Human Mineralocorticoid R/NR3C2 Antibody
Human Mineralocorticoid R/NR3C2 Antibody Summary
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
Background: Mineralocorticoid R/NR3C2
Mineralcorticoid Receptor (MR; NR3C2) is a member of the Steroid Receptor superfamily (AR,ER,GR,PR). Aldosterone binds to MR with a high affinity. MR is expressed in the kidney, gut, brain, pituitary, hypothalamus and heart. MR plays a critical role in regulating electrolyte and fluid balance in the kidney, as well as having specific roles in the central nervous system. The protein is expressed as a 107 kDa nuclear form. MR and GR can cooperatively form heterodimers.
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Cell and Tissue Staining Kits
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