Human TNF-alpha Quantikine HS ELISA

Newer Version Available: HSTA00E

Discontinued Product

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TNF-alpha ELISA Kit ELISA
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Product Details
Procedure
Citations (139)
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Human TNF-alpha Quantikine HS ELISA Summary

Assay Length
6.5 hours
Sample Type & Volume Required Per Well
Serum (200 uL), EDTA Plasma (200 uL), Heparin Plasma (200 uL), Citrate Plasma (200 uL)
Sensitivity
0.191 pg/mL
Assay Range
0.5 - 32 pg/mL (Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma)
Specificity
Natural and recombinant human TNF-alpha
Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
Interference
No significant interference observed with available related molecules.

Product Summary

The Quantikine HS Human TNF-alpha Immunoassay is a 6.5 hour solid phase ELISA designed to measure TNF-alpha in serum and plasma. It contains E. coli-derived recombinant human TNF-alpha and antibodies raised against the recombinant factor. It has been shown to accurately quantitate recombinant human TNF-alpha. Results obtained with naturally occurring TNF-alpha samples showed linear curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit can be used to determine relative mass values for natural TNF-alpha. Since the measurement of TNF-alpha is insensitive to the addition of recombinant forms of either of the two types of soluble receptors, it is probable that this measurement detects the total amount of TNF-alpha in samples, i.e., the total amount of free TNF-alpha plus the amount of TNF-alpha bound to soluble receptors.

Precision

Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision. Assays were performed by at least three technicians using two lots of components

Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma

Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 41 41 41
Mean 1.96 11.5 22.1 1.83 10.5 20.3
Standard Deviation 0.17 0.49 0.68 0.19 0.76 1.5
CV% 8.7 4.3 3.1 10.4 7.2 7.4

Recovery

The recovery of TNF-alpha was determined by spiking to three different levels throughout the range of the assay in various matrices.

Sample Type Average % Recovery Range %
Citrate Plasma (n=4) 95 88-105
EDTA Plasma (n=4) 99 92-111
Heparin Plasma (n=4) 93 87-103
Serum (n=4) 93 85-98

Linearity

To assess the linearity of the assay, samples were spiked with high concentrations of TNF-alpha and diluted with calibrator diluent to produce samples with values within the dynamic range of the assay.
Human TNF-alpha High Sensitivity ELISA Linearity

Data Examples

Human TNF-alpha High Sensitivity Standard Curve

Product Datasheets

Preparation and Storage

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: TNF-alpha

Tumor necrosis factor alpha (TNF-α), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, apoptosis, and immune system development. TNF-α is produced by a wide variety of immune and epithelial cell types. Human TNF-α consists of a 35 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 177 aa extracellular domain (ECD). Within the ECD, human TNF-α shares 97% aa sequence identity with rhesus and 71% - 92% with bovine, canine, cotton rat, equine, feline, mouse, porcine, and rat TNF-α. The 26 kDa type 2 transmembrane protein is assembled intracellularly to form a noncovalently linked homotrimer. Ligation of this complex induces reverse signaling that promotes lymphocyte costimulation but diminishes monocyte responsiveness.

Cleavage of membrane bound TNF-α by TACE/ADAM17 releases a 55 kDa soluble trimeric form of TNF-α. TNF-α trimers bind the ubiquitous TNF RI and the hematopoietic cell-restricted TNF RII, both of which are also expressed as homotrimers. TNF-α regulates lymphoid tissue development through control of apoptosis. It also promotes inflammatory responses by inducing the activation of vascular endothelial cells and macrophages. TNF-α is a key cytokine in the development of several inflammatory disorders. It contributes to the development of type 2 diabetes through its effects on insulin resistance and fatty acid metabolism.

Long Name:
Tumor Necrosis Factor alpha
Entrez Gene IDs:
7124 (Human); 21926 (Mouse); 24835 (Rat); 397086 (Porcine); 280943 (Bovine); 403922 (Canine); 100033834 (Equine); 493755 (Feline); 100009088 (Rabbit)
Alternate Names:
APC1 protein; Cachectin; Cachetin; DIF; TNF; TNF, monocyte-derived; tnfa; tnf-a; TNFalpha; TNF-alpha; TNF-alphacachectin; TNFATNF, macrophage-derived; TNFSF1A; TNFSF2; TNFSF2TNF superfamily, member 2; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; Tumor necrosis factor ligand superfamily member 2; tumor necrosis factor; tumor necrosis factor-alpha

Assay Procedure

Refer to the product for complete assay procedure.

Bring all reagents and samples to room temperature before use. It is recommended that all samples, standards, and controls be assayed in duplicate.
  1.   Prepare all reagents, standard dilutions, and samples as directed in the product insert.
  2.   Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.

  3. 50 µL Assay Diluent
  4.   Add 50 µL of Assay Diluent to each well.

  5. 200 µL Standard, Control, or Sample
  6.   Add 200 µL of Standard, Control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 3 hours.
  7.   Aspirate each well and wash, repeating the process 5 times for a total of 6 washes.

  8. 200 µL Conjugate
  9.   Add 200 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours.
  10.   Aspirate and wash 6 times.

  11. 50 µL Substrate Solution
  12.   Add 50 µL Substrate Solution to each well. Cover with a new plate sealer, and incubate at room temperature for 1 hour. Do not wash the plate.

  13. 50 µL Amplifier Solution
  14.   Add 50 µL Amplifier Solution to each well. Cover with a new plate sealer, and incubate at room temperature for 30 minutes.

  15. 50 µL Stop Solution
  16. Add 50 µL of Stop Solution to each well. Read at 490 nm within 30 minutes. Set wavelength correction to 650 nm or 690 nm.

Citations for Human TNF-alpha Quantikine HS ELISA

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

139 Citations: Showing 1 - 10
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  1. Longitudinal changes of cardiac troponin and inflammation reflect progressive myocyte stretch and likelihood for hypertension in a Black male cohort: The SABPA study
    Authors: E Jansen van, L Malan, R von Känel, L Lammertyn, M Cockeran, NT Malan
    Hypertens. Res., 2019;0(0):.
    Species: Human
    Sample Types: Serum
  2. Effect of TCF7L2 polymorphism on pancreatic hormones after exenatide in type 2 diabetes
    Authors: MC Ferreira, MER da Silva, RT Fukui, M do Carmo A, S Azhar, RF Dos Santos
    Diabetol Metab Syndr, 2019;11(0):10.
    Species: Human
    Sample Types: Serum
  3. Association between baseline pro-inflammatory cytokines and brain activation during social exclusion in patients with vulnerability to suicide and depressive disorder
    Authors: I Conejero, I Jaussent, A Cazals, E Thouvenot, T Mura, E Le Bars, S Guillaume, S Squalli, P Courtet, E Olié
    Psychoneuroendocrinology, 2019;99(0):236-242.
    Species: Human
    Sample Types: Serum
  4. Intracellular localization of diacylglycerols and sphingolipids influences insulin sensitivity and mitochondrial function in human skeletal muscle
    Authors: L Perreault, SA Newsom, A Strauss, A Kerege, DE Kahn, KA Harrison, JK Snell-Berg, T Nemkov, A D'Alessand, MR Jackman, PS MacLean, BC Bergman
    JCI Insight, 2018;3(3):.
    Species: Human
    Sample Types: Plasma
  5. Prolonged mechanical ventilation worsens sepsis-induced diaphragmatic dysfunction in the rat
    Authors: M Le Dinh, S Carreira, J Obert, G Gayan-Rami, B Riou, M Beuvin, T Similowski, C Coirault, A Demoule
    PLoS ONE, 2018;13(8):e0200429.
    Species: Human
    Sample Types: Plasma
  6. Effects of the Ketogenic diet in overweight divers breathing Enriched Air Nitrox
    Authors: G Bosco, A Rizzato, S Quartesan, E Camporesi, D Mangar, M Paganini, L Cenci, S Malacrida, S Mrakic-Spo, S Moretti, A Paoli
    Sci Rep, 2018;8(1):2655.
    Species: Human
    Sample Types: Plasma
  7. Contribution of bacterial pathogens to evoking serological disease markers and aggravating disease activity in rheumatoid arthritis
    Authors: K Terato, T Waritani, R Fukai, H Shionoya, H Itoh, K Katayama
    PLoS ONE, 2018;13(2):e0190588.
    Species: Human
    Sample Types: Serum
  8. Pilot study of placental tissue collection, processing, and measurement procedures for large scale assessment of placental inflammation
    Authors: LA Sjaarda, KA Ahrens, DL Kuhr, TL Holland, UR Omosigho, BT Steffen, NL Weir, HK Tollman, RM Silver, MY Tsai, EF Schisterma
    PLoS ONE, 2018;13(5):e0197039.
    Species: Human
    Sample Types: Tissue Homogenates
  9. Decreased Count and Dysfunction of Circulating EPCs in Postmenopausal Hypercholesterolemic Females via Reducing NO Production
    Authors: Y Luo, QN Yan, WZ Wu, FY Luo
    Stem Cells Int, 2018;2018(0):2543847.
    Species: Human
    Sample Types: Plasma
  10. Interleukin-10 as a predictor of major adverse cardiovascular events in a racially and ethnically diverse population: Multi-Ethnic Study of Atherosclerosis
    Authors: D Goldwater, A Karlamangl, SS Merkin, K Watson, T Seeman
    Ann Epidemiol, 2018;0(0):.
    Species: Human
    Sample Types: Serum
  11. Elevated Inflammatory Plasma Biomarkers in Patients With Fabry Disease: A Critical Link to Heart Failure With Preserved Ejection Fraction
    Authors: H Yogasundar, A Nikhanj, BN Putko, M Boutin, S Jain-Ghai, A Khan, C Auray-Blai, ML West, GY Oudit
    J Am Heart Assoc, 2018;7(21):e009098.
    Species: Human
    Sample Types: Plasma
  12. Altered temporal variance and functional connectivity of BOLD signal is associated with state anxiety during acute systemic inflammation
    Authors: F Labrenz, F Ferri, K Wrede, M Forsting, M Schedlowsk, H Engler, S Elsenbruch, S Benson, M Costantini
    Neuroimage, 2018;0(0):.
    Species: Human
    Sample Types: Plasma
  13. A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults
    Authors: LBS Hansen, HM Roager, NB Søndertoft, RJ Gøbel, M Kristensen, M Vallès-Col, S Vieira-Sil, S Ibrügger, MV Lind, RB Mærkedahl, MI Bahl, ML Madsen, J Havelund, G Falony, I Tetens, T Nielsen, KH Allin, HL Frandsen, B Hartmann, JJ Holst, MH Sparholt, J Holck, A Blennow, JM Moll, AS Meyer, C Hoppe, JH Poulsen, V Carvalho, D Sagnelli, MD Dalgaard, AF Christense, MC Lydolph, AB Ross, S Villas-Bôa, S Brix, T Sicheritz-, K Buschard, A Linneberg, JJ Rumessen, CT Ekstrøm, C Ritz, K Kristianse, HB Nielsen, H Vestergaar, NJ Færgeman, J Raes, H Frøkiær, T Hansen, L Lauritzen, R Gupta, TR Licht, O Pedersen
    Nat Commun, 2018;9(1):4630.
    Species: Human
    Sample Types: Serum
  14. Combination of Plasma Biomarkers and Clinical Data for the Detection of Myocardial Fibrosis or Aggravation of Heart Failure Symptoms in Heart Failure with Preserved Ejection Fraction Patients
    Authors: CK Wu, MM Su, YF Wu, JJ Hwang, LY Lin
    J Clin Med, 2018;7(11):.
    Species: Human
    Sample Types: Plasma
  15. Visceral fat area is a strong predictor of leukocyte cell-derived chemotaxin 2, a potential biomarker of dyslipidemia
    Authors: K Tanisawa, H Taniguchi, X Sun, T Ito, R Kawakami, S Sakamoto, M Higuchi
    PLoS ONE, 2017;12(3):e0173310.
    Species: Human
    Sample Types: Serum
  16. Ghrelin and hormonal markers under exercise training in patients with heart failure with preserved ejection fraction: results from the Ex-DHF pilot study
    Authors: TD Trippel, V Holzendorf, M Halle, G Gelbrich, K Nolte, A Duvinage, S Schwarz, T Rutscher, J Wiora, R Wachter, C Herrmann-L, HD Duengen, G Hasenfu beta, B Pieske, F Edelmann
    ESC Heart Fail, 2017;4(1):56-65.
    Species: Human
    Sample Types: Serum
  17. Repeated Excessive Exercise Attenuates the Anti-Inflammatory Effects of Exercise in Older Men
    Authors: RE Sahl, PR Andersen, K Gronbaek, TH Morville, M Rosenkilde, HK Rasmusen, SS Poulsen, C Prats, F Dela, JW Helge
    Front Physiol, 2017;8(0):407.
    Species: Human
    Sample Types: Plasma
  18. Inflammation and Arterial Stiffness in Chronic Kidney Disease: Findings From the CRIC Study
    Authors: E Peyster, J Chen, HI Feldman, AS Go, J Gupta, N Mitra, Q Pan, A Porter, M Rahman, D Raj, M Reilly, MR Wing, W Yang, RR Townsend,
    Am. J. Hypertens., 2017;30(4):400-408.
    Species: Human
    Sample Types: Plasma
  19. Immunometabolic dysregulation is associated with reduced cortical thickness of the anterior cingulate cortex
    Authors: Laura S van Velzen
    Brain Behav. Immun, 2017;60(0):361-368.
    Species: Human
    Sample Types: Plasma
  20. Chemokine signals are crucial for enhanced homing and differentiation of circulating osteoclast progenitor cells
    Authors: A Sucur, Z Jajic, M Artukovic, MI Matijasevi, B Anic, D Flegar, A Markotic, T Kelava, S Ivcevic, N Kovacic, V Katavic, D Grcevic
    Arthritis Res. Ther., 2017;19(1):142.
    Species: Human
    Sample Types: Plasma
  21. The association between three major physiological stress systems and oxidative DNA and lipid damage
    Authors: CN Black, M Bot, D Révész, PG Scheffer, B Penninx
    Psychoneuroendocrinology, 2017;80(0):56-66.
    Species: Human
    Sample Types: Plasma
  22. Sarcopenia correlates with systemic inflammation in COPD
    Authors: MK Byun, EN Cho, J Chang, CM Ahn, HJ Kim
    Int J Chron Obstruct Pulmon Dis, 2017;12(0):669-675.
    Species: Human
    Sample Types:
  23. Tryptophan Metabolism in Patients With Chronic Kidney Disease Secondary to Type 2 Diabetes: Relationship to Inflammatory Markers
    Authors: S Debnath, C Velagapudi, L Redus, F Thameem, B Kasinath, CE Hura, C Lorenzo, HE Abboud, JC O'Connor
    Int J Tryptophan Res, 2017;10(0):1178646917694.
    Species: Human
    Sample Types: Plasma
  24. Microenvironment inflammatory infiltrate drives growth speed and outcome of hepatocellular carcinoma: a prospective clinical study
    Authors: R Critelli, F Milosa, F Faillaci, R Condello, E Turola, L Marzi, B Lei, F Dituri, S Andreani, P Sighinolfi, P Manni, A Maiorana, C Caporali, F di Benedet, M Del Buono, N De Maria, F Schepis, ML Martinez-C, G Giannelli, E Villa
    Cell Death Dis, 2017;8(8):e3017.
    Species: Human
    Sample Types: Serum
  25. Partial lipodystrophy in patients who have undergone hematopoietic stem cell transplantation during childhood: an institutional cross-sectional survey
    Authors: M Adachi, Y Oto, K Muroya, J Hanakawa, Y Asakura, H Goto
    Clin Pediatr Endocrinol, 2017;26(2):99-108.
    Species: Human
    Sample Types: Serum
  26. Association of plasma CD40L with acute chest syndrome in sickle cell anemia
    Authors: VT Garrido, L Sonzogni, SN Mtatiro, FF Costa, N Conran, SL Thein
    Cytokine, 2017;97(0):104-107.
    Species: Human
    Sample Types: Plasma
  27. Heat and Hypoxic Acclimation Increase Monocyte Heat Shock Protein 72 but Do Not Attenuate Inflammation following Hypoxic Exercise
    Authors: BJ Lee, CD Thake
    Front Physiol, 2017;8(0):811.
    Species: Human
    Sample Types: Plasma
  28. Reduction of c-Fos via Overexpression of miR-34a Results in Enhancement of TNF- Production by LPS in Neutrophils from Myelodysplastic Syndrome Patients
    PLoS ONE, 2016;11(8):e0158527.
    Species: Human
    Sample Types: Cell Culture Supernates
  29. Circadian misalignment increases cardiovascular disease risk factors in humans
    Proc. Natl. Acad. Sci. U.S.A., 2016;113(10):E1402-11.
    Species: Human
    Sample Types: Serum
  30. Nitric oxide and tumour necrosis factor alpha in the process of pseudoexfoliation glaucoma
    Authors: TS Sarenac Vu, SM Pavlovic, VLj Jakovljevi, KB Janicijevi, NS Zdravkovic
    Int J Ophthalmol, 2016;9(8):1138-42.
    Species: Human
    Sample Types: Serum
  31. Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury
    J Clin Invest, 2016;0(0):.
    Species: Human
    Sample Types: Serum
  32. Trait Hostility and Acute Inflammatory Responses to Stress in the Laboratory
    Authors: Dominique Girard
    PLoS ONE, 2016;11(6):e0156329.
    Species: Human
    Sample Types: Serum
  33. Anti-TNF-? Drugs Differently Affect the TNF?-sTNFR System and Monocyte Subsets in Patients with Psoriasis
    PLoS ONE, 2016;11(12):e0167757.
  34. Interleukin-6 Is a Risk Factor for Atrial Fibrillation in Chronic Kidney Disease: Findings from the CRIC Study.
    Authors: Amdur R, Mukherjee M, Go A, Barrows I, Ramezani A, Shoji J, Reilly M, Gnanaraj J, Deo R, Roas S, Keane M, Master S, Teal V, Soliman E, Yang P, Feldman H, Kusek J, Tracy C, Raj D
    PLoS ONE, 2016;11(2):e0148189.
    Species: Human
    Sample Types: Plasma
  35. Effects of nateglinide and rosiglitazone on pancreatic alpha- and beta-cells, GLP-1 secretion and inflammatory markers in patients with type 2 diabetes: randomized crossover clinical study.
    Authors: Tostes G, Cunha M, Fukui R, Correia M, Rocha D, Dos Santos R, da Silva M
    Diabetol Metab Syndr, 2016;8(0):1.
    Species: Human
    Sample Types: Serum
  36. Association study of arcuate nucleus neuropeptide Y neuron receptor gene variation and serum NPY levels in clozapine treated patients with schizophrenia
    Authors: E Leinonen
    Eur. Psychiatry, 2016;40(0):13-19.
    Species: Human
    Sample Types: Serum
  37. Comparative analysis of three human adipocyte size measurement methods and their relevance for cardiometabolic risk
    Authors: André Tchernof
    Obesity (Silver Spring), 2016;0(0):.
    Species: Human
    Sample Types: Plasma
  38. Inflammatory and immunological profiles in patients with COPD: relationship with FEV 1 reversibility
    Authors: Cleriston Farias Queiroz
    J Bras Pneumol, 2016;42(4):241-247.
    Species: Human
    Sample Types: Serum
  39. The relationship between circulating neutrophil gelatinase-associated lipocalin and early alteration of metabolic parameters is associated with dietary saturated fat intake in non-diabetic Korean women
    Authors: GY Na, SR Yoon, J An, R Yeo, J Song, MN Jo, S Han, OY Kim
    Endocr. J, 2016;0(0):.
    Species: Human
    Sample Types: Plasma
  40. Casein glycomacropeptide for active distal ulcerative colitis: a randomised pilot study
    Authors: CL Hvas, A Dige, M Bendix, PG Wernlund, LA Christense, JF Dahlerup, J Agnholt
    Eur J Clin Invest, 2016;0(0):.
    Species: Human
    Sample Types: Plasma
  41. Tumor necrosis factor-alpha confers cardioprotection through ectopic expression of keratins K8 and K18.
    Authors: Papathanasiou S, Rickelt S, Soriano M, Schips T, Maier H, Davos C, Varela A, Kaklamanis L, Mann D, Capetanaki Y
    Nat Med, 2015;21(9):1076-84.
    Species: Human
    Sample Types: Serum
  42. A randomized, placebo controlled trial of omega-3 fatty acids in the treatment of young children with autism.
    Authors: Mankad D, Dupuis A, Smile S, Roberts W, Brian J, Lui T, Genore L, Zaghloul D, Iaboni A, Marcon P, Anagnostou E
    Mol Autism, 2015;6(0):18.
    Species: Human
    Sample Types: Plasma
  43. Plasma TNF-alpha and Soluble TNF Receptor Levels after Doxorubicin with or without Co-Administration of Mesna-A Randomized, Cross-Over Clinical Study.
    Authors: Hayslip J, Dressler E, Weiss H, Taylor T, Chambers M, Noel T, Miriyala S, Keeney J, Ren X, Sultana R, Vore M, Butterfield D, St Clair D, Moscow J
    PLoS ONE, 2015;10(4):e0124988.
    Species: Human
    Sample Types: Plasma
  44. Association between Inflammation and Cardiac Geometry in Chronic Kidney Disease: Findings from the CRIC Study.
    Authors: Gupta J, Dominic E, Fink J, Ojo A, Barrows I, Reilly M, Townsend R, Joffe M, Rosas S, Wolman M, Patel S, Keane M, Feldman H, Kusek J, Raj D
    PLoS ONE, 2015;10(4):e0124772.
    Species: Human
    Sample Types: Plasma
  45. Disturbances in Hypothalamic-Pituitary-Adrenal Axis and Immunological Activity Differentiating between Unipolar and Bipolar Depressive Episodes.
    Authors: Becking K, Spijker A, Hoencamp E, Penninx B, Schoevers R, Boschloo L
    PLoS ONE, 2015;10(7):e0133898.
    Species: Human
    Sample Types: Plasma
  46. Effects of Acute Endurance Exercise Performed in the Morning and Evening on Inflammatory Cytokine and Metabolic Hormone Responses.
    Authors: Kim H, Konishi M, Takahashi M, Tabata H, Endo N, Numao S, Lee S, Kim Y, Suzuki K, Sakamoto S
    PLoS ONE, 2015;10(9):e0137567.
    Species: Human
    Sample Types: Plasma
  47. Tumor-specific cytotoxic T lymphocyte activity determines colorectal cancer patient prognosis.
    Authors: Reissfelder C, Stamova S, Gossmann C, Braun M, Bonertz A, Walliczek U, Grimm M, Rahbari N, Koch M, Saadati M, Benner A, Buchler M, Jager D, Halama N, Khazaie K, Weitz J, Beckhove P
    J Clin Invest, 2015;125(2):739-51.
    Species: Human
    Sample Types: Tissue Homogenates
  48. Sclerostin, TNF-alpha and Interleukin-18 Correlate and are Together with Klotho Related to Other Growth Factors and Cytokines in Haemodialysis Patients.
    Authors: Almroth G, Lonn J, Uhlin F, Brudin L, Andersson B, Hahn-Zoric M
    Scand J Immunol, 2015;83(1):58-63.
    Species: Human
    Sample Types: Serum
  49. Effects of pentoxifylline on proteinuria and glucose control in patients with type 2 diabetes: a prospective randomized double-blind multicenter study.
    Authors: Han S, Kim H, Kim D, Sheen S, Chung C, Ahn C, Kim S, Cho Y, Park S, Kim S, Kim C, Kim K, Lee K
    Diabetol Metab Syndr, 2015;7(0):64.
    Species: Human
    Sample Types: Serum
  50. Association of Sarcopenic Obesity with Higher Serum High-Sensitivity C-Reactive Protein Levels in Chinese Older Males--A Community-Based Study (Taichung Community Health Study-Elderly, TCHS-E).
    Authors: Yang C, Li C, Li T, Liu C, Lin C, Lin W, Lin C
    PLoS ONE, 2015;10(7):e0132908.
    Species: Human
    Sample Types: Serum
  51. Differential Patterns and Determinants of Cardiac Autonomic Nerve Dysfunction during Endotoxemia and Oral Fat Load in Humans.
    Authors: Ziegler D, Strom A, Strassburger K, Nowotny B, Zahiragic L, Nowotny P, Carstensen-Kirberg M, Herder C, Szendroedi J, Roden M
    PLoS ONE, 2015;10(4):e0124242.
    Species: Human
    Sample Types: Serum
  52. Zinc supplementation improves anticancer activity of monocytes in type-2 diabetic patients with metabolic syndrome.
    Authors: Meksawan K, Sermsri U, Chanvorachote P
    Anticancer Res, 2014;34(1):295-9.
    Species: Human
    Sample Types: Plasma
  53. Effect of IL-6 on the insulin sensitivity in patients with type 2 diabetes.
    Authors: Harder-Lauridsen N, Krogh-Madsen R, Holst J, Plomgaard P, Leick L, Pedersen B, Fischer C
    Am J Physiol Endocrinol Metab, 2014;306(7):E769-78.
    Species: Human
    Sample Types: Plasma
  54. Smac mimetics and innate immune stimuli synergize to promote tumor death.
    Authors: Beug S, Tang V, Lacasse E, Cheung H, Beauregard C, Brun J, Nuyens J, Earl N, St-Jean M, Holbrook J, Dastidar H, Mahoney D, Ilkow C, Le Boeuf F, Bell J, Korneluk R
    Nat Biotechnol, 2014;32(2):182-90.
    Species: Human
    Sample Types: Cell Culture Supernates
  55. Compartment differences of inflammatory activity in chronic obstructive pulmonary disease.
    Authors: Ji J, von Scheele I, Bergstrom J, Billing B, Dahlen B, Lantz A, Larsson K, Palmberg L
    Respir Res, 2014;15(0):104.
    Species: Human
    Sample Types: Serum
  56. Big breakfast rich in protein and fat improves glycemic control in type 2 diabetics.
    Authors: Rabinovitz H, Boaz M, Ganz T, Jakubowicz D, Matas Z, Madar Z, Wainstein J
    Obesity (Silver Spring), 2014;22(5):E46-54.
    Species: Human
    Sample Types: Plasma
  57. Role of diacylglycerol activation of PKCtheta in lipid-induced muscle insulin resistance in humans.
    Authors: Szendroedi J, Yoshimura T, Phielix E, Koliaki C, Marcucci M, Zhang D, Jelenik T, Muller J, Herder C, Nowotny P, Shulman G, Roden M
    Proc Natl Acad Sci U S A, 2014;111(26):9597-602.
    Species: Human
    Sample Types: Plasma
  58. Circulating mitochondrial DNA increases with age and is a familiar trait: Implications for "inflamm-aging"
    Authors: Pinti M, Cevenini E, Nasi M, De Biasi S, Salvioli S, Monti D, Benatti S, Gibellini L, Cotichini R, Stazi M, Trenti T, Franceschi C, Cossarizza A
    Eur J Immunol, 2014;44(5):1552-62.
    Species: Human
    Sample Types: Plasma
  59. High-salt intake induced visceral adipose tissue hypoxia and its association with circulating monocyte subsets in humans.
    Authors: Zhou X, Yuan F, Ji W, Guo Z, Zhang L, Lu R, Liu X, Liu H, Zhang W, Jiang T, Zhang Z, Li Y
    Obesity (Silver Spring), 2014;22(6):1470-6.
    Species: Human
    Sample Types: Serum
  60. Race modifies the association between adiposity and inflammation in patients with chronic kidney disease: findings from the chronic renal insufficiency cohort study.
    Authors: Wing M, Yang W, Teal V, Navaneethan S, Tao K, Ojo A, Guzman N, Reilly M, Wolman M, Rosas S, Cuevas M, Fischer M, Lustigova E, Master S, Xie D, Appleby D, Joffe M, Kusek J, Feldman H, Raj D
    Obesity (Silver Spring), 2014;22(5):1359-66.
    Species: Human
    Sample Types: Plasma
  61. The impact of two different transfusion strategies on patient immune response during major abdominal surgery: a preliminary report.
    Authors: Theodoraki K, Markatou M, Rizos D, Fassoulaki A
    J Immunol Res, 2014;2014(0):945829.
    Species: Human
    Sample Types: Plasma
  62. The protective effect of esculentoside a on experimental acute liver injury in mice.
    Authors: Zhang F, Wang X, Qiu X, Wang J, Fang H, Wang Z, Sun Y, Xia Z
    PLoS ONE, 2014;9(11):e113107.
    Species: Human
    Sample Types: Cell Culture Supernates
  63. Threonyl-tRNA synthetase overexpression correlates with angiogenic markers and progression of human ovarian cancer.
    Authors: Wellman T, Eckenstein M, Wong C, Rincon M, Ashikaga T, Mount S, Francklyn C, Lounsbury K
    BMC Cancer, 2014;14(0):620.
    Species: Human
    Sample Types: Serum
  64. Association between traffic-related air pollution, subclinical inflammation and impaired glucose metabolism: results from the SALIA study.
    Authors: Teichert T, Vossoughi M, Vierkotter A, Sugiri D, Schikowski T, Schulte T, Roden M, Luckhaus C, Herder C, Kramer U
    PLoS ONE, 2013;8(12):e83042.
    Species: Human
    Sample Types: Plasma
  65. Exenatide as a weight-loss therapy in extreme pediatric obesity: a randomized, controlled pilot study.
    Authors: Kelly AS, Metzig AM, Rudser KD, Fitch AK, Fox CK, Nathan BM, Deering MM, Schwartz BL, Abuzzahab MJ, Gandrud LM, Moran A, Billington CJ, Schwarzenberg SJ
    Obesity (Silver Spring), 2012;20(2):364-70.
    Species: Human
    Sample Types: Plasma
  66. Multiplexing immunoassays for cytokine detection in the serum of patients with rheumatoid arthritis: lack of sensitivity and interference by rheumatoid factor.
    Authors: Churchman SM, Geiler J, Parmar R, Horner EA, Church LD, Emery P, Buch MH, McDermott MF, Ponchel F
    Clin. Exp. Rheumatol., 2012;30(4):534-42.
    Species: Human
    Sample Types: Serum
  67. Adipocytokine levels mark endothelial function in normotensive individuals.
    Authors: Solini A, Stea F, Santini E, Bruno R, Duranti E, Taddei S, Ghiadoni L
    Cardiovasc Diabetol, 2012;11(0):103.
    Species: Human
    Sample Types: Plasma
  68. A randomized trial of recombinant human granulocyte-macrophage colony stimulating factor for patients with acute lung injury.
    Authors: Paine R, Standiford TJ, Dechert RE, Moss M, Martin GS, Rosenberg AL, Thannickal VJ, Burnham EL, Brown MB, Hyzy RC
    Crit. Care Med., 2012;40(1):90-7.
    Species: Human
    Sample Types: BALF
  69. Engulfment of hematopoietic stem cells caused by down-regulation of CD47 is critical in the pathogenesis of hemophagocytic lymphohistiocytosis.
    Authors: Kuriyama T, Takenaka K, Kohno K, Yamauchi T, Daitoku S, Yoshimoto G, Kikushige Y, Kishimoto J, Abe Y, Harada N, Miyamoto T, Iwasaki H, Teshima T, Akashi K
    Blood, 2012;120(19):4058-67.
    Species: Human
    Sample Types: Serum
  70. Fractalkine is an independent predictor of mortality in patients with advanced heart failure.
    Thromb Haemost, 2012;108(6):1220-7.
    Species: Human
    Sample Types: Plasma
  71. Time-course of changes in inflammatory response after whole-body cryotherapy multi exposures following severe exercise.
    Authors: Pournot H, Bieuzen F, Louis J, Fillard JR, Barbiche E, Hausswirth C
    PLoS ONE, 2011;6(7):e22748.
    Species: Human
    Sample Types: Plasma
  72. Effects of dietary fat modification on insulin sensitivity and on other risk factors of the metabolic syndrome-LIPGENE: a European randomized dietary intervention study.
    Authors: Tierney AC, McMonagle J, Shaw DI, Gulseth HL, Helal O, Saris WH, Paniagua JA, Golabek-Leszczynska I, Defoort C, Williams CM, Karsltrom B, Vessby B, Dembinska-Kiec A, Lopez-Miranda J, Blaak EE, Drevon CA, Gibney MJ, Lovegrove JA, Roche HM
    Int J Obes (Lond), 2011;35(6):800-9.
    Species: Human
    Sample Types: Serum
  73. Divergent anti-inflammatory effects of different oil acute consumption on healthy individuals.
    Authors: Papageorgiou N, Tousoulis D, Psaltopoulou T, Giolis A, Antoniades C, Tsiamis E, Miliou A, Toutouzas K, Siasos G, Stefanadis C
    Eur J Clin Nutr, 2011;65(4):514-9.
    Species: Human
    Sample Types: Serum
  74. Mechanisms inducing low bone density in duchenne muscular dystrophy in mice and humans.
    Authors: Rufo A, Del Fattore A, Capulli M, Carvello F, De Pasquale L, Ferrari S, Pierroz D, Morandi L, De Simone M, Rucci N, Bertini E, Bianchi ML, De Benedetti F, Teti A
    J. Bone Miner. Res., 2011;26(8):1891-903.
    Species: Human
    Sample Types: Serum
  75. Sensitive plasma protein analysis by microparticle-based proximity ligation assays.
    Authors: Darmanis S, Nong RY, Hammond M, Gu J, Alderborn A, Vanelid J, Siegbahn A, Gustafsdottir S, Ericsson O, Landegren U, Kamali-Moghaddam M
    Mol. Cell Proteomics, 2010;9(2):327-35.
    Species: Human
    Sample Types: Plasma
  76. Nonalcoholic fatty liver disease as the transducer of hepatic oversecretion of very-low-density lipoprotein-apolipoprotein B-100 in obesity.
    Authors: Chan DC, Watts GF, Gan S
    Arterioscler. Thromb. Vasc. Biol., 2010;30(5):1043-50.
    Species: Human
    Sample Types: Plasma
  77. B7-h3 augments the inflammatory response and is associated with human sepsis.
    Authors: Zhang G, Wang J, Kelly J
    J. Immunol., 2010;185(6):3677-84.
    Species: Human
    Sample Types: Plasma
  78. Prehospital resuscitation with hypertonic saline-dextran modulates inflammatory, coagulation and endothelial activation marker profiles in severe traumatic brain injured patients.
    Authors: Rhind SG, Crnko NT, Baker AJ
    J Neuroinflammation, 2010;7(0):5.
    Species: Human
    Sample Types: Serum
  79. Changes in cytokine levels during acute hyperinsulinemia in offspring of type 2 diabetic subjects.
    Authors: Ruotsalainen E, Stancakova A, Vauhkonen I, Salmenniemi U, Pihlajamaki J, Punnonen K, Laakso M
    Atherosclerosis, 2010;210(2):536-41.
    Species: Human
    Sample Types: Plasma
  80. Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: links with metabolic and low-grade inflammation markers.
    Authors: Furet JP, Kong LC, Tap J, Poitou C, Basdevant A, Bouillot JL, Mariat D, Corthier G, Dore J, Henegar C, Rizkalla S, Clement K
    Diabetes, 2010;59(12):3049-57.
    Species: Human
    Sample Types: Plasma
  81. Procalcitonin as an early marker of bacterial infection in neutropenic febrile children with acute lymphoblastic leukemia.
    Authors: Hatzistilianou M, Rekliti A, Athanassiadou F, Catriu D
    Inflamm. Res., 2010;59(5):339-47.
    Species: Human
    Sample Types: Serum
  82. SIRT1 mRNA expression may be associated with energy expenditure and insulin sensitivity.
    Authors: Rutanen J, Yaluri N, Modi S, Pihlajamaki J, Vanttinen M, Itkonen P, Kainulainen S, Yamamoto H, Lagouge M, Sinclair DA, Elliott P, Westphal C, Auwerx J, Laakso M
    Diabetes, 2010;59(4):829-35.
    Species: Human
    Sample Types: Plasma
  83. Resistin, adiponectin, and risk of heart failure the Framingham offspring study.
    Authors: Frankel DS, Vasan RS, D'Agostino RB, Benjamin EJ, Levy D, Wang TJ, Meigs JB
    J. Am. Coll. Cardiol., 2009;53(9):754-62.
    Species: Human
    Sample Types: Plasma
  84. Intervention of an inflammation amplifier, triggering receptor expressed on myeloid cells 1, for treatment of autoimmune arthritis.
    Authors: Murakami Y, Akahoshi T, Aoki N, Toyomoto M, Miyasaka N, Kohsaka H
    Arthritis Rheum., 2009;60(6):1615-23.
    Species: Human
    Sample Types: Serum
  85. Urinary proinflammatory cytokine response in renal transplant recipients with polyomavirus BK viruria.
    Authors: Sadeghi M, Daniel V, Schnitzler P, Lahdou I, Naujokat C, Zeier M, Opelz G
    Transplantation, 2009;88(9):1109-16.
    Species: Human
    Sample Types: Urine
  86. Adiposity and gingival crevicular fluid tumour necrosis factor-alpha levels in children.
    Authors: Khosravi R, Tran SD, Lambert M, O'Loughlin J, Kâ K, Feine JS, Caron C, Tremblay A, Nicolau B
    J. Clin. Periodontol., 2009;36(4):301-7.
    Species: Human
    Sample Types: Gingival Crevicular Fluid (GCF)
  87. Interleukin-18 is a strong predictor of cardiovascular events in elderly men with the metabolic syndrome: synergistic effect of inflammation and hyperglycemia.
    Authors: Troseid M, Seljeflot I, Hjerkinn EM, Arnesen H
    Diabetes Care, 2009;32(3):486-92.
    Species: Human
    Sample Types: Serum
  88. Acetaldehyde stimulates monocyte adhesion in a P-selectin- and TNFalpha-dependent manner.
    Authors: Redmond EM, Morrow D, Kundimi S, Miller-Graziano CL, Cullen JP
    Atherosclerosis, 2009;204(2):372-80.
    Species: Human
    Sample Types: Cell Culture Supernates
  89. Age-dependent mobilization of circulating endothelial progenitor cells in infants and young children undergoing cardiac surgery with cardiopulmonary bypass.
    Authors: Sun Y, Yi D, Wang Y, Zheng R, Sun G, Wang J, Liu Y, Ren J, Wang Y, Zhang S, Gu C, Pei J
    Cytokine, 2009;47(3):206-13.
    Species: Human
    Sample Types: Plasma
  90. Differential effects of arsenic on cutaneous and systemic immunity: focusing on CD4+ cell apoptosis in patients with arsenic-induced Bowen's disease.
    Authors: Liao WT, Yu CL, Lan CC, Lee CH, Chang CH, Chang LW, You HL, Yu HS
    Carcinogenesis, 2009;30(6):1064-72.
    Species: Human
    Sample Types: Cell Culture Supernates
  91. Predictors of maintaining cognitive function in older adults: the Health ABC study.
    Authors: Yaffe K, Fiocco AJ, Lindquist K, Vittinghoff E, Simonsick EM, Newman AB, Satterfield S, Rosano C, Rubin SM, Ayonayon HN, Harris TB,
    Neurology, 2009;72(23):2029-35.
    Species: Human
    Sample Types: Plasma
  92. Immunomodulation by chronobiologically-based glucocorticoids treatment for multiple sclerosis relapses.
    Authors: Glass-Marmor L, Paperna T, Galboiz Y, Miller A
    J. Neuroimmunol., 2009;210(1):124-7.
    Species: Human
    Sample Types: Serum
  93. Adrenomedullin and endothelin-1 are related to inflammation in chronic heart failure.
    Authors: Gombos T, Forhecz Z, Pozsonyi Z, Wallentin S, Papassotiriou J, Kunde J, Morgenthaler NG, Janoskuti L, Prohaszka Z
    Inflamm. Res., 2009;58(6):298-305.
    Species: Human
    Sample Types: Serum
  94. Smoking, inflammatory patterns and postprandial hypertriglyceridemia.
    Authors: Kabagambe EK, Ordovas JM, Tsai MY, Borecki IB, Hopkins PN, Glasser SP, Arnett DK
    Atherosclerosis, 2009;203(2):633-9.
    Species: Human
    Sample Types: Serum
  95. Two large preoperative doses of erythropoietin do not reduce the systemic inflammatory response to cardiac surgery.
    Authors: Poulsen TD, Andersen LW, Steinbruchel D, Gotze JP, Jorgensen OS, Olsen NV
    J. Cardiothorac. Vasc. Anesth., 2009;23(3):316-23.
    Species: Human
    Sample Types: Plasma
  96. The proinflammatory environment in potential heart and lung donors: prevalence and impact of donor management and hormonal therapy.
    Authors: Venkateswaran RV, Dronavalli V, Lambert PA, Steeds RP, Wilson IC, Thompson RD, Mascaro JG, Bonser RS
    Transplantation, 2009;88(4):582-8.
    Species: Human
    Sample Types: Serum
  97. Characteristics of dengue virus-infected peripheral blood mononuclear cell death that correlates with the severity of illness.
    Authors: Jaiyen Y, Masrinoul P, Kalayanarooj S, Pulmanausahakul R, Ubol S
    Microbiol. Immunol., 2009;53(8):442-50.
    Species: Human
    Sample Types: Plasma
  98. Interleukin-6 is a significant predictor of radiographic knee osteoarthritis: The Chingford Study.
    Authors: Livshits G, Zhai G, Hart DJ, Kato BS, Wang H, Williams FM, Spector TD
    Arthritis Rheum., 2009;60(7):2037-45.
    Species: Human
    Sample Types: Serum
  99. Serum CXCL13 positively correlates with prostatic disease, prostate-specific antigen and mediates prostate cancer cell invasion, integrin clustering and cell adhesion.
    Authors: Singh S, Singh R, Sharma PK, Singh UP, Rai SN, Chung LW, Cooper CR, Novakovic KR, Grizzle WE, Lillard JW
    Cancer Lett., 2009;283(1):29-35.
    Species: Human
    Sample Types: Serum
  100. Associations of circulating TNFalpha and IL-18 with myocardial infarction and cardiovascular risk markers: the Glasgow Myocardial Infarction Study.
    Authors: Welsh P, Woodward M, Rumley A, Lowe G
    Cytokine, 2009;47(2):143-7.
    Species: Human
    Sample Types: Plasma
  101. Sex differences in inflammatory markers: what is the contribution of visceral adiposity?
    Authors: Cartier A, Cote M, Lemieux I, Perusse L, Tremblay A, Bouchard C, Despres JP
    Am. J. Clin. Nutr., 2009;89(5):1307-14.
    Species: Human
    Sample Types: Plasma
  102. Self-esteem levels and cardiovascular and inflammatory responses to acute stress.
    Authors: O'Donnell K, Brydon L, Wright CE, Steptoe A
    Brain Behav. Immun., 2008;0(0):.
    Species: Human
    Sample Types: Plasma
  103. Identification of interleukin-7 as a candidate disease mediator in spondylarthritis.
    Authors: Rihl M, Kellner H, Kellner W, Barthel C, Yu DT, Tak PP, Zeidler H, Baeten D
    Arthritis Rheum., 2008;58(11):3430-5.
    Species: Human
    Sample Types: Synovial Fluid
  104. An oil mixture with trans-10, cis-12 conjugated linoleic acid increases markers of inflammation and in vivo lipid peroxidation compared with cis-9, trans-11 conjugated linoleic acid in postmenopausal women.
    Authors: Tholstrup T, Raff M, Straarup EM, Lund P, Basu S, Bruun JM
    J. Nutr., 2008;138(8):1445-51.
    Species: Human
    Sample Types: Serum
  105. Duffy (Fy), DARC, and neutropenia among women from the United States, Europe and the Caribbean.
    Authors: Grann VR, Ziv E, Joseph CK, Neugut AI, Wei Y, Jacobson JS, Horwitz MS, Bowman N, Beckmann K, Hershman DL
    Br. J. Haematol., 2008;143(2):288-93.
    Species: Human
    Sample Types: Plasma
  106. Low-dose acetylsalicylic acid inhibits the secretion of interleukin-6 from white adipose tissue.
    Authors: Ogston NC, Karastergiou K, Hosseinzadeh-Attar MJ, Bhome R, Madani R, Stables M, Gilroy D, Flachs P, Hensler M, Kopecky J, Mohamed-Ali V
    Int J Obes (Lond), 2008;32(12):1807-15.
    Species: Human
    Sample Types: Plasma
  107. Effects of atorvastatin added to inhaled corticosteroids on lung function and sputum cell counts in atopic asthma.
    Authors: Hothersall EJ, Chaudhuri R, McSharry C, Donnelly I, Lafferty J, McMahon AD, Weir CJ, Meiklejohn J, Sattar N, McInnes I, Wood S, Thomson NC
    Thorax, 2008;63(12):1070-5.
    Species: Human
    Sample Types: Serum
  108. Neutropenia in 6 ethnic groups from the Caribbean and the U.S.
    Authors: Grann VR, Bowman N, Joseph C, Wei Y, Horwitz MS, Jacobson JS, Santella RP, Hershman DL
    Cancer, 2008;113(4):854-60.
    Species: Human
    Sample Types: Plasma
  109. Comparing Type D personality and older age as correlates of tumor necrosis factor-alpha dysregulation in chronic heart failure.
    Authors: Denollet J, Vrints CJ, Conraads VM
    Brain Behav. Immun., 2008;22(5):736-43.
    Species: Human
    Sample Types: Plasma
  110. Duffy antigen modifies the chemokine response in human endotoxemia.
    Authors: Mayr FB, Spiel AO, Leitner JM, Firbas C, Kliegel T, Jilma-Stohlawetz P, Derendorf H, Jilma B
    Crit. Care Med., 2008;36(1):159-65.
    Species: Human
    Sample Types: Plasma
  111. Flaxseed oil and fish-oil capsule consumption alters human red blood cell n-3 fatty acid composition: a multiple-dosing trial comparing 2 sources of n-3 fatty acid.
    Authors: Barcelo-Coblijn G, Murphy EJ, Othman R, Moghadasian MH, Kashour T, Friel JK
    Am. J. Clin. Nutr., 2008;88(3):801-9.
    Species: Human
    Sample Types: Plasma
  112. In vivo transmigrated monocytes from patients with stable coronary artery disease have a reduced expression of CD11b.
    Authors: Paulsson JM, Dadfar E, Held C, Jacobson SH, Lundahl J
    Clin. Exp. Immunol., 2008;153(2):196-204.
    Species: Human
    Sample Types: Serum
  113. Selective effects of CPAP on sleep apnoea-associated manifestations.
    Authors: Vgontzas AN, Zoumakis E, Bixler EO, Lin HM, Collins B, Basta M, Pejovic S, Chrousos GP
    Eur. J. Clin. Invest., 2008;38(8):585-95.
    Species: Human
    Sample Types: Plasma
  114. Decreased lubricin concentrations and markers of joint inflammation in the synovial fluid of patients with anterior cruciate ligament injury.
    Authors: Elsaid KA, Fleming BC, Oksendahl HL, Machan JT, Fadale PD, Hulstyn MJ, Shalvoy R, Jay GD
    Arthritis Rheum., 2008;58(6):1707-15.
    Species: Human
    Sample Types: Synovial Fluid
  115. Inflammatory markers and incident fracture risk in older men and women: the Health Aging and Body Composition Study.
    Authors: Cauley JA, Danielson ME, Boudreau RM, Forrest KY, Zmuda JM, Pahor M, Tylavsky FA, Cummings SR, Harris TB, Newman AB
    J. Bone Miner. Res., 2007;22(7):1088-95.
    Species: Human
    Sample Types: Serum
  116. Effects of rehabilitative exercise on peripheral muscle TNFalpha, IL-6, IGF-I and MyoD expression in patients with COPD.
    Authors: Vogiatzis I, Stratakos G, Simoes DC, Terzis G, Georgiadou O, Roussos C, Zakynthinos S
    Thorax, 2007;62(11):950-6.
    Species: Human
    Sample Types: Plasma
  117. Co-occurrence of IgA antibodies against ethanol metabolites and tissue transglutaminase in alcohol consumers: correlation with proinflammatory cytokines and markers of fibrogenesis.
    Authors: Koivisto H, Hietala J, Anttila P, Niemela O
    Dig. Dis. Sci., 2007;53(2):500-5.
    Species: Human
    Sample Types: Serum
  118. Selective functional exhaustion of hematopoietic progenitor cells in the bone marrow of patients with postinfarction heart failure.
    Authors: Kissel CK, Lehmann R, Assmus B, Aicher A, Honold J, Fischer-Rasokat U, Heeschen C, Spyridopoulos I, Dimmeler S, Zeiher AM
    J. Am. Coll. Cardiol., 2007;49(24):2341-9.
    Species: Human
    Sample Types: Serum
  119. Dysregulated monocyte iron homeostasis and erythropoietin formation in patients with anemia of chronic disease.
    Authors: Theurl I, Mattle V, Seifert M, Mariani M, Marth C, Weiss G
    Blood, 2006;107(10):4142-8.
    Species: Human
    Sample Types: Serum
  120. Serum myeloperoxidase and mortality in maintenance hemodialysis patients.
    Authors: Kalantar-Zadeh K, Brennan ML, Hazen SL
    Am. J. Kidney Dis., 2006;48(1):59-68.
    Species: Human
    Sample Types: Serum
  121. Recombinant human antithrombin inhibits thrombin formation and interleukin 6 release in human endotoxemia.
    Authors: Leitner JM, Firbas C, Mayr FB, Reiter RA, Steinlechner B, Jilma B
    Clin. Pharmacol. Ther., 2006;79(1):23-34.
    Species: Human
    Sample Types: Plasma
  122. Cerebrospinal fluid IL-6, HSP72, and TNF-alpha in exercising humans.
    Authors: Steensberg A, Dalsgaard MK, Secher NH, Pedersen BK
    Brain Behav. Immun., 2006;20(6):585-9.
    Species: Human
    Sample Types: Plasma
  123. Humoral and cellular factors responsible for coronary collateral formation.
    Authors: Sherman JA, Hall A, Malenka DJ, De Muinck ED, Simons M
    Am. J. Cardiol., 2006;98(9):1194-7.
    Species: Human
    Sample Types: Plasma
  124. Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2.
    Authors: Haukeland JW, Damas JK, Konopski Z, Loberg EM, Haaland T, Goverud I, Torjesen PA, Birkeland K, Bjoro K, Aukrust P
    J. Hepatol., 2006;44(6):1167-74.
    Species: Human
    Sample Types: Serum
  125. The activity of N-acetyl-beta-D-glucosaminidase and tumor necrosis factor-alpha at early stage of diabetic retinopathy development in type 1 diabetes mellitus children.
    Authors: Mysliwiec M, Zorena K, Balcerska A, Mysliwska J, Lipowski P, Raczynska K
    Clin. Biochem., 2006;39(8):851-6.
    Species: Human
    Sample Types: Serum
  126. Analysis of tumor necrosis factor-alpha, interleukin-6, interleukin-1beta, soluble tumor necrosis factor receptors I and II, interleukin-6 soluble receptor, interleukin-1 soluble receptor type II, interleukin-1 receptor antagonist, and protein in the synovial fluid of patients with temporomandibular joint disorders.
    Authors: Kaneyama K, Segami N, Sun W, Sato J, Fujimura K
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2005;99(3):276-84.
    Species: Human
    Sample Types: Synovial Fluid
  127. Tumor necrosis factor alpha and adiponectin in bone marrow interstitial fluid from patients with acute myeloid leukemia inhibit normal hematopoiesis.
    Authors: Iversen PO, Wiig H
    Clin. Cancer Res., 2005;11(19):6793-9.
    Species: Human
    Sample Types: Plasma
  128. Cytokines and adhesion molecules in multiple sclerosis patients treated with interferon-beta1b.
    Authors: Jensen J, Krakauer M, Sellebjerg F
    Cytokine, 2005;29(1):24-30.
    Species: Human
    Sample Types: Plasma
  129. Strong inflammatory cytokine response in male and strong anti-inflammatory response in female kidney transplant recipients with urinary tract infection.
    Authors: Sadeghi M, Daniel V, Naujokat C, Wiesel M, Hergesell O, Opelz G
    Transpl. Int., 2005;18(2):177-85.
    Species: Human
    Sample Types: Plasma
  130. Escape from cardiomyocyte apoptosis by enterovirus persistence due to elevated soluble Fas-receptors.
    Authors: Alter P, Maisch B
    Z Kardiol, 2004;93(7):524-32.
    Species: Human
    Sample Types: Serum
  131. Immunodetection of a hepatitis C virus (HCV) antigen and Thl/Th2 cytokines in cerebrospinal fluid of meningitis patients.
    Authors: Attallah AM, Ibrahim GG
    J Immunoassay Immunochem, 2004;25(4):313-20.
    Species: Human
    Sample Types: Serum
  132. Markers of inflammation in exhaled breath condensate of young healthy smokers.
    Authors: Garey KW, Neuhauser MM, Robbins RA, Danziger LH, Rubinstein I
    Chest, 2004;125(1):22-6.
    Species: Human
    Sample Types: Exhaled Breath Condensate (EBC)
  133. TGF-beta in human milk is associated with wheeze in infancy.
    Authors: Oddy WH, Halonen M, Martinez FD, Lohman IC, Stern DA, Kurzius-Spencer M, Guerra S, Wright AL
    J. Allergy Clin. Immunol., 2003;112(4):723-8.
    Species: Human
    Sample Types: Milk
  134. Evaluation of tumor necrosis factor-alpha and erythropoietin serum levels in B-cell chronic lymphocytic leukemia patients with anemia.
    Authors: Capalbo S, Battista C, Delia M, Ciancio A, De Santis G, Dargenio M, Diomede D, Liso V
    Acta Haematol., 2002;108(2):84-9.
    Species: Human
    Sample Types: Serum
  135. Impaired responsiveness to NO in newly diagnosed patients with rheumatoid arthritis.
    Authors: Bergholm R, Leirisalo-Repo M, Vehkavaara S, Makimattila S, Taskinen MR, Yki-Jarvinen H
    Arterioscler. Thromb. Vasc. Biol., 2002;22(10):1637-41.
    Species: Human
    Sample Types: Serum
  136. Positive Chlamydia pneumoniae serology is associated with elevated levels of tumor necrosis factor alpha in patients with coronary heart disease.
    Authors: Schumacher A, Seljeflot I, Lerkerod AB, Sommervoll L, Otterstad JE, Arnesen H
    Atherosclerosis, 2002;164(1):153-60.
    Species: Human
    Sample Types: Serum
  137. Impact of an exercise-induced increase in cardiac troponin I in chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy.
    Authors: Schulz O, Sigusch HH
    Am. J. Cardiol., 2002;90(5):547-50.
    Species: Human
    Sample Types: Serum
  138. Tumour necrosis factor alpha and its soluble receptors in juvenile chronic arthritis.
    Authors: Rooney M, Varsani H, Martin K, Lombard PR, Dayer JM, Woo P
    Rheumatology (Oxford), 2000;39(4):432-8.
    Species: Human
    Sample Types: Serum
  139. Postprandial total and HMW adiponectin following a high-fat meal in lean, obese and diabetic men.
    Authors: Phillips L, Peake J, Zhang X, Hickman I, Briskey D, Huang B, Simpson P, Li S, Whitehead J, Martin J, Prins J
    Eur J Clin Nutr, 0;67(4):377-84.
    Species: Human
    Sample Types: Plasma

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Human TNF-alpha Quantikine HS ELISA
By Anonymous on 01/18/2018
Sample Tested: EDTA Plasma

Human TNF-alpha Quantikine HS ELISA
By Anonymous on 08/04/2017
Sample Tested: Peripheral blood neutrophils

Due to the short experimental time, the standard TNFa duoSET ELISA did not work, however HS kit did.


Human TNF-alpha Quantikine HS ELISA
By Anonymous on 05/25/2016
Sample Tested: Human serum