Astrocytes are the most prevalent glial cell in the CNS. Their main role is to provide neurotrophic support and maintain CNS homeostasis; however, they are also involved in many neural functions and affect multiple complex behaviors.
Microglia, the primary immune cells of the CNS, induce neuroinflammation. Activated microglia acquire different phenotypes and have different roles in neuroinflammation. On the other hand, steady-state microglia are believed to be critical for CNS development and homeostasis.
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Microglia Activation State Markers
Microglia Steady-State Markers
Neurons, the fundamental unit of the nervous systems, are responsible for receiving internal and external sensory input, and implementing our complex bodily functions and behaviors. They can be classified a multiple of ways including by structure, function, connection, electrical properties, and neurotransmitter expression.
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Cholinergic Neuronal Markers
Dopaminergic Neuronal Markers
GABAergic Neuronal Markers
Glutamatergic Neuronal Markers
Glycinergic Neuronal Markers
Neurons - General Markers
Neurons – Structural Markers
Serotonergic Neuronal Markers
Oligodendrocytes are the glial cells responsible for myelinating axons in the CNS. They arise from precursor cells that undergo a progression of complex stages of proliferation, migration, differentiation, and maturation to produce the myelin sheath.
Oligodendrocytes - Maturation Stage Markers