13 results for "Cav1.2 Small Molecules and Peptides" in Products

Cav1.2 Small Molecules and Peptides

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on an ionic species, such as sodium or ...

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CaV1.x blocker

Chemical Name: 1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester
Purity: ≥98%
CaV1.x blocker
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CaV1.x blocker

Chemical Name: (2S-cis)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride
Purity: ≥98%
CaV1.x blocker
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CaV1.x blocker

Chemical Name: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methyloxyethyl 1-methylethyl ester
Purity: ≥98%
CaV1.x blocker
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Highly selective D4 antagonist

Chemical Name: 5-(4-Chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazole hydrochloride
Purity: ≥98%
Highly selective D4 antagonist
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CaV1.x blocker

Alternate Names: PN 200-110
Chemical Name: 4-(2,1,3-Benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylic acid methyl 1-methylethyl ester
Purity: ≥98%
CaV1.x blocker
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Potent and selective NK1 antagonist

Chemical Name: (2S,3S)-N-(2-Methoxyphenyl)methyl-2-diphenylmethyl-1-azabicyclo[2.2.2]octan-3-amine
Purity: ≥98%
Potent and selective NK1 antagonist
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Blocks IKr, hERG and L-type Ca2+ channels; class III antiarrhythmic

Chemical Name: (±)-N-[4-[4-(Ethylheptylamino)-1-hydroxybutyl]phenyl]methanesulfonamide hemifumarate
Purity: ≥98%
Blocks IKr, hERG and L-type Ca2+ channels; class III antiarrhythmic
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Non-selective Ca2+ channel blocker; also NCX inhibitor

Chemical Name: N-Benzyl-N-(3-isobutoxy-2-pyrrolidin-1-yl-propyl)aniline hydrochloride
Purity: ≥98%
Non-selective Ca2+ channel blocker; also NCX inhibitor
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CaV1.x blocker

Chemical Name: α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)benzeneacetonitrile hydrochloride
Purity: ≥98%
Pluripotent stem cell-derived cardiomyocytes secrete Pro-BNP in response to small molecule-induction of cardiac hypertrophy.
(3)
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Potent CaV1.x activator

Chemical Name: 2,5-Dimethyl-4-[2-(phenylmethyl)benzoyl]-1H-pyrrole-3-carboxylic acid methyl ester
Purity: ≥97%
Potent CaV1.x activator
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CaV1.x blocker

Alternate Names: Norvasc
Chemical Name: 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzenesulfonate
Purity: ≥98%
CaV1.x blocker
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Cognitive enhancer

Alternate Names: DM 9384
Chemical Name: N-(2,6-Dimethylphenyl)-2-oxo-1-pyrrolidineacetamide
Purity: ≥99%
Cognitive enhancer
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Cytochrome P450 inhibitor; antifungal

Alternate Names: CLT
Chemical Name: 1-(2-Chloro-α,α-diphenylbenzyl)imidazole
Purity: ≥98%
Cytochrome P450 inhibitor; antifungal
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