Human Serpin I2 Antibody

Catalog # Availability Size / Price Qty
MAB2235
MAB2235-SP
Product Details
Citations (1)
FAQs
Supplemental Products
Reviews

Human Serpin I2 Antibody Summary

Species Reactivity
Human
Specificity
Detects human Serpin I2 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human Serpin A1, A3, A4, A5, C1, F2, I1, recombinant mouse (rm) Serpin D1, or rmPEDF is observed.
Source
Monoclonal Mouse IgG2A Clone # 203402
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Serpin I2
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Human Serpin I2
Immunoprecipitation
25 µg/mL
Conditioned cell culture medium spiked with Recombinant Human Serpin I2, see our available Western blot detection antibodies

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Availability
Size / Price
Qty
RB01
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Serpin I2

Serpin I2, also known as PI14 (proteinase inhibitor 14), pancipin or MEPI (myoepithelium-derived serine proteinase inhibitor), is an inhibitor of cell motility and metastasis and is a type 2 tumor suppressor.

Entrez Gene IDs
5276 (Human)
Alternate Names
MEPI; MEPIpancpin; Myoepithelium-derived serine protease inhibitor; Pancipin; Pancpin; Pancreas-specific protein TSA2004; Peptidase inhibitor 14; PI14; PI-14; PI14clade I (neuroserpin), member 2; protease inhibitor 14; serine (or cysteine) proteinase inhibitor, clade I (pancpin), member 2; Serpin I2; serpin peptidase inhibitor, clade I (pancpin), member 2; SERPIN12

Product Datasheets

Citation for Human Serpin I2 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. SerpinI2 (pancpin) is an inhibitory serpin targeting pancreatic elastase and chymotrypsin
    Authors: Wayne J Higgins
    Biochim. Biophys. Acta, 2017;1865(2):195-200.
    Applications: Immunoprecipitation

FAQs

No product specific FAQs exist for this product, however you may

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Isotype Controls

Mouse IgG2A Isotype Control

Reconstitution Buffers

Secondary Antibodies

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