Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Western Blot

Cited:

Immunocytochemistry

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all Thymopoietin Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human Thymopoietin
Pro2-Gln187

Specificity

Detects human Thymopoietin in direct ELISAs and Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human Thymopoietin Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Human Thymopoietin

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Thymopoietin

Thymopoietin (TP alpha; also TMPO, LAP2 alpha and TPRP alpha ) is a 75 kDa member of the LEM family of molecules.  It is a nucleoplasmic protein that is widely expressed in cells such as keratinocytes and thymocytes.  Here, it interacts with A-type lamins and Rb/retinoblastoma protein, thus participating in cell cycle exit.  Human thymopoietin is 694 amino acids (aa) in length.  It contains a potential N-terminal “thymopoietin peptide” segment (aa #2-49), a BAF-binding LEM domain (aa #109-153), an NLS (aa #190-196), and a coiled-coil region (aa #558-657).  Multiple splice variants exist.  All contain the same 188 N-terminal amino acids.  Five variants show singular 49, 157, 266, 226, and 60 aa substitutions for the C-terminal 506 amino acids.  Over aa #2-187, human thymopoietin shares 93% aa identity with mouse thymopoietin.

Alternate Names

TMPO

Entrez Gene IDs

7112 (Human)

Gene Symbol

TMPO

Additional Thymopoietin Products

Product Documents for Human Thymopoietin Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human Thymopoietin Antibody

For research use only

Citations for Human Thymopoietin Antibody

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