Mouse IL-31 Antibody

R&D Systems | Catalog # AF3028

R&D Systems

Key Product Details

Species Reactivity

Validated:

Mouse

Cited:

Mouse

Applications

Validated:

Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all IL-31 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant mouse IL-31
Thr24-Cys163
Accession # Q6EAL8

Specificity

Detects mouse IL-31 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human IL-31 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Mouse IL-31 Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Mouse IL‑31

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: IL-31

IL-31 is a 25 kDa, unique member of the short chain group of alpha -helical cytokines. It is produced by activated T cells, particularly the Th2 CD4+ phenotype. Mouse IL‑31 cDNA encodes a 163 amino acid (aa) precursor that contains a 22 aa signal sequence and a 141 aa mature region. IL-31 signals through a receptor complex composed of IL-31 receptor A and Oncostatin M receptor. Mature mouse IL‑31 shares 25% aa sequence identity with mature human IL-31 and 44% aa sequence identity with a rat IL-31-like protein.

Long Name

Interleukin 31

Alternate Names

IL31

Entrez Gene IDs

386653 (Human); 76399 (Mouse)

Gene Symbol

IL31

UniProt

Q6EAL8

Additional IL-31 Products

Product Documents for Mouse IL-31 Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Mouse IL-31 Antibody

For research use only

Related Research Areas

IL-6 Family

Citations for Mouse IL-31 Antibody

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FAQs

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Associated Pathways

Th2 Differentiation Pathway
Th2 Differentiation Pathway Thumbnail