Human Integrin beta 2/CD18 Antibody
Human Integrin beta 2/CD18 Antibody Summary
Gln23-Asn700
Accession # AAA59490
Complete Your Research
Complete Your Experiment
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
View Larger
Integrin beta 2/CD18 in Human PBMCs. Integrin beta 2/CD18 was detected in immersion fixed human peripheral blood mononuclear cells (PBMCs) using 10 µg/mL Goat Anti-Human Integrin beta 2/CD18 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1730) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # NL001) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Non-adherent Cells.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Integrin beta 2/CD18
Integrin beta 2 is a transmembrane protein expressed by all leukocytes. It occurs in heterodimeric complexes with Integrin subunits alpha D, alpha L (complex also known as LFA‑1), alpha M (Mac-1), or alpha X (CR-4). These complexes are important in adhesion and leukocyte trafficking.
Product Datasheets
Citations for Human Integrin beta 2/CD18 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
11
Citations: Showing 1 - 10
Filter your results:
Filter by:
-
The metabolism of cells regulates their sensitivity to NK cells depending on p53 status
Authors: S Belkahla, JM Brualla, A Fayd'herbe, P Falvo, N Allende-Ve, M Constantin, AUH Khan, L Coenon, C Alexia, G Mitola, P Massa, S Orecchioni, F Bertolini, W Mnif, J Hernandez, A Anel, M Villalba
Scientific Reports, 2022;12(1):3234.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Metformin sensitizes leukemic cells to cytotoxic lymphocytes by increasing expression of intercellular adhesion molecule-1 (ICAM-1)
Authors: N Allende-Ve, J Marco Brua, P Falvo, C Alexia, M Constantin, AF de Maudave, L Coenon, D Gitenay, G Mitola, P Massa, S Orecchioni, F Bertolini, I Marzo, A Anel, M Villalba
Scientific Reports, 2022;12(1):1341.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Hepatocytes Delete Regulatory T Cells by Enclysis, a CD4+ T Cell Engulfment Process
Authors: SP Davies, GM Reynolds, AL Wilkinson, X Li, R Rose, M Leekha, YS Liu, R Gandhi, E Buckroyd, J Grove, NM Barnes, RC May, SG Hubscher, DH Adams, Y Huang, O Qureshi, Z Stamataki
Cell Rep, 2019;29(6):1610-1620.e4.
Species: Human
Sample Types: Whole Cells
Applications: IF -
The Extracellular Domain of the β2 Integrin β Subunit (CD18) Is Sufficient for Escherichia coli Hemolysin and Aggregatibacter actinomycetemcomitans Leukotoxin Cytotoxic Activity
Authors: LC Ristow, V Tran, KJ Schwartz, L Pankratz, A Mehle, JD Sauer, RA Welch
MBio, 2019;10(4):.
Species: Human
Sample Types: Protein
Applications: Western Blot -
Biomimetic post-capillary venule expansions for leukocyte adhesion studies
Authors: BL Benson, L Li, JT Myers, RD Dorand, UA Gurkan, AY Huang, RM Ransohoff
Sci Rep, 2018;8(1):9328.
-
Synthesis of Human Neutrophil Extracellular Traps Contributes to Angiopoietin-Mediated In Vitro Proinflammatory and Proangiogenic Activities
Authors: SS Lavoie, E Dumas, B Vulesevic, PE Neagoe, M White, MG Sirois
J. Immunol., 2018;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Bystander cells enhance NK cytotoxic efficiency by reducing search time
Authors: X Zhou, R Zhao, K Schwarz, M Mangeat, EC Schwarz, M Hamed, I Bogeski, V Helms, H Rieger, B Qu
Sci Rep, 2017;7(0):44357.
Species: Human
Sample Types: Whole Cells
Applications: Migration Assay -
An anti-inflammatory property of Candida albicans beta-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism.
Authors: Smeekens S, Gresnigt M, Becker K, Cheng S, Netea S, Jacobs L, Jansen T, van de Veerdonk F, Williams D, Joosten L, Dinarello C, Netea M
Cytokine, 2015;71(2):215-22.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Mesenchymal stem cell contact promotes CCN1 splicing and transcription in myeloma cells.
Authors: Dotterweich J, Ebert R, Kraus S, Tower R, Jakob F, Schutze N
Cell Commun Signal, 2014;12(0):36.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Complement Receptor Mac-1 Is an Adaptor for NB1 (CD177)-mediated PR3-ANCA Neutrophil Activation.
Authors: Jerke U, Rolle S, Dittmar G, Bayat B, Santoso S, Sporbert A, Luft F, Kettritz R
J. Biol. Chem., 2011;286(9):7070-81.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Inflammatory cytokines stimulate the adhesion of colon carcinoma cells to mesothelial monolayers.
Authors: van Grevenstein WM, Hofland LJ, van Rossen ME, van Koetsveld PM, Jeekel J, van Eijck CH
Dig. Dis. Sci., 2007;52(10):2775-83.
Species: Human
Sample Types: Whole Cells
Applications: ICC
FAQs
No product specific FAQs exist for this product, however you may
View all Antibody FAQsIsotype Controls
Reconstitution Buffers
Secondary Antibodies
Reviews for Human Integrin beta 2/CD18 Antibody
There are currently no reviews for this product. Be the first to review Human Integrin beta 2/CD18 Antibody and earn rewards!
Have you used Human Integrin beta 2/CD18 Antibody?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
