HIV-1 Gag p24 Antibody
HIV-1 Gag p24 Antibody Summary
Pro149-Gly354
Accession # NP_057850
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of HIV-1 Gag p24 by Western Blot. Western blot shows recombinant HIV Gag p24 (5 ng/lane). PVDF membrane was probed with 2 µg/mL of Mouse Anti-Viral HIV-1 Gag p24 Monoclonal Antibody (Catalog # MAB7360) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for HIV-1 Gag p24 at approximately 23 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: HIV-1 Gag p24
The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins which are required for virus particle assembly. p24 is a major viral core structural protein. Its measurement is commonly used as an indicator of HIV-1 infection and viral load.
Product Datasheets
Citations for HIV-1 Gag p24 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 3
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Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential
Authors: B Meyer, J Chiaravall, S Gellenonco, P Brownridge, DP Bryne, LA Daly, A Grauslys, M Walter, F Agou, LA Chakrabart, CS Craik, CE Eyers, PA Eyers, Y Gambin, AR Jones, E Sierecki, E Verdin, M Vignuzzi, E Emmott
Nature Communications, 2021-09-21;12(1):5553.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Mechanisms of HIV-1 evasion to the antiviral activity of chemokine CXCL12 indicate potential links with pathogenesis
Authors: M Armani-Tou, Z Zhou, R Gasser, I Staropoli, V Cantaloube, Y Benureau, J Garcia-Per, M Pérez-Olme, V Lorin, B Puissant-L, L Assoumou, C Delaugerre, JD Lelièvre, Y Lévy, H Mouquet, G Martin-Blo, J Alcami, F Arenzana-S, J Izopet, P Colin, B Lagane
PloS Pathogens, 2021-04-19;17(4):e1009526.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Hydroxyproline-containing collagen peptide derived from the skin of the Alaska pollack inhibits HIV-1 infection
Mol Med Rep, 2016-11-16;14(6):5489-5494.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot
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Reviews for HIV-1 Gag p24 Antibody
Average Rating: 4.5 (Based on 2 Reviews)
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gag protein w/o HIV protease, expressed in HEK293 cells, 1/500 dilution
