Detection of SSTR3 in PC‑3 Human Cell Line by Flow Cytometry.
PC‑3 human prostate cancer cell line was stained with Mouse Anti-Human Somatostatin R3/ SSTR3 Monoclonal Antibody (Catalog # MAB7018, filled histogram) or isotype control antibody (Catalog # MAB003, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B).
Preparation and Storage
Sterile PBS to a final concentration of 0.5 mg/mL.
Reconstitution Buffer Available
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Somatostatin R3/SSTR3
Somatostatin Receptor 3 (SSTR3) is one of five 7-transmembrane G-protein-coupled receptors for somatostatins 14 and 28. Human SSTR3 shares 80% aa identity with mouse SSTR3 within the extracellular domains. SSTR3 protein has been detected in anterior pituitary, lymphocytes, thyroid, parathyroid, stomach, small intestine, and pancreatic islets. In neurons, it is located within cilia and is implicated in object recognition memory. It is an inhibitory receptor that transduces the antiproliferative and antisecretive effects of somatostatins in the pituitary.
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