Human TMPRSS2 Antibody

Catalog #: MAB107231 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
Detection of TMPRSS2 in HEK293 Human Cell Line Transfected with Human TMPRSS2 and eGFP by Flow Cytometry.
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Product Details
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Human TMPRSS2 Antibody Summary

Species Reactivity
Detects human TMPRSS2 in direct ELISAs.
Monoclonal Mouse IgG2B Clone # 1038105
Protein A or G purified from hybridoma culture supernatant
Human TMPRSS2 synthetic peptide
Accession # O15393
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

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Recommended Concentration
Flow Cytometry
0.25 µg/106 cells
HEK293 Human Cell Line Transfected with Human TMPRSS2 and eGFP

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry View Larger

Detection of TMPRSS2 in HEK293 Human Cell Line Transfected with Human TMPRSS2 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with (A) human TMPRSS2 or (B) irrelevant protein, and eGFP was stained with Mouse Anti-Human TMPRSS2 Monoclonal Antibody (Catalog # MAB107231) followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (F0101B). Quadrant markers were set based on control antibody staining (MAB0041). Staining was performed using our Staining Membrane-associated Proteins protocol.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Preparation and Storage

Reconstitute at 0.5 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: TMPRSS2

TMPRSS2 belongs to the serine protease family. It contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. TMPRSS2 facilitates human SARS coronavirus (SARS-CoV) infection via two independent mechanisms: proteolytic cleavage of ACE2, which might promote viral uptake, and cleavage of coronavirus spike glycoprotein, which activates the glycoprotein for cathepsin Lindependent host cell entry. Alternatively spliced transcripts encoding different proteins have been described.

Long Name
Transmembrane protease, serine 2
Entrez Gene IDs
7113 (Human); 50528 (Mouse); 102137447 (Cynomolgus Monkey)
Alternate Names
EC 3.4.21; Epitheliasin; FLJ41954; NP_001128571.1; NP_001369649.1; NP_005647.3; PP9284; PRSS10; Serine protease 10; TMPRSS2; transmembrane protease serine 2; transmembrane protease, serine 2

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Isotype Controls

Reconstitution Buffers

Secondary Antibodies

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