Human BMP-2/BMP-4 Antibody

Catalog # Availability Size / Price Qty
MAB355-SP
MAB355-100
MAB355-500
Product Details
Citations (2)
FAQs
Supplemental Products
Reviews (2)

Human BMP-2/BMP-4 Antibody Summary

Species Reactivity
Human
Specificity
Detects human BMP-2 and human BMP-4 in direct ELISAs and Western blots. In direct ELISAs, this antibody shows no cross‑reactivity with recombinant human (rh) BMP-5 or rhBMP-6.
Source
Monoclonal Mouse IgG2B Clone # 65529
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
E. coli-derived recombinant human BMP-2
Ala284-Arg396
Accession # P12643
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Human BMP‑2 (Catalog # 355-BM)
Recombinant Human BMP‑4 (Catalog # 314-BP)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Availability
Size / Price
Qty
RB01
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: BMP-2/BMP-4

BMP-2 and BMP-4 belong to a family of at least 15 structurally and functionally related BMPs, which are members of the transforming growth factor beta (TGF-beta ) superfamily, BMPs were originally identified as protein regulators of cartilage and bone formation. However, they have since been shown to be involved in embryogenesis and morphogenesis of various tissues and organs.

Long Name
Bone Morphogenetic Protein 2/4
Entrez Gene IDs
650 (Human); 12156 (Mouse); 29373 (Rat)
Alternate Names
BDA2; BMP-2; BMP-2/BMP-4; BMP2A; BMP-2A; BMP2ABone morphogenetic protein 2A; bone morphogenetic protein 2

Product Datasheets

Citations for Human BMP-2/BMP-4 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. Altered bone morphogenetic protein signalling in the Helicobacter pylori-infected stomach.
    Authors: Bleuming SA, Kodach LL, Garcia Leon MJ, Richel DJ, Peppelenbosch MP, Reitsma PH, Hardwick JC, van den Brink GR
    J. Pathol., 2006;209(2):190-7.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  2. Sonic hedgehog regulates gastric gland morphogenesis in man and mouse.
    Authors: van den Brink GR, Hardwick JC, Tytgat GN, Brink MA, Ten Kate FJ, Van Deventer SJ, Peppelenbosch MP
    Gastroenterology, 2001;121(2):317-28.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P

FAQs

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Isotype Controls

Reconstitution Buffers

Secondary Antibodies

Reviews for Human BMP-2/BMP-4 Antibody

Average Rating: 5 (Based on 2 Reviews)

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Human BMP-2/BMP-4 Antibody
By Anonymous on 01/18/2022
Application: Western Blot Sample Tested: Mesenchymal stem cells Species: Human

Human BMP-2/BMP-4 Antibody
By Anonymous on 05/22/2018
Application: Immunohistochemistry Sample Tested: Tonsil tissue Species: Human