Mouse MFRP Antibody
Mouse MFRP Antibody Summary
Accession # Q8K480
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
MFRP is a type II transmembrane protein that is related to a small family of soluble frizzled-related proteins. It is the product of a dicistronic mRNA transcript that codes for two proteins; MFRP and C1qTNF5. Mouse MFRP is 584 amino acids (aa) in length. Its extracellular domain (ECD) of 494 aa contains two CUB and two LDLR class A segments, plus one frizzled domain. At least two splice variants are known in mouse. In isoform 2, amino acid residues 425‑431 of isoform 1 is substituted with Lys. Mouse MFRP ECD shares 72% aa identity with human MFRP ECD. In mouse retinal degeneration 6, MFRP is mutated.
Citations for Mouse MFRP Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 2
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ADIPOR1 is essential for vision and its RPE expression is lost in the Mfrprd6 mouse
Authors: VM Sluch, A Banks, H Li, MA Crowley, V Davis, C Xiang, J Yang, JT Demirs, J Vrouvliani, B Leehy, S Hanks, AM Hyman, J Aranda, B Chang, CE Bigelow, DS Rice
Sci Rep, 2018-09-25;8(1):14339.
Sample Types: Whole Tissue
Spatial and temporal expression of MFRP and its interaction with CTRP5.
Authors: Mandal MN, Vasireddy V, Jablonski MM
Invest. Ophthalmol. Vis. Sci., 2006-12-01;47(12):5514-21.
Sample Types: Tissue Homogenates, Whole Tissue
Applications: Electron Microscopy, IHC-Fr, Western Blot
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