Human NF-H Antibody

Catalog # Availability Size / Price Qty
MAB31083-100
MAB31083-SP

Save 15% on Select RUO Reagents. See Details

Detection of NF‑H in Human Brain Cerebellum.
3 Images
Product Details
FAQs
Supplemental Products
Reviews

Human NF-H Antibody Summary

Species Reactivity
Human
Specificity
Detects Human and Bovine NF-H in direct ELISA.
Source
Monoclonal Mouse IgG1 Clone # 1053309
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Natural Neurofilament H (200 kD) Bovine Protein
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Immunohistochemistry
3-25 µg/mL
Immersion fixed paraffin-embedded sections of human brain cerebellum
Immunocytochemistry
8-25 µg/mL
Immersion fixed HeLa (positive), K562 (negative) cells and Raji (negative) cells.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunohistochemistry View Larger

Detection of NF‑H in Human Brain Cerebellum. NF‑H was detected in immersion fixed paraffin-embedded sections of human brain cerebellum using Mouse Anti-Human NF‑H Monoclonal Antibody (Catalog # MAB31083) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Mouse IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC001). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using VisUCyte Antigen Retrieval Reagent-Basic (Catalog # VCTS021). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm in Purkinjie neurons. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Immunocytochemistry View Larger

Detection of NF‑H in HeLa human cervical epithelial carcinoma cell line (positive) and Raji human Burkitt's lymphoma cell line (negative) cells. NF‑H was detected in immersion fixed HeLa human cervical epithelial carcinoma cell line (positive) and Raji human Burkitt's lymphoma cell line (negative) cells using Mouse Anti-Human NF‑H Monoclonal Antibody (Catalog # MAB31083) at 8 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Immunocytochemistry View Larger

Detection of NF‑H in K562 Human Chronic Myelogenous Leukemia Cell Line (Positive) and Raji Human Burkitt's Lymphoma Cell Line (Negative) Cells. NF‑H was detected in immersion fixed K562 Human Chronic Myelogenous Leukemia Cell Line (Positive) and Raji Human Burkitt's Lymphoma Cell Line (Negative) Cells using Mouse Anti-Human NF‑H Monoclonal Antibody (Catalog # MAB31083) at 8 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. View our protocol for Fluorescent ICC Staining of Non-adherent Cells.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
Loading...
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: NF-H

The human Neurofilament Heavy chain, also known as NF-H and NEFH, is a phosphorylated cytoskeletal intermediate filament protein that is expressed in neurons. Neurofilaments are trimers that always contain the 68 kDa NF-L and variably contain 125 kDa NF-M and 200 kDa NF-H. In the region used for immunization, mouse and rat NF-H are each 93% identical to human NF-H.

Long Name
Neurofilament Protein, Heavy Chain
Entrez Gene IDs
4744 (Human)
Alternate Names
200 kDa neurofilament protein; KIAA0845; NEFH; Neurofilament Heavy (200kDa); neurofilament heavy polypeptide; Neurofilament triplet H protein; neurofilament, heavy polypeptide 200kDa; neurofilament, heavy polypeptide; NF200; NFH; NF-H

Product Datasheets

You must select a language.

x

FAQs

No product specific FAQs exist for this product, however you may

View all Antibody FAQs
Loading...

Reviews for Human NF-H Antibody

There are currently no reviews for this product. Be the first to review Human NF-H Antibody and earn rewards!

Have you used Human NF-H Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review