Porcine IFN-alpha Antibody

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Product Details
Citations (8)
Supplemental Products

Porcine IFN-alpha Antibody Summary

Species Reactivity
Neutralizes pig interferon alpha
Monoclonal Mouse IgG1 Clone # K9
Protein A or G purified from hybridoma culture supernatant
Porcine IFN-alpha
Supplied as a liquid
Endotoxin Level
<1.0 EU per 1 μg of the antibody by the LAL method.


Recommended Concentration

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
After receipt, this product should be kept at -20°C for retention of full activity. Do not store below -20°C.

Background: IFN-alpha

Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.

  1. L'Haridon, R.M. et al. 1991, Hybridoma 10:35-47.
  2. Splichal, I. et al. 1994, Immunology Letters 43:203-208.
Long Name
Interferon alpha
Entrez Gene IDs
3440 (Human)
Alternate Names
IFNA; IFNA2; IFNA2b; IFNalpha; IFN-alpha; IFN-alphaA; INFA2; interferon alpha 2; LeIF D

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Citations for Porcine IFN-alpha Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

8 Citations: Showing 1 - 8
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  1. Comparative Sequence Analysis of Historic and Current Porcine Rotavirus C Strains and Their Pathogenesis in 3-Day-Old and 3-Week-Old Piglets
    Authors: J Chepngeno, S Takanashi, A Diaz, H Michael, FC Paim, MC Rahe, JR Hayes, C Baker, D Marthaler, LJ Saif, AN Vlasova
    Front Microbiol, 2020-04-24;11(0):780.
    Species: Porcine
    Sample Types: Serum
    Applications: ELISA Capture
  2. Cytokine protein expression levels in tracheobronchial lymph node homogenates of pigs infected with pseudorabies virus.
    Authors: Miller LC, Zanella EL, Waters WR
    Clin. Vaccine Immunol., 2010-03-10;17(5):728-34.
    Species: Porcine
    Sample Types: Tissue Homogenates
    Applications: ELISA Development
  3. Toll-like receptor 7 and MyD88 knockdown by lentivirus-mediated RNA interference to porcine dendritic cell subsets.
    Authors: Alves MP, Neuhaus V, Guzylack-Piriou L, Ruggli N, McCullough KC, Summerfield A
    Gene Ther., 2007-03-01;14(10):836-44.
    Species: Porcine
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development
  4. The leader proteinase of foot-and-mouth disease virus inhibits the induction of beta interferon mRNA and blocks the host innate immune response.
    Authors: de Los Santos T, de Avila Botton S, Weiblen R, Grubman MJ
    J. Virol., 2006-02-01;80(4):1906-14.
    Species: Porcine
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development
  5. Fc gamma RII-dependent sensitisation of natural interferon-producing cells for viral infection and interferon-alpha responses.
    Authors: Balmelli C, Vincent IE, Rau H, Guzylack-Piriou L, McCullough K, Summerfield A
    Eur. J. Immunol., 2005-08-01;35(8):2406-15.
    Species: Porcine
    Sample Types: Serum
    Applications: ELISA Development
  6. Porcine reproductive and respiratory syndrome virus field isolates differ in in vitro interferon phenotypes.
    Authors: Lee SM, Schommer SK, Kleiboeker SB
    Vet. Immunol. Immunopathol., 2004-12-08;102(3):217-31.
    Species: Porcine
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development
  7. Classical swine fever virus induces proinflammatory cytokines and tissue factor expression and inhibits apoptosis and interferon synthesis during the establishment of long-term infection of porcine vascular endothelial cells.
    Authors: Bensaude E, Turner JL, Wakeley PR, Sweetman DA, Pardieu C, Drew TW, Wileman T, Powell PP
    J. Gen. Virol., 2004-04-01;85(0):1029-37.
    Species: Porcine
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development
  8. Immediate protection of swine from foot-and-mouth disease: a combination of adenoviruses expressing interferon alpha and a foot-and-mouth disease virus subunit vaccine.
    Authors: Moraes MP, Chinsangaram J, Brum MC, Grubman MJ
    Vaccine, 2003-12-12;22(2):268-79.
    Species: Porcine
    Sample Types: Plasma
    Applications: ELISA Development


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