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gamma-Secretase: Products

Many membrane proteins also occur as in soluble forms due to proteolytic cleavage by secretases. alpha-, beta-, and gamma-secretases are best known for their cleavage of APP, the protein precursor of amyloid beta peptide (A beta), a major component of Alzheimer's disease plaques.

"gamma-Secretase" has 11 results in Products.
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DAPT 

γ-secretase inhibitor; induces neuronal differentiation; blocks Notch signaling

Compound E 

γ-secretase inhibitor; induces neuronal differentiation

DAPT 

DAPT synthesized to Ancillary Material Grade

DBZ 

γ-secretase inhibitor; inhibits Notch pathway

L-685,458 

Potent and selective γ-secretase inhibitor

BMS 299897 

Potent γ-secretase inhibitor

MRK 560 

γ-secretase inhibitor; attenuates amyloid plaque deposition

PF 3084014 hydrobromide 

Potent γ-secretase inhibitor

Avagacestat 

Highly potent γ-secretase inhibitor; orally bioavailable

LY 450139 

γ-secretase pseudo-inhibitor

DBZ 

DBZ synthesized to Ancillary Material Grade
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