Mouse S100A13 Antibody

Catalog # Availability Size / Price Qty
S100A13 in Mouse Embryo.
1 Image
Product Details
Supplemental Products

Mouse S100A13 Antibody Summary

Species Reactivity
Detects mouse S100A13 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 40% cross-reactivity with recombinant human (rh) S100A13 is observed, and less than 1% cross-reactivity with rhS100A1 and rhS100A11 is observed.
Polyclonal Goat IgG
Antigen Affinity-purified
E. coli-derived recombinant mouse S100A13
Accession # P97352
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
Western Blot
0.1 µg/mL
Recombinant Mouse S100A13 (Catalog # 4328-SA)
5-15 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunohistochemistry S100A13 antibody in Mouse Embryo by Immunohistochemistry (IHC-Fr). View Larger

S100A13 in Mouse Embryo. S100A13 was detected in immersion fixed frozen sections of mouse embryo using 15 µg/mL Goat Anti-Mouse S100A13 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4328) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Preparation and Storage

Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: S100A13

S100A13 is an 11 kDa member of the S100 (soluble in 100% saturated ammonium sulfate) family of vertebrate EF-hand Ca++-binding proteins (1-3). It is widely expressed as a homodimer with 98 amino acid (aa) long subunits (2, 3). Mouse S100A13 shares 87%, 83%, 91%, 86%, 81%, and 53% aa identity with rat, human, bovine, canine, opossum, and chicken S100A13, respectively. Like other S100 proteins, S100A13 is small and generally acidic, but it contains a basic residue-rich sequence at the C-terminus, and two EF hand motifs that bind Ca++ with differing affinities (2-4). Some S100 proteins, including S100A13, are able to bind the cell surface receptor for advanced glycation end-products (RAGE) (5). Despite lacking a signal sequence, S100A13 plays an important role in Cu++-dependent export of FGF-1 (FGF acidic) and IL-1 alpha from the cell in response to stresses such as heat shock, anoxia, and starvation (6-8). Binding of copper is necessary for formation of a multi-protein complex between S100A13, FGF-1 and p40 synaptotagmin-1 (syt-1) (9, 10). Cu++ ions supplied by S100A13 are thought to oxidize and downregulate the activity of FGF-1 prior to export (10). Calcium influx may also play a similar role in FGF-1 release from neuronal cells (11). S100A13 is composed of four amphiphilic helices that may interact with acidic phospholipid headgroups. With FGF-1 and syt-1, S100A13 likely perturbs the membrane, which allows the S100A13 protein complex to exit the cell (4, 12). S100A13 has been proposed as a marker for angiogenesis in tumors and endometrium, due to its role in stress-induced export of FGF‑1 (13, 14). Based on in house studies, S100A13 has also been found to promote neurite outgrowth from rat cortical embryonic neurons (15).

  1. Santamaria-Kisiel, L. et al. (2006) Biochem. J. 396:201. 
  2. Wicki, R. et al. (1996) Biochem. Biophys. Res. Commun. 227:594. 
  3. Ridinger, K. et al. (2000) J. Biol. Chem. 275:8686. 
  4. Li, M. et al. (2007) Biochem. Biophys. Res. Commun. 356:616. 
  5. Hsieh, H-L. et al. (2004) Biochem. Biophys. Res. Commun. 316:949. 
  6. Landriscina, M. et al. (2001) J. Biol. Chem. 276:22544. 
  7. Sivaraja, V. et al. (2006) Biophys. J. 91:1832.
  8. Mandinova, A. et al. (2003) J. Cell Sci. 116:2687.
  9. Prudovsky, I. et al. (2002) J. Cell Biol. 158:201.
  10. Landriscina, M. et al. (2001) J. Biol. Chem. 276:25549.
  11. Matsunaga, H. and H. Ueda (2006) Cell. Mol. Neurobiol. 26:237.
  12. Graziani, I. et al. (2006) Biochem. Biophys. Res. Commun. 349:192.
  13. Landriscina, M. et al. (2006) J. Neurooncol. 80:251.
  14. Hayrabedyan, S. et al. (2005) Reprod. Biol. 5:51.
  15. R&D Sytems (2007) In-house data.
Long Name
S100 Calcium Binding Protein
Entrez Gene IDs
6284 (Human); 20196 (Mouse); 295213 (Rat)
Alternate Names
S100 calcium binding protein A13; S100 calcium-binding protein A13protein S100-A13; S100A13

Product Datasheets

You must select a language.



No product specific FAQs exist for this product, however you may

View all Antibody FAQs

Isotype Controls

Reconstitution Buffers

Secondary Antibodies

Goat IgG (H+L) Antibody


Reviews for Mouse S100A13 Antibody

There are currently no reviews for this product. Be the first to review Mouse S100A13 Antibody and earn rewards!

Have you used Mouse S100A13 Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review