Human ULBP-3 Antibody

Catalog # Availability Size / Price Qty
MAB15171
MAB15171-SP
Product Details
Citations (4)
FAQs
Supplemental Products
Reviews (1)

Human ULBP-3 Antibody Summary

Species Reactivity
Human
Specificity
Detects human ULBP-3 in direct ELISAs and Western blots. In these formats, this antibody does not cross‑react with recombinant human (rh) ULBP-1 or rhULBP-2.
Source
Monoclonal Mouse IgG2A Clone # 166514
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
BaF3 mouse pro-B cell line transfected with human ULBP-3
Accession # Q9BZM4
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Human ULBP‑3 Fc Chimera (Catalog # 1517-UL)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Availability
Size / Price
Qty
RB01
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: ULBP-3

ULBP-3 is a GPI-linked cell-surface protein that functions as a ligand for human NKG2D. ULBP-1, -2, and -3 are expressed on some tumor cells and have been implicated in immune surveillance of tumors. Unlike ULBP-1 and -2, ULBP-3 does not interact with the CMV glycoprotein UL16.

Long Name
UL16 Binding Protein-3
Entrez Gene IDs
79465 (Human)
Alternate Names
NKG2D ligand 3; RAET1N; UL16 binding protein 3; ULBP3; ULBP-3

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Citations for Human ULBP-3 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

4 Citations: Showing 1 - 4
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  1. The human cytomegalovirus protein UL147A downregulates the most prevalent MICA allele: MICA*008, to evade NK cell-mediated killing
    Authors: E Seidel, L Dassa, C Schuler, E Oiknine-Dj, DG Wolf, VTK Le-Trillin, O Mandelboim
    PloS Pathogens, 2021;17(5):e1008807.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  2. A slowly cleaved viral signal peptide acts as a protein-integral immune evasion domain
    Authors: E Seidel, L Dassa, S Kahlon, B Tirosh, A Halenius, T Seidel Mal, O Mandelboim
    Nature Communications, 2021;12(1):2061.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  3. Human Metapneumovirus Escapes NK Cell Recognition through the Downregulation of Stress-Induced Ligands for NKG2D
    Authors: M Diab, D Schmiedel, E Seidel, E Bacharach, O Mandelboim
    Viruses, 2020;12(7):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  4. Effective in vivo induction of NKG2D ligands in acute myeloid leukaemias by all-trans-retinoic acid or sodium valproate.
    Authors: Poggi A, Catellani S, Garuti A, Pierri I, Gobbi M, Zocchi MR
    Leukemia, 2009;23(4):641-8.
    Species: Human
    Sample Types: Serum
    Applications: ELISA Development

FAQs

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Isotype Controls

Mouse IgG2A Isotype Control

Reconstitution Buffers

Secondary Antibodies

Reviews for Human ULBP-3 Antibody

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Human ULBP-3 Antibody
By Marry Tahani on 11/16/2018
Application: B/N Sample Tested: Pancreatic cancer cells Species: Mouse