-Fink, MJD Clift, B Drasler, B Rothen-Rut
    Environ. Pollut., 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  148. Interferon-gamma inhibits seminal plasma induction of colony stimulating factor 2 in mouse and human reproductive tract epithelial cells
    Authors: DJ Sharkey, DJ Glynn, JE Schjenken, KP Tremellen, SA Robertson
    Biol. Reprod., 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  149. Reduced MBD2 expression enhances airway inflammation in bronchial epithelium in COPD
    Authors: Z Zeng, M Li, J Chen, Q Li, Q Ning, J Zhao, Y Xu, J Xie, J Yu
    Int J Chron Obstruct Pulmon Dis, 2018;13(0):703-715.
    Species: Human
    Sample Types: Cell Culture Supernates
  150. Targeting SPINK1 in the damaged tumour microenvironment alleviates therapeutic resistance
    Authors: F Chen, Q Long, D Fu, D Zhu, Y Ji, L Han, B Zhang, Q Xu, B Liu, Y Li, S Wu, C Yang, M Qian, J Xu, S Liu, L Cao, YE Chin, EW Lam, JP Coppé, Y Sun
    Nat Commun, 2018;9(1):4315.
    Species: Human
    Sample Types: Serum
  151. Allergic Conjunctivitis-induced Retinal Inflammation Promotes Myopia Progression
    Authors: CC Wei, YJ Kung, CS Chen, CY Chang, CJ Lin, PT Tien, HY Chang, HJ Chen, YS Huang, HJ Lin, L Wan
    EBioMedicine, 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  152. Effects of agricultural organic dusts on human lung-resident mesenchymal stem (stromal) cell function
    Authors: TM Nordgren, KL Bailey, AJ Heires, D Katafiasz, DJ Romberger
    Toxicol. Sci., 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  153. Rhododendron album Blume extract inhibits TNF-?/IFN-?-induced chemokine production via blockade of NF-?B and JAK/STAT activation in human epidermal keratinocytes
    Authors: JW Park, HS Lee, Y Lim, JH Paik, OK Kwon, JH Kim, I Paryanto, P Yunianto, S Choi, SR Oh, KS Ahn
    Int. J. Mol. Med., 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  154. Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection
    Authors: V Ciancarell, L Lembo-Fazi, I Paciello, AK Bruno, S Jaillon, S Berardi, M Barbagallo, S Meron-Suda, D Cohen, A Molinaro, G Rossi, C Garlanda, ML Bernardini
    PLoS Pathog., 2018;14(12):e1007469.
    Species: Human
    Sample Types: Cell Culture Supernates
  155. Copy number variations and founder effect underlying complete IL-10R? deficiency in Portuguese kindreds
    Authors: F Charbit-He, B Bègue, A Sierra, S Hanein, MC Stolzenber, Z Li, S Pellegrini, N Garcelon, M Jeanpierre, B Neven, I Loge, C Picard, J Rosain, J Bustamante, M Le Lorc'h, B Pigneur, A Fernandes,, F Rieux-Lauc, J Amil Dias, FM Ruemmele, N Cerf-Bensu
    PLoS ONE, 2018;13(10):e0205826.
    Species: Human
    Sample Types: Cell Culture Supernates
  156. TiO2 nanoparticles can selectively bind CXCL8 impacting on neutrophil chemotaxis
    Authors: J Batt, M Milward, I Chapple, M Grant, H Roberts, O Addison
    Eur Cell Mater, 2018;35(0):13-24.
  157. Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps
    Authors: L Tengroth, J Arebro, O Larsson, C Bachert, SK Georén, LO Cardell
    Sci Rep, 2018;8(1):1561.
    Species: Human
    Sample Types: Cell Culture Supernates
  158. Variable localization of Toll-like receptors in human fallopian tube epithelial cells
    Authors: F Amjadi, Z Zandieh, E Salehi, R Jafari, N Ghasemi, A Aflatoonia, A Fazeli, R Aflatoonia
    Clin Exp Reprod Med, 2018;45(1):1-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  159. Analysis of the association between Fc receptor family gene polymorphisms and ocular Beh�et's disease in Han Chinese
    Authors: D Zhang, J Qin, L Li, G Su, G Huang, Q Cao, A Kijlstra, P Yang
    Sci Rep, 2018;8(1):4850.
    Species: Human
    Sample Types: Cell Culture Supernates
  160. Genome wide analysis of TLR1/2- and TLR4-activated SZ95 sebocytes reveals a complex immune-competence and identifies serum amyloid A as a marker for activated sebaceous glands
    Authors: D Tör?csik, D Kovács, S Póliska, Z Szentkeres, M Lovászi, K Hegyi, A Szegedi, CC Zouboulis, M Ståhle
    PLoS ONE, 2018;13(6):e0198323.
    Species: Human
    Sample Types: Cell Culture Supernates
  161. Comparison of pro- and anti-inflammatory responses in paired human primary airway epithelial cells and alveolar macrophages
    Authors: RA Mubarak, N Roberts, RJ Mason, S Alper, HW Chu
    Respir. Res., 2018;19(1):126.
    Species: Human
    Sample Types: Cell Culture Supernates
  162. Complement C5a Receptor 1 Exacerbates the Pathophysiology of N.�meningitidis Sepsis and Is a Potential Target for Disease Treatment
    Authors: JB Herrmann, M Muensterma, L Strobel, A Schubert-U, TM Woodruff, SD Gray-Owen, A Klos, KO Johswich
    MBio, 2018;9(1):.
    Species: Human
    Sample Types: Whole Blood
  163. Age-Related Changes to Human Tear Composition
    Authors: A Micera, A Di Zazzo, G Esposito, R Longo, W Foulsham, R Sacco, R Sgrulletta, S Bonini
    Invest. Ophthalmol. Vis. Sci., 2018;59(5):2024-2031.
    Species: Human
    Sample Types: Tears
  164. SIRT1/FoxO3 axis alteration leads to aberrant immune responses in bronchial epithelial cells
    Authors: S Di Vincenz, IH Heijink, JA Noordhoek, C Cipollina, L Siena, A Bruno, M Ferraro, DS Postma, M Gjomarkaj, E Pace
    J. Cell. Mol. Med., 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  165. Association of Long Noncoding RNAs Polymorphisms With Ankylosing Spondylitis, Vogt-Koyanagi-Harada Disease, and Behcet's Disease
    Authors: Y Yue, J Zhang, L Yang, S Liu, J Qi, Q Cao, C Zhou, Y Wang, A Kijlstra, P Yang, S Hou
    Invest. Ophthalmol. Vis. Sci., 2018;59(2):1158-1166.
    Species: Human
    Sample Types: Cell Culture Supernates
  166. Silver nanoparticles promote the emergence of heterogeneic human neutrophil sub-populations
    Authors: JA Fraser, S Kemp, L Young, M Ross, M Prach, GR Hutchison, E Malone
    Sci Rep, 2018;8(1):7506.
    Species: Human
    Sample Types: Cell Culture Supernates
  167. Allostimulatory capacity of conditionally immortalized proximal tubule cell lines for bioartificial kidney application
    Authors: M Mihajlovic, LP van den He, JG Hoenderop, J Jansen, MJ Wilmer, AJF Westheim, WA Allebes, D Stamatiali, LB Hilbrands, R Masereeuw
    Sci Rep, 2017;7(1):7103.
    Species: Human
    Sample Types: Cell Culture Supernates
  168. Little Cigars are More Toxic than Cigarettes and Uniquely Change the Airway Gene and Protein Expression
    Authors: A Ghosh, SH Abdelwahab, SL Reeber, B Reidel, AJ Marklew, AJ Garrison, S Lee, H Dang, AH Herring, GL Glish, M Kesimer, R Tarran
    Sci Rep, 2017;7(0):46239.
    Species: Human
    Sample Types: Cell Culture Supernates
  169. Human gestation-associated tissues express functional cytosolic nucleic acid sensing pattern recognition receptors
    Authors: AH Bryant, GE Menzies, LM Scott, S Spencer-Ha, LB Davies, RA Smith, RH Jones, CA Thornton
    Clin. Exp. Immunol, 2017;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  170. Vitamin D both facilitates and attenuates the cellular response to lipopolysaccharide
    Authors: L Chen, MS Eapen, GR Zosky
    Sci Rep, 2017;7(0):45172.
    Species: Human
    Sample Types: Cell Culture Supernates
  171. Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory FADDosome Complex upon TRAIL Stimulation
    Authors: CM Henry, SJ Martin
    Mol. Cell, 2017;65(4):715-729.e5.
    Species: Human
    Sample Types: Cell Culture Supernates
  172. Changes in peripheral immune cell numbers and functions in octogenarian walkers - an acute exercise study
    Authors: KS van der Ge, Q Wang, TM Eijsvogels, HJ Koenen, I Joosten, E Brouwer, MT Hopman, JF Jacobs, AM Boots
    Immun Ageing, 2017;14(0):5.
    Species: Human
    Sample Types: Cell Culture Supernates
  173. IL-27 Modulates Chemokine Production in TNF-? -Stimulated Human Oral Epithelial Cells
    Authors: Y Hosokawa, I Hosokawa, K Ozaki, T Matsuo
    Cell. Physiol. Biochem., 2017;43(3):1198-1206.
    Species: Human
    Sample Types: Cell Culture Supernates
  174. Acute cigarette smoke exposure activates apoptotic and inflammatory programs but a second stimulus is required to induce epithelial to mesenchymal transition in COPD epithelium
    Authors: LA Murray, R Dunmore, A Camelo, CA Da Silva, MJ Gustavsson, DM Habiel, TL Hackett, CM Hogaboam, MA Sleeman, DA Knight
    Respir. Res., 2017;18(1):82.
    Species: Human
    Sample Types: Cell Culture Supernates
  175. Prevention of influenza virus induced bacterial superinfection by standardized Echinacea purpurea, via regulation of surface receptor expression in human bronchial epithelial cells
    Authors: V Selvarani, S Roland, S Andy, H James
    Virus Res, 2017;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  176. The Role of Shed PrP(c) in the Neuropathogenesis of HIV Infection
    Authors: BW Megra, EA Eugenin, JW Berman
    J. Immunol., 2017;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  177. Amniotic Fluid Infection, Cytokine Levels, and Mortality and Adverse Pulmonary, Intestinal, and Neurologic Outcomes in Infants at 32 Weeks' Gestation or Less
    Authors: EY Jung, KH Park, BR Han, SH Cho, HN Yoo, J Lee
    J. Korean Med. Sci, 2017;32(3):480-487.
    Species: Human
    Sample Types: Amniotic Fluid
  178. The Effect of a p38 Mitogen-Activated Protein Kinase Inhibitor on Cellular Senescence of Cultivated Human Corneal Endothelial Cells
    Authors: A Hongo, N Okumura, M Nakahara, EP Kay, N Koizumi
    Invest. Ophthalmol. Vis. Sci., 2017;58(9):3325-3334.
    Species: Human
    Sample Types: Cell Culture Supernates
  179. Penicillinase-resistant antibiotics induce non-immune-mediated cholestasis through HSP27 activation associated with PKC/P38 and PI3K/AKT signaling pathways
    Authors: A Burban, A Sharanek, R Hüe, M Gay, S Routier, A Guillouzo, C Guguen-Gui
    Sci Rep, 2017;7(1):1815.
    Species: Human
    Sample Types: Cell Culture Supernates
  180. Mild intracellular acidification by dexamethasone attenuates mitochondrial dysfunction in a human inflammatory proximal tubule epithelial cell model
    Authors: TJJ Schirris, J Jansen, M Mihajlovic, LP van den He, R Masereeuw, FGM Russel
    Sci Rep, 2017;7(1):10623.
    Species: Human
    Sample Types: Cell Culture Supernates
  181. Malaria pigment stimulates chemokine production by human microvascular endothelium
    Authors: N Basilico, Y Corbett, S Alessandro, S Parapini, M Prato, D Girelli, P Misiano, P Olliaro, D Taramelli
    Acta Trop., 2017;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  182. Activated Tissue-Resident Mesenchymal Stromal Cells Regulate Natural Killer Cell Immune and Tissue-Regenerative Function
    Authors: RM Petri, A Hackel, K Hahnel, CA Dumitru, K Bruderek, SB Flohe, A Paschen, S Lang, S Brandau
    Stem Cell Reports, 2017;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  183. Collagen-Based Medical Device as a Stem Cell Carrier for Regenerative Medicine
    Authors: L Aubert, M Dubus, H Rammal, C Bour, C Mongaret, C Boulagnon-, R Garnotel, C Schneider, R Rahouadj, C Laurent, SC Gangloff, F Velard, C Mauprivez, H Kerdjoudj
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    Species: Human
    Sample Types: Cell Culture Supernates
  184. Clinical significance of histologic chorioamnionitis with a negative amniotic fluid culture in patients with preterm labor and premature membrane rupture
    Authors: JW Park, KH Park, EY Jung
    PLoS ONE, 2017;12(3):e0173312.
    Species: Human
    Sample Types: Amniotic Fluid
  185. The effects of exogenous lipid on THP-1 cells: an in vitro model of airway aspiration?
    Authors: YA Hayman, LR Sadofsky, JD Williamson, SP Hart, AH Morice
    ERJ Open Res, 2017;3(1):.
    Species: Human
    Sample Types: Cell Culture Supernates
  186. Bcl-3 induced by IL-22 via STAT3 activation acts as a potentiator of psoriasis-related gene expression in epidermal keratinocytes
    Authors: M Tohyama, Y Shirakata, Y Hanakawa, X Dai, K Shiraishi, M Murakami, S Miyawaki, H Mori, R Utsunomiya, K Masuda, K Hashimoto, K Sayama
    Eur. J. Immunol., 2017;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  187. Chlamydial Lipoproteins Stimulate Toll-Like Receptors 1/2 Mediated Inflammatory Responses through MyD88-Dependent Pathway
    Authors: Y Wang, Q Liu, D Chen, J Guan, L Ma, G Zhong, H Shu, X Wu
    Front Microbiol, 2017;8(0):78.
    Species: Human
    Sample Types: Cell Culture Supernates
  188. Experimental type 2 diabetes induction reduces serum vaspin, but not serum omentin, in Wistar rats
    Authors: CA Castro, KA da Silva, MM Buffo, KNZ Pinto, FO Duarte, KO Nonaka, FF Aníbal, ACGO Duarte
    Int J Exp Pathol, 2017;0(0):.
    Species: Human
    Sample Types: Serum
  189. Acute cigarette smoke exposure activates apoptotic and inflammatory programs but a second stimulus is required to induce epithelial to mesenchymal transition in COPD epithelium.
    Authors: Lynne A Murray, Rebecca Dunmore, Ana Camelo, Carla A Da Silva, Malin J Gustavsso, David M Habiel, Tillie L Hackett, Cory M Hogaboam, Matthew A Sleeman, Darryl A Knight
    Respiratory Research, 2017;0(0):1465-993X.
    Species: Human
    Sample Types: Cell Culture Supernates
  190. Alpha1-antitrypsin binds hemin and prevents oxidative activation of human neutrophils: putative pathophysiological significance
    Authors: S Janciauski, S Tumpara, M Wiese, S Wrenger, V Vijayan, F Gueler, R Chen, K Madyaningr, R Mahadeva, T Welte, S Immenschuh, J Chorostows
    J. Leukoc. Biol., 2017;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  191. The Proangiogenic Capabilities of Malignant Ascites Generated by Aggressive Ovarian Tumors
    Authors: J Miku?a-Pie, P Uruski, S Szubert, K Maksin, R Moszy?ski, D Szpurek, A Wo?niak, S Sajdak, A Tykarski, K Ksi??ek
    Biomed Res Int, 2017;2017(0):2592496.
    Species: Human
    Sample Types: Cell Culture Supernates
  192. The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2
    Authors: T Hartwig, A Montinaro, S von Karste, A Sevko, S Surinova, A Chakravart, L Taraborrel, P Draber, E Lafont, F Arce Varga, MA El-Bahrawy, SA Quezada, H Walczak
    Mol. Cell, 2017;65(4):730-742.e5.
    Species: Human
    Sample Types: Cell Culture Supernates
  193. Evaluation of a human in vitro hepatocyte-NPC co-culture model for the prediction of idiosyncratic drug-induced liver injury: A pilot study
    Authors: A Granitzny, J Knebel, M Müller, A Braun, P Steinberg, C Dasenbrock, T Hansen
    Toxicol Rep, 2017;4(0):89-103.
    Species: Human
    Sample Types: Cell Culture Supernates
  194. Increased expression of Siglec-9 in chronic obstructive pulmonary disease
    Authors: Z Zeng, M Li, M Wang, X Wu, Q Li, Q Ning, J Zhao, Y Xu, J Xie
    Sci Rep, 2017;7(1):10116.
    Species: Human
    Sample Types: Cell Culture Supernates
  195. Frequency and clinical significance of short cervix in patients with preterm premature rupture of membranes
    Authors: SM Lee, KH Park, EY Jung, JA Jang, HN Yoo
    PLoS ONE, 2017;12(3):e0174657.
    Species: Human
    Sample Types: Amniotic Fluid
  196. Amyloid precursor protein mediated changes in intestinal epithelial phenotype in vitro.
    Authors: Puig K, Manocha G, Combs C
    PLoS ONE, 2016;10(3):e0119534.
    Species: Human
    Sample Types: Cell Culture Supernates
  197. Integrated microRNA and mRNA Signature Associated with the Transition from the Locally Confined to the Metastasized Clear Cell Renal Cell Carcinoma Exemplified by miR-146-5p.
    Authors: Wotschofsky Z, Gummlich L, Liep J, Stephan C, Kilic E, Jung K, Billaud J, Meyer H
    PLoS ONE, 2016;11(2):e0148746.
    Species: Human
    Sample Types: Cell Culture Supernates
  198. Mevalonate Biosynthesis Intermediates Are Key Regulators of Innate Immunity in Bovine Endometritis.
    Authors: Healey G, Collier C, Griffin S, Schuberth H, Sandra O, Smith D, Mahan S, Dieuzy-Labaye I, Sheldon I
    J Immunol, 2016;196(2):823-31.
    Species: Bovine
    Sample Types: Cell Culture Supernates
  199. Acanthamoeba castellanii (Genotype T4) Stimulates the Production of Interleukin-10 as well as Pro-inflammatory Cytokines in THP-1 Cells, Human Peripheral Blood Mononuclear Cells and Human Monocyte-Derived Macrophages
    Infect Immun, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  200. IL-17 Promotes Neutrophil-Mediated Immunity by Activating Microvascular Pericytes and Not Endothelium
    J Immunol, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  201. Combined exposure of diesel exhaust particles and respirable Soufri�re Hills volcanic ash causes a (pro-)inflammatory response in an in vitro multicellular epithelial tissue barrier model
    Authors: Ines Tomašek
    Part Fibre Toxicol, 2016;13(1):67.
    Species: Human
    Sample Types: Cell Culture Supernates
  202. Impaired anti-inflammatory action of glucocorticoid in neutrophil from patients with steroid-resistant asthma
    Respir. Res., 2016;17(1):153.
    Species: Human
    Sample Types: Cell Culture Supernates
  203. Inflammatory and immunological profiles in patients with COPD: relationship with FEV 1 reversibility
    Authors: Cleriston Farias Queiroz
    J Bras Pneumol, 2016;42(4):241-247.
    Species: Human
    Sample Types: Serum
  204. Essential Oils from Ugandan Medicinal Plants: In Vitro Cytotoxicity and Effects on IL-1?-Induced Proinflammatory Mediators by Human Gingival Fibroblasts
    Evid Based Complement Alternat Med, 2016;2016(0):5357689.
    Species: Human
    Sample Types: Cell Culture Supernates
  205. Local host response following an intramammary challenge with Staphylococcus fleurettii and different strains of Staphylococcus chromogenes in dairy heifers
    Authors: K Piccart, J Verbeke, A De Vissche, S Piepers, F Haesebrouc, S De Vlieghe
    Vet. Res., 2016;47(1):56.
    Species: Bovine
    Sample Types: Milk
  206. Short Chain Fatty Acids (SCFA) Reprogram Gene Expression in Human Malignant Epithelial and Lymphoid Cells
    PLoS ONE, 2016;11(7):e0154102.
    Species: Human
    Sample Types: Cell Culture Supernates
  207. Stand-Sit Microchip for High-Throughput, Multiplexed Analysis of Single Cancer Cells
    Sci Rep, 2016;6(0):32505.
    Applications: ChIP
  208. Mitochondrial proteins NIP-SNAP-1 and -2 are a target for the immunomodulatory activity of clarithromycin, which involves NF-?B-mediated cytokine production
    Authors: Soh Yamamoto
    Biochem. Biophys. Res. Commun, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  209. Temperature responsive porous silicon nanoparticles for cancer therapy - spatiotemporal triggering through infrared and radiofrequency electromagnetic heating
    J Control Release, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  210. Local Epidermal Growth Factor Receptor Signaling Mediates the Systemic Pathogenic Effects of Staphylococcus aureus Toxic Shock Syndrome
    PLoS ONE, 2016;11(7):e0158969.
    Species: Human
    Sample Types: Cell Culture Supernates
  211. Genetic polymorphisms of cell adhesion molecules in Behcet's disease in a Chinese Han population
    Authors: M Zheng, L Zhang, H Yu, J Hu, Q Cao, G Huang, Y Huang, G Yuan, A Kijlstra, P Yang
    Sci Rep, 2016;6(0):24974.
    Species: Human
    Sample Types: Cell Culture Supernates
  212. The Anti-inflammatory Effect of Alpha-1 Antitrypsin in Rhinovirus-infected Human Airway Epithelial Cells
    Authors: D Jiang, R Berman, Q Wu, C Stevenson, HW Chu
    J Clin Cell Immunol, 2016;7(6):.
    Species: Human
    Sample Types: Cell Culture Supernates
  213. Skin Barrier Recovery by Protease-Activated Receptor-2 Antagonist Lobaric Acid
    Authors: Jae Sung Hwang
    Biomol Ther (Seoul), 2016;24(5):529-35.
    Species: Human
    Sample Types: Cell Culture Supernates
  214. mRNA expression pattern of selected candidate genes differs in bovine oviductal epithelial cells in vitro compared with the in vivo state and during cell culture passages
    Authors: S Danesh Mes, J Sharbati, R Einspanier, C Gabler
    Reprod. Biol. Endocrinol, 2016;14(1):44.
    Species: Bovine
    Sample Types: Cell Culture Supernates
  215. A novel immunomodulatory function of neutrophils on rhinovirus-activated monocytes in vitro
    Authors: Brian G Oliver
    Thorax, 2016;71(11):1039-1049.
    Species: Human
    Sample Types: Cell Culture Supernates
  216. Intracellular RIG-I Signaling Regulates TLR4-Independent Endothelial Inflammatory Responses to Endotoxin
    J Immunol, 2016;196(11):4681-91.
    Species: Human
    Sample Types: Cell Culture Supernates
  217. The MNK-1/eIF4E pathway as a new therapeutic pathway to target inflammation and remodelling in asthma
    Cell Signal, 2016;28(10):1555-1562.
    Species: Human
    Sample Types: Cell Culture Supernates
  218. Characterization of the MMP/TIMP Imbalance and Collagen Production Induced by IL-1? or TNF-? Release from Human Hepatic Stellate Cells
    Authors: S Robert, T Gicquel, A Bodin, V Lagente, E Boichot
    PLoS ONE, 2016;11(4):e0153118.
    Species: Human
    Sample Types: Cell Culture Supernates
  219. Engineering a 3D microfluidic culture platform for tumor-treating field application
    Sci Rep, 2016;6(0):26584.
    Species: Human
    Sample Types: Cell Culture Supernates
  220. C1P Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Preventing NF-?B Activation in Neutrophils
    J Immunol, 2016;196(5):2319-26.
    Species: Human
    Sample Types: Cell Culture Supernates
  221. Differential IL-1? secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability
    Sci Rep, 2016;6(0):39035.
    Species: Human
    Sample Types: Cell Culture Supernates
  222. CREB regulates TNF-?-induced GM-CSF secretion via p38 MAPK in human lung fibroblasts
    Authors: Y Koga, T Hisada, T Ishizuka, M Utsugi, A Ono, M Yatomi, Y Kamide, H Aoki-Saito, H Tsurumaki, K Dobashi, M Yamada
    Allergol Int, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  223. Sialylation of Helicobacter bizzozeronii lipopolysaccharides modulates Toll-like receptor (TLR) 2 mediated response.
    Authors: Kondadi P, Revez J, Hanninen M, Rossi M
    Vet Res, 2015;46(0):4.
    Species: Human
    Sample Types: Cell Culture Supernates
  224. Detection and characterisation of Lactobacillus spp. in the bovine uterus and their influence on bovine endometrial epithelial cells in vitro.
    Authors: Gartner M, Bondzio A, Braun N, Jung M, Einspanier R, Gabler C
    PLoS ONE, 2015;10(3):e0119793.
    Species: Human
    Sample Types: Cell Culture Supernates
  225. The LasB Elastase of Pseudomonas aeruginosa Acts in Concert with Alkaline Protease AprA To Prevent Flagellin-Mediated Immune Recognition.
    Authors: Casilag F, Lorenz A, Krueger J, Klawonn F, Weiss S, Haussler S
    Infect Immun, 2015;84(1):162-71.
    Species: Human
    Sample Types: Cell Culture Supernates
  226. Neutrophil oxidative burst activates ATM to regulate cytokine production and apoptosis.
    Authors: Harbort C, Soeiro-Pereira P, von Bernuth H, Kaindl A, Costa-Carvalho B, Condino-Neto A, Reichenbach J, Roesler J, Zychlinsky A, Amulic B
    Blood, 2015;126(26):2842-51.
    Species: Human
    Sample Types: Cell Culture Supernates
  227. A gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, ameliorates intestinal epithelial barrier impairment partially via GPR40-MEK-ERK pathway.
    Authors: Miyamoto J, Mizukure T, Park S, Kishino S, Kimura I, Hirano K, Bergamo P, Rossi M, Suzuki T, Arita M, Ogawa J, Tanabe S
    J Biol Chem, 2015;290(5):2902-18.
    Species: Human
    Sample Types: Cell Culture Supernates
  228. Neutrophil IL-1beta processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux.
    Authors: Karmakar M, Katsnelson M, Malak H, Greene N, Howell S, Hise A, Camilli A, Kadioglu A, Dubyak G, Pearlman E
    J Immunol, 2015;194(4):1763-75.
    Species: Human
    Sample Types: Whole Cells
  229. Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production.
    Authors: Kearney C, Cullen S, Tynan G, Henry C, Clancy D, Lavelle E, Martin S
    Cell Death Differ, 2015;22(8):1313-27.
    Species: Human
    Sample Types: Cell Culture Supernates
  230. Effect of lipopolysaccharide on glucocorticoid receptor function in control nasal mucosa fibroblasts and in fibroblasts from patients with chronic rhinosinusitis with nasal polyps and asthma.
    Authors: Fernandez-Bertolin L, Mullol J, Fuentes-Prado M, Roca-Ferrer J, Alobid I, Picado C, Pujols L
    PLoS ONE, 2015;10(5):e0125443.
    Species: Human
    Sample Types: Cell Culture Supernates
  231. Macrophage activation in acute exacerbation of idiopathic pulmonary fibrosis.
    Authors: Schupp J, Binder H, Jager B, Cillis G, Zissel G, Muller-Quernheim J, Prasse A
    PLoS ONE, 2015;10(1):e0116775.
    Species: Human
    Sample Types: BALF
  232. Tumour necrosis factor receptor I blockade shows that TNF-dependent and TNF-independent mechanisms synergise in TNF receptor associated periodic syndrome.
    Authors: Fairclough L, Stoop A, Negm O, Radford P, Tighe P, Todd I
    Eur J Immunol, 2015;45(10):2937-44.
    Species: Human
    Sample Types: Cell Culture Supernates
  233. Exposure to diesel exhaust particle extracts (DEPe) impairs some polarization markers and functions of human macrophages through activation of AhR and Nrf2.
    Authors: Jaguin M, Fardel O, Lecureur V
    PLoS ONE, 2015;10(2):e0116560.
    Species: Human
    Sample Types: Cell Culture Supernates
  234. Innate immune response to Streptococcus pyogenes depends on the combined activation of TLR13 and TLR2.
    Authors: Fieber C, Janos M, Koestler T, Gratz N, Li X, Castiglia V, Aberle M, Sauert M, Wegner M, Alexopoulou L, Kirschning C, Chen Z, von Haeseler A, Kovarik P
    PLoS ONE, 2015;10(3):e0119727.
    Species: Human
    Sample Types: Cell Culture Supernates
  235. In vitro progesterone modulation on bacterial endotoxin-induced production of IL-1beta, TNFalpha, IL-6, IL-8, IL-10, MIP-1alpha, and MMP-9 in pre-labor human term placenta.
    Authors: Garcia-Ruiz G, Flores-Espinosa P, Preciado-Martinez E, Bermejo-Martinez L, Espejel-Nunez A, Estrada-Gutierrez G, Maida-Claros R, Flores-Pliego A, Zaga-Clavellina V
    Reprod Biol Endocrinol, 2015;13(0):115.
    Species: Human
    Sample Types: Cell Culture Supernates
  236. Dexamethasone induces apoptosis in pulmonary arterial smooth muscle cells.
    Authors: Price L, Shao D, Meng C, Perros F, Garfield B, Zhu J, Montani D, Dorfmuller P, Humbert M, Adcock I, Wort S
    Respir Res, 2015;16(0):114.
    Species: Human
    Sample Types: Cell Culture Supernates
  237. Role of hydrogen sulfide in paramyxovirus infections.
    Authors: Li H, Ma Y, Escaffre O, Ivanciuc T, Komaravelli N, Kelley J, Coletta C, Szabo C, Rockx B, Garofalo R, Casola A
    J Virol, 2015;89(10):5557-68.
    Species: Human
    Sample Types: Cell Culture Supernates
  238. Transcriptomic Analyses of the Biological Effects of Airborne PM2.5 Exposure on Human Bronchial Epithelial Cells.
    Authors: Zhou Z, Liu Y, Duan F, Qin M, Wu F, Sheng W, Yang L, Liu J, He K
    PLoS ONE, 2015;10(9):e0138267.
    Species: Human
    Sample Types: Cell Culture Supernates
  239. BET bromodomains regulate transforming growth factor-beta-induced proliferation and cytokine release in asthmatic airway smooth muscle.
    Authors: Perry M, Durham A, Austin P, Adcock I, Chung K
    J Biol Chem, 2015;290(14):9111-21.
    Species: Human
    Sample Types: Cell Culture Supernates
  240. Periapical fluid RANKL and IL-8 are differentially regulated in pulpitis and apical periodontitis.
    Authors: Rechenberg D, Bostanci N, Zehnder M, Belibasakis G
    Cytokine, 2014;69(1):116-9.
    Species: Human
    Sample Types: Tissue Secretion
  241. Sphingosine 1-phosphate (S1P) induced interleukin-8 (IL-8) release is mediated by S1P receptor 2 and nuclear factor kappaB in BEAS-2B cells.
    Authors: O'Sullivan M, Hirota N, Martin J
    PLoS ONE, 2014;9(4):e95566.
    Species: Human
    Sample Types: Cell Culture Supernates
  242. CD137 ligand signalling induces differentiation of primary acute myeloid leukaemia cells.
    Authors: Cheng K, Wong S, Linn Y, Ho L, Chng W, Schwarz H
    Br J Haematol, 2014;165(1):134-44.
    Species: Human
    Sample Types: Cell Culture Supernates
  243. The Toll-like receptor 4 polymorphism Asp299Gly but not Thr399Ile influences TLR4 signaling and function.
    Authors: Long H, O'Connor B, Zemans R, Zhou X, Yang I, Schwartz D
    PLoS ONE, 2014;9(4):e93550.
    Species: Human
    Sample Types: Cell Culture Supernates
  244. Role of non-coding RNAs in maintaining primary airway smooth muscle cells.
    Authors: Perry, Mark M, Tsitsiou, Eleni, Austin, Philip J, Lindsay, Mark A, Gibeon, David S, Adcock, Ian M, Chung, Kian Fan
    Respir Res, 2014;15(0):58.
    Species: Human
    Sample Types: Cell Culture Supernates
  245. Lipopolysaccharide promotes contraction of uterine myocytes via activation of Rho/ROCK signaling pathways.
    Authors: Hutchinson J, Rajagopal S, Yuan M, Norman J
    FASEB J, 2014;28(1):94-105.
    Species: Human
    Sample Types: Cell Culture Supernates
  246. Potentially pathogenic airway bacteria and neutrophilic inflammation in treatment resistant severe asthma.
    Authors: Green B, Wiriyachaiporn S, Grainge C, Rogers G, Kehagia V, Lau L, Carroll M, Bruce K, Howarth P
    PLoS ONE, 2014;9(6):e100645.
    Species: Human
    Sample Types: Sputum
  247. Lipid-modifying enzymes in human tear fluid and corneal epithelial stress response.
    Authors: Robciuc A, Rantamaki A, Jauhiainen M, Holopainen J
    Invest Ophthalmol Vis Sci, 2014;55(1):16-24.
    Species: Human
    Sample Types: Cell Culture Supernates
  248. Epithelial and stromal cells of bovine endometrium have roles in innate immunity and initiate inflammatory responses to bacterial lipopeptides in vitro via Toll-like receptors TLR2, TLR1, and TLR6.
    Authors: Turner M, Cronin J, Healey G, Sheldon I
    Endocrinology, 2014;155(4):1453-65.
    Species: Bovine
    Sample Types: Cell Culture Supernates
  249. IL-33 stimulates CXCL8/IL-8 secretion in goblet cells but not normally differentiated airway cells.
    Authors: Tanabe T, Shimokawaji T, Kanoh S, Rubin B
    Clin Exp Allergy, 2014;44(4):540-52.
    Species: Human
    Sample Types: Cell Culture Supernates
  250. Flagellin concentrations in expectorations from cystic fibrosis patients.
    Authors: Balloy V, Thevenot G, Bienvenu T, Morand P, Corvol H, Clement A, Ramphal R, Hubert D, Chignard M
    BMC Pulm Med, 2014;14(0):100.
    Species: Human
    Sample Types: Sputum
  251. A functional variant of PTPN22 confers risk for Vogt-Koyanagi-Harada syndrome but not for ankylosing spondylitis.
    Authors: Zhang Q, Qi J, Hou S, DU L, Yu H, Cao Q, Zhou Y, Liao D, Kijlstra A, Yang P
    PLoS ONE, 2014;9(5):e96943.
    Species: Human
    Sample Types: Cell Culture Supernates
  252. Porphyromonas gingivalis GroEL induces osteoclastogenesis of periodontal ligament cells and enhances alveolar bone resorption in rats.
    Authors: Lin F, Hsiao F, Huang C, Shih C, Tsao N, Tsai C, Yang S, Chang N, Hung S, Lin Y
    PLoS ONE, 2014;9(7):e102450.
    Species: Human
    Sample Types: Cell Culture Supernates
  253. TRAF5 and TRAF3IP2 gene polymorphisms are associated with Behcet's disease and Vogt-Koyanagi-Harada syndrome: a case-control study.
    Authors: Xiang Q, Chen L, Hou S, Fang J, Zhou Y, Bai L, Liu Y, Kijlstra A, Yang P
    PLoS ONE, 2014;9(1):e84214.
    Species: Human
    Sample Types: Cell Culture Supernates
  254. Pathogen sensing pathways in human embryonic stem cell derived-endothelial cells: role of NOD1 receptors.
    Authors: Reed, Daniel M, Foldes, Gabor, Gatheral, Timothy, Paschalaki, Koralia, Lendvai, Zsuzsann, Bagyura, Zsolt, Nemeth, Tamas, Skopal, Judit, Merkely, Bela, Telcian, Aurica G, Gogsadze, Leila, Edwards, Michael, Gough, Peter J, Bertin, John, Johnston, Sebastia, Harding, Sian E, Mitchell, Jane A
    PLoS ONE, 2014;9(4):e91119.
    Species: Human
    Sample Types: Cell Culture Supernates
  255. Human osteoarthritic cartilage shows reduced in vivo expression of IL-4, a chondroprotective cytokine that differentially modulates IL-1beta-stimulated production of chemokines and matrix-degrading enzymes in vitro.
    Authors: Assirelli E, Pulsatelli L, Dolzani P, Platano D, Olivotto E, Filardo G, Trisolino G, Facchini A, Borzi R, Meliconi R
    PLoS ONE, 2014;9(5):e96925.
    Species: Human
    Sample Types: Cell Culture Supernates
  256. Chinese herbal medicine suppresses invasion-promoting capacity of cancer-associated fibroblasts in pancreatic cancer.
    Authors: Chen, Lianyu, Qu, Chao, Chen, Hao, Xu, Litao, Qi, Qi, Luo, Jianmin, Wang, Kun, Meng, Zhiqiang, Chen, Zhen, Wang, Peng, Liu, Luming
    PLoS ONE, 2014;9(4):e96177.
    Species: Human
    Sample Types: Cell Culture Supernates
  257. Inflammatory and cytotoxic effects of acrolein, nicotine, acetylaldehyde and cigarette smoke extract on human nasal epithelial cells.
    Authors: Comer D, Elborn J, Ennis M
    BMC Pulm Med, 2014;14(0):32.
    Species: Human
    Sample Types: Cell Culture Supernates
  258. Integrin alphaDbeta2 (CD11d/CD18) is expressed by human circulating and tissue myeloid leukocytes and mediates inflammatory signaling.
    Authors: Miyazaki Y, Vieira-de-Abreu A, Harris E, Shah A, Weyrich A, Castro-Faria-Neto H, Zimmerman G
    PLoS ONE, 2014;9(11):e112770.
    Species: Human
    Sample Types: Cell Culture Supernates
  259. Activin A as a mediator of NK-dendritic cell functional interactions.
    Authors: Seeger P, Bosisio D, Parolini S, Badolato R, Gismondi A, Santoni A, Sozzani S
    J Immunol, 2014;192(3):1241-8.
    Species: Human
    Sample Types: Cell Culture Supernates
  260. Human intestinal epithelial cells respond to beta-glucans via Dectin-1 and Syk.
    Authors: Cohen-Kedar S, Baram L, Elad H, Brazowski E, Guzner-Gur H, Dotan I
    Eur J Immunol, 2014;44(12):3729-40.
    Species: Human
    Sample Types: Cell Culture Supernates
  261. Roles for the mitogen-activated protein kinase (MAPK) phosphatase, DUSP1, in feedback control of inflammatory gene expression and repression by dexamethasone.
    Authors: Shah S, King E, Chandrasekhar A, Newton R
    J Biol Chem, 2014;289(19):13667-79.
    Species: Human
    Sample Types: Cell Culture Supernates
  262. Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses.
    Authors: Hanuszkiewicz A, Pittock P, Humphries F, Moll H, Rosales A, Molinaro A, Moynagh P, Lajoie G, Valvano M
    J Biol Chem, 2014;289(27):19231-44.
    Species: Human
    Sample Types: Cell Culture Supernates
  263. Kineret(R)/IL-1ra blocks the IL-1/IL-8 inflammatory cascade during recombinant Panton Valentine Leukocidin-triggered pneumonia but not during S. aureus infection.
    Authors: Labrousse D, Perret M, Hayez D, da Silva S, Badiou C, Couzon F, Bes M, Chavanet P, Lina G, Vandenesch F, Croisier-Bertin D, Henry T
    PLoS ONE, 2014;9(6):e97546.
  264. Smooth muscle cells relay acute pulmonary inflammation via distinct ADAM17/ErbB axes.
    Authors: Dreymueller D, Martin C, Schumacher J, Groth E, Boehm J, Reiss L, Uhlig S, Ludwig A
    J Immunol, 2014;192(2):722-31.
    Species: Human
    Sample Types: Cell Culture Supernates
  265. IL-17A RNA aptamer: possible therapeutic potential in some cells, more than we bargained for in others?
    Authors: Doble, Rosella, McDermott, Michael, Cesur, Ozlem, Stonehouse, Nicola J, Wittmann, Miriam
    J Invest Dermatol, 2014;134(3):852-5.
    Species: Human
    Sample Types: Cell Culture Supernates
  266. TRAIL-R1 is a negative regulator of pro-inflammatory responses and modulates long-term sequelae resulting from Chlamydia trachomatis infections in humans.
    Authors: Al-Kuhlani M, Rothschild J, Pal S, de la Maza L, Ouburg S, Morre S, Dean D, Ojcius D
    PLoS ONE, 2014;9(4):e93939.
    Species: Human
    Sample Types: Cell Culture Supernates
  267. Interleukin-8 responses of multi-layer gingival epithelia to subgingival biofilms: role of the "red complex" species.
    Authors: Belibasakis G, Thurnheer T, Bostanci N
    PLoS ONE, 2013;8(12):e81581.
    Species: N/A
    Sample Types: Cell Culture Supernates
  268. Importin-7 mediates glucocorticoid receptor nuclear import and is impaired by oxidative stress, leading to glucocorticoid insensitivity.
    Authors: Hakim A, Barnes P, Adcock I, Usmani O
    FASEB J, 2013;27(11):4510-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  269. Decidual natural killer cell interactions with trophoblasts are impaired in pregnancies at increased risk of preeclampsia.
    Authors: Wallace A, Host A, Whitley G, Cartwright J
    Am J Pathol, 2013;183(6):1853-61.
    Species: Human
    Sample Types: Cell Culture Supernates
  270. Human neutrophil peptide-1 (HNP-1): a new anti-leishmanial drug candidate.
    Authors: Dabirian S, Taslimi Y, Zahedifard F, Gholami E, Doustdari F, Motamedirad M, Khatami S, Azadmanesh K, Nylen S, Rafati S
    PLoS Negl Trop Dis, 2013;7(10):e2491.
    Species: Human
    Sample Types: Cell Culture Supernates
  271. Ex vivo cytokine release and pattern recognition receptor expression of subjects exposed to dampness: pilot study to assess the outcome of mould exposure to the innate immune system.
    Authors: Punsmann S, Liebers V, Lotz A, Bruning T, Raulf M
    PLoS ONE, 2013;8(12):e82734.
    Species: Human
    Sample Types: Serum
  272. A soluble fucose-specific lectin from Aspergillus fumigatus conidia--structure, specificity and possible role in fungal pathogenicity.
    Authors: Houser J, Komarek J, Kostlanova N, Cioci G, Varrot A, Kerr S, Lahmann M, Balloy V, Fahy J, Chignard M, Imberty A, Wimmerova M
    PLoS ONE, 2013;8(12):e83077.
    Species: Human
    Sample Types: Cell Culture Supernates
  273. Leptin enhances the secretion of interleukin (IL)-18, but not IL-1beta, from human monocytes via activation of caspase-1.
    Authors: Jitprasertwong P, Jaedicke K, Nile C, Preshaw P, Taylor J
    Cytokine, 2013;65(2):222-30.
    Species: Human
    Sample Types: Cell Culture Supernates
  274. IL-27 inhibits epithelial-mesenchymal transition and angiogenic factor production in a STAT1-dominant pathway in human non-small cell lung cancer.
    Authors: Kachroo P, Lee M, Zhang L, Baratelli F, Lee G, Srivastava M, Wang G, Walser T, Krysan K, Sharma S, Dubinett S, Lee J
    J Exp Clin Cancer Res, 2013;32(0):97.
    Species: Human
    Sample Types: Cell Culture Supernates
  275. Tetra- and penta-acylated lipid A structures of Porphyromonas gingivalis LPS differentially activate TLR4-mediated NF-kappaB signal transduction cascade and immuno-inflammatory response in human gingival fibroblasts.
    Authors: Herath T, Darveau R, Seneviratne C, Wang C, Wang Y, Jin L
    PLoS ONE, 2013;8(3):e58496.
    Species: Human
    Sample Types: Cell Culture Supernates
  276. Effects of nitrous oxide on the production of cytokines and chemokines by the airway epithelium during anesthesia with sevoflurane and propofol.
    Authors: Kumakura S, Yamaguchi K, Sugasawa Y, Murakami T, Kikuchi T, Inada E, Nagaoka I
    Mol Med Rep, 2013;8(6):1643-8.
    Species: Human
    Sample Types: Epithelial Fluid
  277. 1,25-dihydroxyvitamin D3 protects against macrophage-induced activation of NFkappaB and MAPK signalling and chemokine release in human adipocytes.
    Authors: Ding C, Wilding J, Bing C
    PLoS ONE, 2013;8(4):e61707.
    Species: Human
    Sample Types: Cell Culture Supernates
  278. MicroRNA-16 affects key functions of human endothelial progenitor cells.
    Authors: Goretti E, Rolland-Turner M, Leonard F, Zhang L, Wagner D, Devaux Y
    J Leukoc Biol, 2013;93(5):645-55.
    Species: Human
    Sample Types: Cell Culture Supernates
  279. Human cytomegalovirus induces a biphasic inflammatory response in primary endothelial cells.
    Authors: Jeffery H, Soderberg-Naucler C, Butler L
    J Virol, 2013;87(11):6530-5.
    Species: Human
    Sample Types: Cell Culture Supernates
  280. S100A12 suppresses pro-inflammatory, but not pro-thrombotic functions of serum amyloid A.
    Authors: Chung Y, Goyette J, Tedla N, Hsu K, Geczy C
    PLoS ONE, 2013;8(4):e62372.
  281. Tumor necrosis factor receptor 1 associates with CD137 ligand and mediates its reverse signaling.
    Authors: Moh M, Lorenzini P, Gullo C, Schwarz H
    FASEB J, 2013;27(8):2957-66.
    Species: Human
    Sample Types: Cell Culture Supernates
  282. Selective activation of human dendritic cells by OM-85 through a NF-kB and MAPK dependent pathway.
    Authors: Parola C, Salogni L, Vaira X, Scutera S, Somma P, Salvi V, Musso T, Tabbia G, Bardessono M, Pasquali C, Mantovani A, Sozzani S, Bosisio D
    PLoS ONE, 2013;8(12):e82867.
    Species: Human
    Sample Types: Cell Culture Supernates
  283. Fibroblasts derived from human pluripotent stem cells activate angiogenic responses in vitro and in vivo.
    Authors: Shamis Y, Silva E, Hewitt K, Brudno Y, Levenberg S, Mooney D, Garlick J
    PLoS ONE, 2013;8(12):e83755.
    Species: Human
    Sample Types: Cell Culture Supernates
  284. Pentraxin 3 (PTX3) expression in allergic asthmatic airways: role in airway smooth muscle migration and chemokine production.
    Authors: Zhang J, Shan L, Koussih L, Redhu NS, Halayko AJ, Chakir J, Gounni AS
    PLoS ONE, 2012;7(4):e34965.
    Species: Human
    Sample Types: Cell Culture Supernates
  285. A novel p38-MAPK signaling axis modulates neutrophil biology in head and neck cancer.
    Authors: Dumitru CA, Fechner MK, Hoffmann TK
    J. Leukoc. Biol., 2012;91(4):591-8.
    Species: Human
    Sample Types: Cell Culture Supernates
  286. Impact of vitamin D supplementation on markers of inflammation in adults with cystic fibrosis hospitalized for a pulmonary exacerbation.
    Eur J Clin Nutr, 2012;66(9):1072-4.
    Species: Human
    Sample Types: Plasma
  287. Milk Matters: Soluble Toll-Like Receptor 2 (sTLR2) in Breast Milk Significantly Inhibits HIV-1 Infection and Inflammation.
    Authors: Henrick BM, Nag K, Yao XD
    PLoS ONE, 2012;7(7):e40138.
    Species: Human
    Sample Types: Cell Culture Supernates
  288. Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12).
    Authors: Suh HS, Choi N, Tarassishin L, Lee SC
    PLoS ONE, 2012;7(4):e35115.
    Species: Human
    Sample Types: Cell Culture Supernates
  289. IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist.
    Authors: van de Veerdonk FL, Stoeckman AK, Wu G, Boeckermann AN, Azam T, Netea MG, Joosten LA, Van der Meer JW, Hao R, Kalabokis V, Dinarello CA
    Proc. Natl. Acad. Sci. U.S.A., 2012;109(8):3001-5.
    Species: Human
    Sample Types: Cell Culture Supernates
  290. Age-related changes in expression and function of Toll-like receptors in human skin.
    Authors: Iram N, Mildner M, Prior M, Petzelbauer P, Fiala C, Hacker S, Schoppl A, Tschachler E, Elbe-Burger A
    Development, 2012;139(22):4210-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  291. Characterization and function of the human macrophage dopaminergic system: implications for CNS disease and drug abuse.
    J Neuroinflammation, 2012;9(0):203.
    Species: Human
    Sample Types: Cell Culture Supernates
  292. The role of IL-33 and its receptor ST2 in human nasal epithelium with allergic rhinitis.
    Authors: Kamekura R, Kojima T, Takano K, Go M, Sawada N, Himi T
    Clin. Exp. Allergy, 2012;42(2):218-28.
    Species: Human
    Sample Types: Cell Culture Supernates
  293. Transglutaminase is essential for IgA nephropathy development acting through IgA receptors.
    Authors: Berthelot L, Papista C, Maciel TT, Biarnes-Pelicot M, Tissandie E, Wang PH, Tamouza H, Jamin A, Bex-Coudrat J, Gestin A, Boumediene A, Arcos-Fajardo M, England P, Pillebout E, Walker F, Daugas E, Vrtosvnik F, Flamant M, Benhamou M, Cogne M, Moura IC, Monteiro RC
    J. Exp. Med., 2012;209(4):793-806.
    Species: Human
    Sample Types: Cell Culture Supernates
  294. Trappin-2/elafin modulate innate immune responses of human endometrial epithelial cells to PolyI:C.
    Authors: Drannik AG, Nag K, Yao XD, Henrick BM, Sallenave JM, Rosenthal KL
    PLoS ONE, 2012;7(4):e35866.
    Species: Human
    Sample Types: Cell Culture Supernates
  295. Hyperosmolarity-induced lipid droplet formation depends on ceramide production by neutral sphingomyelinase 2.
    Authors: Robciuc A, Hyotylainen T, Jauhiainen M, Holopainen J
    J Lipid Res, 2012;53(11):2286-95.
    Species: Human
    Sample Types: Cell Culture Supernates
  296. A disintegrin and metalloproteinase 17 (ADAM17) and epidermal growth factor receptor (EGFR) signaling drive the epithelial response to Staphylococcus aureus toxic shock syndrome toxin-1 (TSST-1).
    Authors: Breshears L, Schlievert P, Peterson M
    J Biol Chem, 2012;287(39):32578-87.
    Species: Human
    Sample Types: Cell Culture Supernates
  297. Inhibition of IL-32 activation by alpha-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model.
    Authors: Marcondes AM, Li X, Tabellini L, Bartenstein M, Kabacka J, Sale GE, Hansen JA, Dinarello CA, Deeg HJ
    Blood, 2011;118(18):5031-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  298. Plasma levels of procalcitonin and eight additional inflammatory molecules in febrile neutropenic patients.
    Authors: Neuenschwander LC, Bittencourt H, Ribeiro AF, Teixeira AL, Teixeira MM, Teixeira JC, Nobre V
    Clinics (Sao Paulo), 2011;66(10):1699-705.
    Species: Human
    Sample Types: Plasma
  299. Dysregulation of TIM-3-Galectin-9 Pathway in the Cystic Fibrosis Airways.
    Authors: Vega-Carrascal I, Reeves EP, Niki T, Arikawa T, McNally P, O'Neill SJ, Hirashima M, McElvaney NG
    J. Immunol., 2011;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  300. Epidermal growth factor receptor reactivation induced by E-prostanoid-3 receptor- and tumor necrosis factor-alpha-converting enzyme-dependent feedback exaggerates interleukin-8 production in airway cancer (NCI-H292) cells.
    Authors: Kim S, Lewis C, Nadel JA
    Exp. Cell Res., 2011;317(18):2650-60.
    Species: Human
    Sample Types: Cell Culture Supernates
  301. IL-8 dictates glycosaminoglycan binding and stability of IL-18 in cystic fibrosis.
    Authors: Reeves EP, Williamson M, Byrne B, Bergin DA, Smith SG, Greally P, O'Kennedy R, O'Neill SJ, McElvaney NG
    J. Immunol., 2010;184(3):1642-52.
    Species: Human
    Sample Types: Serum
  302. Human uterine epithelial cell secretions regulate dendritic cell differentiation and responses to TLR ligands.
    Authors: Ochiel DO, Ghosh M, Fahey JV
    J. Leukoc. Biol., 2010;88(3):435-44.
    Species: Human
    Sample Types: Cell Culture Supernates
  303. Activation of platelets by Aspergillus fumigatus and potential role of platelets in the immunopathogenesis of Aspergillosis.
    Authors: Rodland EK, Ueland T, Pedersen TM, Halvorsen B, Muller F, Aukrust P, Froland SS
    Infect. Immun., 2010;78(3):1269-75.
    Species: Human
    Sample Types: Cell Culture Supernates
  304. Iris pigment epithelial cells express a functional lipopolysaccharide receptor complex.
    Authors: Chui JJ, Li MW, Di Girolamo N, Chang JH, McCluskey PJ, Wakefield D
    Invest. Ophthalmol. Vis. Sci., 2010;51(5):2558-67.
    Species: Human
    Sample Types: Cell Culture Supernates
  305. Vascular endothelial growth factor induces protein kinase D-dependent production of proinflammatory cytokines in endothelial cells.
    Authors: Hao Q, Wang L, Tang H
    Am. J. Physiol., Cell Physiol., 2009;296(4):C821-7.
    Species: Human
    Sample Types: Cell Culture Supernates
  306. Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women.
    Authors: Hawn TR, Scholes D, Wang H, Li SS, Stapleton AE, Janer M, Aderem A, Stamm WE, Zhao LP, Hooton TM
    PLoS ONE, 2009;4(12):e8300.
    Species: Human
    Sample Types: Urine
  307. Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA.
    Authors: Kinoshita H, Takai T, Le TA, Kamijo S, Wang XL, Ushio H, Hara M, Kawasaki J, Vu AT, Ogawa T, Gunawan H, Ikeda S, Okumura K, Ogawa H
    J. Allergy Clin. Immunol., 2009;123(1):179-86.
    Species: Human
    Sample Types: Cell Culture Supernates
  308. Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses.
    Authors: Wang Q, Nagarkar DR, Bowman ER, Schneider D, Gosangi B, Lei J, Zhao Y, McHenry CL, Burgens RV, Miller DJ, Sajjan U, Hershenson MB
    J. Immunol., 2009;183(11):6989-97.
    Species: Human
    Sample Types: Cell Culture Supernates
  309. Abnormalities in serum chemokine levels in euthymic patients with bipolar disorder.
    Authors: Brietzke E, Kauer-Sant'Anna M, Teixeira AL, Kapczinski F
    Brain Behav. Immun., 2009;23(8):1079-82.
    Species: Human
    Sample Types: Serum
  310. IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytes via increased IL-22 receptor expression.
    Authors: Tohyama M, Hanakawa Y, Shirakata Y, Dai X, Yang L, Hirakawa S, Tokumaru S, Okazaki H, Sayama K, Hashimoto K
    Eur. J. Immunol., 2009;39(10):2779-88.
    Species: Human
    Sample Types: Cell Culture Supernates
  311. Carbon dioxide inhalation causes pulmonary inflammation.
    Authors: Abolhassani M, Guais A, Chaumet-Riffaud P, Sasco AJ, Schwartz L
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009;296(4):L657-65.
    Species: Human
    Sample Types: Cell Culture Supernates
  312. Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells.
    Authors: Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G
    Circulation, 2009;119(10):1424-32.
    Species: Human
    Sample Types: Cell Culture Supernates
  313. Inorganic arsenic activates reduced NADPH oxidase in human primary macrophages through a Rho kinase/p38 kinase pathway.
    Authors: Lemarie A, Bourdonnay E, Morzadec C, Fardel O, Vernhet L
    J. Immunol., 2008;180(9):6010-7.
    Species: Human
    Sample Types: Cell Culture Supernates
  314. Impact of tobacco-smoke on key signaling pathways in the innate immune response in lung macrophages.
    Authors: Birrell MA, Wong S, Catley MC, Belvisi MG
    J. Cell. Physiol., 2008;214(1):27-37.
    Species: Human
    Sample Types: Cell Culture Supernates
  315. Reduced response to adiponectin and lower abundance of adiponectin receptor proteins in type 2 diabetic monocytes.
    Authors: Weigert J, Neumeier M, Wanninger J, Wurm S, Kopp A, Schober F, Filarsky M, Schaffler A, Zeitoun M, Aslanidis C, Buechler C
    FEBS Lett., 2008;582(12):1777-82.
    Species: Human
    Sample Types: Cell Culture Supernates
  316. Adenosine receptors in regulation of dendritic cell differentiation and function.
    Authors: Novitskiy SV, Ryzhov S, Zaynagetdinov R, Goldstein AE, Huang Y, Tikhomirov OY, Blackburn MR, Biaggioni I, Carbone DP, Feoktistov I, Dikov MM
    Blood, 2008;112(5):1822-31.
    Species: Human
    Sample Types: Cell Culture Supernates
  317. Fungal proteases induce Th2 polarization through limited dendritic cell maturation and reduced production of IL-12.
    Authors: Lamhamedi-Cherradi SE, Martin RE, Ito T, Kheradmand F, Corry DB, Liu YJ, Moyle M
    J. Immunol., 2008;180(9):6000-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  318. Lactoferrin, a major defense protein of innate immunity, is a novel maturation factor for human dendritic cells.
    Authors: Spadaro M, Caorsi C, Ceruti P, Varadhachary A, Forni G, Pericle F, Giovarelli M
    FASEB J., 2008;22(8):2747-57.
    Species: Human
    Sample Types: Cell Culture Supernates
  319. Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea.
    Authors: Yamasaki K, Di Nardo A, Bardan A, Murakami M, Ohtake T, Coda A, Dorschner RA, Bonnart C, Descargues P, Hovnanian A, Morhenn VB, Gallo RL
    Nat. Med., 2007;13(8):975-80.
    Species: Human
    Sample Types: Cell Culture Supernates
  320. Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging.
    Authors: Yang SR, Wright J, Bauter M, Seweryniak K, Kode A, Rahman I
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007;292(2):L567-76.
    Species: Human
    Sample Types: Cell Culture Supernates
  321. A synthetic analog of alpha-galactosylceramide induces macrophage activation via the TLR4-signaling pathways.
    Authors: Hung LC, Lin CC, Hung SK, Wu BC, Jan MD, Liou SH, Fu SL
    Biochem. Pharmacol., 2007;73(12):1957-70.
    Species: Human
    Sample Types: Cell Culture Supernates
  322. Respiratory effects of exposure to diesel traffic in persons with asthma.
    Authors: McCreanor J, Cullinan P, Nieuwenhuijsen MJ, Stewart-Evans J, Malliarou E, Jarup L, Harrington R, Svartengren M, Han IK, Ohman-Strickland P, Chung KF, Zhang J
    N. Engl. J. Med., 2007;357(23):2348-58.
    Species: Human
    Sample Types: Sputum
  323. Enhanced IL-1beta-induced IL-8 production in cystic fibrosis lung epithelial cells is dependent of both mitogen-activated protein kinases and NF-kappaB signaling.
    Authors: Muselet-Charlier C, Roque T, Boncoeur E, Chadelat K, Clement A, Jacquot J, Tabary O
    Biochem. Biophys. Res. Commun., 2007;357(2):402-7.
    Species: Human
    Sample Types: Cell Culture Supernates
  324. Guinea pig neutrophils infected with Mycobacterium tuberculosis produce cytokines which activate alveolar macrophages in noncontact cultures.
    Authors: Sawant KV, McMurray DN
    Infect. Immun., 2007;75(4):1870-7.
    Species: Guinea Pig
    Sample Types: Cell Culture Supernates
  325. Mesenchymal stem cells support migration, extracellular matrix invasion, proliferation, and survival of endothelial cells in vitro.
    Authors: Potapova IA, Gaudette GR, Brink PR, Robinson RB, Rosen MR, Cohen IS, Doronin SV
    Stem Cells, 2007;25(7):1761-8.
    Species: Human
    Sample Types: Cell Culture Supernates
  326. The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis.
    Authors: Sa SM, Valdez PA, Wu J
    J. Immunol., 2007;178(4):2229-40.
    Species: Human
    Sample Types: Cell Culture Supernates
  327. Novel role for the liver X nuclear receptor in the suppression of lung inflammatory responses.
    Authors: Birrell MA, Catley MC, Hardaker E, Wong S, Willson TM, McCluskie K, Leonard T, Farrow SN, Collins JL, Haj-Yahia S, Belvisi MG
    J. Biol. Chem., 2007;282(44):31882-90.
    Species: Human
    Sample Types: Cell Culture Supernates
  328. Airway remodelling in children with cystic fibrosis.
    Authors: Hilliard TN, Regamey N, Shute JK, Nicholson AG, Alton EW, Bush A, Davies JC
    Thorax, 2007;62(12):1074-80.
    Species: Human
    Sample Types: BALF
  329. Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling.
    Authors: Weindl G, Naglik JR, Kaesler S, Biedermann T, Hube B, Korting HC, Schaller M
    J. Clin. Invest., 2007;117(12):3664-3672.
    Species: Human
    Sample Types: Cell Culture Supernates
  330. NF-kappaB in tracheal lavage fluid from intubated premature infants: association with inflammation, oxygen, and outcome.
    Authors: Bourbia A, Cruz MA, Rozycki HJ
    Arch. Dis. Child. Fetal Neonatal Ed., 2006;91(1):F36-9.
    Species: Human
    Sample Types: Tracheal Lavage Fluid
  331. Toll-like receptor 2, 3, and 4 expression and function in human airway smooth muscle.
    Authors: Sukkar MB, Xie S, Khorasani NM, Kon OM, Stanbridge R, Issa R, Chung KF
    J. Allergy Clin. Immunol., 2006;118(3):641-8.
    Species: Human
    Sample Types: Cell Culture Supernates
  332. Development of a guinea pig immune response-related microarray and its use to define the host response following Mycobacterium bovis BCG vaccination.
    Authors: Tree JA, Elmore MJ, Javed S, Williams A, Marsh PD
    Infect. Immun., 2006;74(2):1436-41.
    Species: Guinea Pig
    Sample Types: Cell Culture Supernates
  333. Role of matrix metalloproteinases in the inflammatory response in human airway cell-based assays and in rodent models of airway disease.
    Authors: Birrell MA, Wong S, Dekkak A, De Alba J, Haj-Yahia S, Belvisi MG
    J. Pharmacol. Exp. Ther., 2006;318(2):741-50.
    Species: Human
    Sample Types: Cell Culture Supernates
  334. Modulation of neonatal microbial recognition: TLR-mediated innate immune responses are specifically and differentially modulated by human milk.
    Authors: LeBouder E, Rey-Nores JE, Raby AC, Affolter M, Vidal K, Thornton CA, Labeta MO
    J. Immunol., 2006;176(6):3742-52.
    Species: Human
    Sample Types: Cell Culture Supernates
  335. Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists.
    Authors: Fritz JH, Girardin SE, Fitting C, Werts C, Mengin-Lecreulx D, Caroff M, Cavaillon JM, Philpott DJ, Adib-Conquy M
    Eur. J. Immunol., 2005;35(8):2459-70.
    Species: Human
    Sample Types: Cell Culture Supernates
  336. Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments.
    Authors: Oynebraten I, Bakke O, Brandtzaeg P, Johansen FE, Haraldsen G
    Blood, 2004;104(2):314-20.
    Species: Human
    Sample Types: Cell Culture Supernates
  337. IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate.
    Authors: Miranda-Carus ME, Balsa A, Benito-Miguel M, Perez de Ayala C, Martin-Mola E
    J. Immunol., 2004;173(2):1463-76.
    Species: Human
    Sample Types: Cell Culture Supernates
  338. Urinary interleukin-8 predicts the response of standard and low dose intravesical bacillus Calmette-Guerin (modified Danish 1331 strain) for superficial bladder cancer.
    Authors: Kumar A, Dubey D, Bansal P, Mandhani A, Naik S
    J. Urol., 2002;168(5):2232-5.
    Species: Human
    Sample Types: Urine
  339. Mycobacterium bovis BCG vaccination augments interleukin-8 mRNA expression and protein production in guinea pig alveolar macrophages infected with Mycobacterium tuberculosis.
    Authors: Lyons MJ, Yoshimura T, McMurray DN
    Infect. Immun., 2002;70(10):5471-8.
    Species: Guinea Pig
    Sample Types: Cell Culture Supernates
  340. Methoxyluteolin Inhibits Neuropeptide-stimulated Proinflammatory Mediator Release via mTOR Activation from Human Mast Cells.
    Authors: Patel A, Theoharides T
    J Pharmacol Exp Ther, 0;361(3):462-471.
    Species: Human
    Sample Types: Cell Culture Supernates
  341. Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients.
    Authors: Bellini A, Marini MA, Bianchetti L, Barczyk M, Schmidt M, Mattoli S
    Mucosal Immunol, 0;5(2):140-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  342. Soluble forms of Toll-like receptor (TLR)2 capable of modulating TLR2 signaling are present in human plasma and breast milk.
    Authors: LeBouder E, Rey-Nores J, Rushmere N, Grigorov M, Lawn S, Affolter M, Griffin G, Ferrara P, Schiffrin E, Morgan B, Labeta M
    J Immunol, 0;171(12):6680-9.
    Species: Human
    Sample Types: Cell Culture Supernates

FAQs

  1. Is PBS a suitable alternative with which to formulate the Reagent Diluent?

    • Our lab has determined that Tris-buffered saline generates optimal assay performance in comparison to PBS for this assay. This assay is validated with Reagent Diluent formulated using Tris-buffered saline.

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Reviews for Human IL-8/CXCL8 DuoSet ELISA

Average Rating: 4.7 (Based on 21 Reviews)

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Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 12/13/2021
Sample Tested: Plasma

Good results in plasma. Used neat and 1:5.


Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 11/30/2021
Sample Tested: Serum-free Cell Culture Supernates

Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 04/29/2021
Sample Tested: Cell culture supernatant

Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 01/27/2021
Sample Tested: Cell culture supernatant

Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 05/01/2020
Sample Tested: Primary airway epithelial cells

Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 04/02/2020
Sample Tested: Serum and Plasma

We used this kit for the quantification of IL-8 in human serum and plasma. We could not see any signals. Nevertheless, well-explained protocol.


Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 01/25/2020
Sample Tested: Cell Culture Media

Human IL-8/CXCL8 DuoSet ELISA
By sothy yi on 12/11/2019
Sample Tested: human whole blood

Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 09/14/2019
Sample Tested: HUVEC human umbilical vein endothelial cells

Total Cell Protein


Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 09/07/2019
Sample Tested: Cell culture supernatant,Stimulated Human Bronchial Epithelial Cell Line (BEAS-2B)

Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 08/01/2019
Sample Tested: Tissue Culture Media

Human IL-8/CXCL8 DuoSet ELISA
By Sophie Millar on 01/16/2019
Sample Tested: Cell Culture Media

Human IL-8/CXCL8 DuoSet ELISA
By Ivan Luzardo on 01/03/2019
Sample Tested: Cell Lysates

Human IL-8/CXCL8 DuoSet ELISA
By Leslie Priddy on 03/30/2018
Sample Tested: Serum

Human IL-8/CXCL8 DuoSet ELISA
By Balaji Mahender on 01/18/2018
Sample Tested: Citrate Plasma,EDTA Plasma,Heparin Plasma

Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 08/02/2017
Sample Tested: Serum and Plasma

Human CXCL8/IL-8 DuoSet ELISA
By Anonymous on 08/19/2016
Sample Tested: HUVEC human umbilical vein endothelial cells

Human CXCL8/IL-8 DuoSet ELISA
By sothy yi on 08/02/2016
Sample Tested: THP-1 human acute monocytic leukemia cell line

Human CXCL8/IL-8 DuoSet ELISA
By Anonymous on 06/02/2016
Sample Tested: HUVEC human umbilical vein endothelial cells

Very nice IL8 detection in HUVEC cells treated with pro-inflammatory stimuli. Slightly higher background in untreated cells than expected, but not overly problematic. Would definitely publish and use again.


Human CXCL8/IL-8 DuoSet ELISA
By Yu Sun on 05/24/2016
Sample Tested: Human cell conditioned medium

Human CXCL8/IL-8 DuoSet ELISA, 15 Plate
By Yanhan Wang on 02/25/2016
Sample Tested: NHEK human normal epidermal keratinocytes