gamma-Secretase: Products

Many membrane proteins also occur as in soluble forms due to proteolytic cleavage by secretases. alpha-, beta-, and gamma-secretases are best known for their cleavage of APP, the protein precursor of amyloid beta peptide (A beta), a major component of Alzheimer's disease plaques.

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PF 3084014 hydrobromide 

Potent γ-secretase inhibitor
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