p38 gamma: Products

The p38 Mitogen-activated Protein Kinases (MAPKs) are a family of four related Ser/Thr kinases activated by proinflammatory cytokines and environmental stresses.

The most frequently analyzed family member, p38 alpha, also known as SAPK2a and MAPK14, was initially purified as a kinase critical to the signaling cascade linking IL-1 to MAPKAPK-2 and the small heat shock protein HSP27. Ubiquitously expressed, p38 alpha is dually phosphorylated by MKK3 and MKK6 at Thr180 and Tyr182. Once activated, p38 alpha phosphorylates a number of targets, including the cytoplasmic kinases MNK 4 and PRAK5 and the nuclear transcription factors ATF2 1 and STAT1. Several promising compounds that inhibit p38 alpha are being investigated as potential therapies for arthritic and inflammatory diseases.

"p38 gamma" has 7 results in Products.
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Human/Mouse/Rat p38 gamma Antibody

4 Images
ICC/IF, IHC, Simple Western, WB

Human/Mouse/Rat p38 gamma Antibody

3 Images
ICC/IF, Simple Western, WB

Proteome Profiler Human Phospho-MAPK Array Kit

Contains 4 membranes - each spotted in duplicate with 26 different MAPK antibodies

ML 3403

p38 inhibitor

SB 706504

p38 MAPK inhibitor

DBM 1285 dihydrochloride

p38 MAPK inhibitor; anti-inflammatory
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