Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 494402
View all CD39L2/ENTPD6 Primary Antibodies »

Product Specifications

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human CD39L2/ENTPD6
Lys61-Ser484
Accession # O75354

Specificity

Detects human CD39L2/ENTPD6 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) CD39, rhCD39L3, or recombinant mouse CD39 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Human CD39L2/ENTPD6 Antibody

Application
Recommended Usage

Immunoprecipitation

25 µg/mL
Sample: Conditioned cell culture medium spiked with Recombinant Human CD39L2/ENTPD6 (Catalog # 4399-EN), see our available Western blot detection antibodies

Western Blot

1 µg/mL
Sample: Recombinant Human CD39L2/ENTPD6 (Catalog # 4399-EN)

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: CD39L2/ENTPD6

ENTPD6 (ectonucleoside triphosphate diphosphohydrolase-6), also known as CD39L2, is a secreted nucleoside phosphohydrolase, which catalyzes the hydrolysis of extracellular nucleotides, such as nucleoside 5'-diphosphates and nucleoside 5'-triphosphates (1). Human ENTPD6 displays a preference for the nucleoside-5’-diphosphates GDP and IDP over CDP and UDP (2). It has a broad tissue distribution, with major expression in the heart. The amino acid sequence of human CD39L2 shares 99%, 88% and 87% identity with that of chimpanzee, mouse and dog, respectively.

References

  1. Chadwick, B.P. and A.M. Frischauf (1998) Genomics. 50:357.
  2. Hicks-Berger, C.A. et al. (2000) J. Biol. Chem. 275:34041.

Long Name

Ecto-Nucleoside Triphosphate Diphosphohydrolase 6

Alternate Names

CD39L2, ENTPD6, NTPD3, NTPDase 6

Entrez Gene IDs

955 (Human); 12497 (Mouse); 85260 (Rat)

Gene Symbol

ENTPD6

UniProt

O75354

Additional CD39L2/ENTPD6 Products

Product Documents for Human CD39L2/ENTPD6 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human CD39L2/ENTPD6 Antibody

For research use only

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