Human ADAM15 Ectodomain Antibody Summary
Accession # Q13444
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
ADAM15 in Human Prostate. ADAM15 was detected in immersion fixed paraffin-embedded sections of human prostate using Goat Anti-Human ADAM15 Ectodomain Antigen Affinity-purified Polyclonal Antibody (Catalog # AF935) at 5 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm in epithelial cells. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
ADAM15 belongs to a family of transmembrane proteins that contain disintegrin and metalloprotease domains. Members of this family have been implicated in cell adhesion via integrin binding and shedding of cell surface molecules.
Citations for Human ADAM15 Ectodomain Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 2
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Alternative splicing of ADAM15 regulates its interactions with cellular SH3 proteins.
Authors: Kleino I, Ortiz RM, Yritys M, Huovila AP, Saksela K
J. Cell. Biochem., 2009;108(4):877-85.
Sample Types: Cell Lysates
ADAM15 upregulation and interaction with multiple binding partners in inflammatory bowel disease.
Authors: Mosnier JF, Jarry A, Bou-Hanna C, Denis MG, Merlin D, Laboisse CL
Lab. Invest., 2006;86(10):1064-73.
Sample Types: Tissue Homogenates
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