Mouse Serpin A6 Antibody
Mouse Serpin A6 Antibody Summary
Accession # Q06770
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Serpin A6 in Mouse Liver. Serpin A6 was detected in perfusion fixed frozen sections of mouse liver using Goat Anti-Mouse Serpin A6 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4065) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific labeling was localized to the cytoplasm of hepatocytes. View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Serpin A6
Serpin A6 (also known as corticosteroid-binding globulin/CBG and Transcortin) is a 50‑60 kDa, secreted glycoprotein member of the serpin family of protease inhibitors. It is produced by hepatocytes and transports > 90% of circulating cortisol. Although Serpin A6 is a serpin family member, it shows no protease inhibition. Mature mouse Serpin A6 is 375 amino acids (aa) in length. Over aa 23‑397, mouse Serpin A6 shares 78% and 57% aa sequence identity with rat and human Serpin A6, respectively.
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