Human TEM5/GPR124 Antibody Summary
Accession # Q96PE1
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Detection of TEM5/GPR124 in HEK293 Human Cell Line Transfected with Human TEM5/GPR124 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with human TEM5/GPR124 and eGFP was stained with either (A) Mouse Anti-Human TEM5/GPR124 Monoclonal Antibody (Catalog # MAB8896) or (B) Mouse IgG2B Flow Cytometry Isotype Control (Catalog # MAB0041) followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B).
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
G protein-coupled receptor 124 (GPR124, also known as TEM5), is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. GPR124 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. This receptor mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans. GPR124 has also been shown to interact with DLG1 through its PDZ-binding motif.
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