Complement Component 1, r subcomponent-like protein (C1rLP) is a serine protease that is mainly expressed in the liver and has structural similarity to C1r, a component of the classical complement activation pathway. C1rLP activates pro-C1s and pro-haptoglobin. The amino acid sequence of human C1rLP is 99% and 75% identical to that of chimpanzee and dog/mouse/rat, respectively.
Human Complement Component C1rLP Antibody
R&D Systems | Catalog # MAB3676
Key Product Details
Species Reactivity
Human
Applications
Western Blot, Immunoprecipitation
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2B Clone # 393608
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Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Complement Component C1rLP
Ser41-Asn487
Accession # AAI56781
Ser41-Asn487
Accession # AAI56781
Specificity
Detects human Complement Component C1rLP in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) C1r, rhC1s, rhHaptoglobin, or rhMASP3 is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Applications for Human Complement Component C1rLP Antibody
Application
Recommended Usage
Immunoprecipitation
25 µg/mL
Sample: Conditioned cell culture medium spiked with Recombinant Human Complement Component C1rLP, see our available Western blot detection antibodies
Sample: Conditioned cell culture medium spiked with Recombinant Human Complement Component C1rLP, see our available Western blot detection antibodies
Western Blot
1 µg/mL
Sample: Recombinant Human Complement Component C1rLP
Sample: Recombinant Human Complement Component C1rLP
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
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Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Calculators
Background: Complement Component C1rLP
Long Name
Complement C1r Subcomponent-like Protein
Alternate Names
C1RL, C1RL1, CLSPa
Gene Symbol
C1RL
UniProt
Additional Complement Component C1rLP Products
Product Documents for Human Complement Component C1rLP Antibody
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human Complement Component C1rLP Antibody
For research use only
Related Research Areas
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Cellular Response to Hypoxia Protocols
- Immunoprecipitation Protocol
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars