Human Complement Factor H-related 1/CFHR1 Antibody

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Product Details
Citations (2)
Supplemental Products

Human Complement Factor H-related 1/CFHR1 Antibody Summary

Species Reactivity
Detects human Complement Factor H-related 1/CFHR1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with recombinant human (rh) CFHR2 or rhCFHR5 is observed.
Monoclonal Mouse IgG2B Clone # 442127
Protein A or G purified from hybridoma culture supernatant
Mouse myeloma cell line NS0-derived recombinant human Complement Factor H-related 1/CFHR1
Accession # Q03591
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
Western Blot
1 µg/mL
Recombinant Human Complement Factor H-related 1/CFHR1 under non-reducing conditions
25 µg/mL
Conditioned cell culture medium spiked with Recombinant Human Complement Factor H‑related 1/CFHR1, see our available Western blot detection antibodies

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Reconstitute at 0.5 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Complement Factor H-related 1/CFHR1

Complement factor H-related protein 1 (CFHR1) is a 43 kDa, secreted member of the factor H family of glycoproteins. It is produced by hepatocytes and circulates as two differentially glycosylated isoforms (37 kDa and 43 kDa). Mature human CFHR1 is 312 aa in length. It contains five approximately 60 aa SCRs (short consensus repeats/CCPs/SUSHI repeats) that basically constitute the entire molecule. CFHR1 may play a role in lipoprotein complexes that bind LPS to neutrophils. There is no reported rodent counterpart to CFHR1. Over aa 19‑143 of the CFHR1 precursor, human CFHR2 and CFHR5 show 98% and 86% aa identity, respectively.

Entrez Gene IDs
3078 (Human)
Alternate Names
BTA; CFHL1FHR-1; CFHLCFHR1P; CFHR1; complement factor H-related 1 pseudogene; Complement Factor Hrelated 1; Complement Factor H-related 1; complement factor H-related protein 1; FHR1; FHR1CFHL1P; H factor (complement)-like 1; H factor (complement)-like 2; H factor-like protein 1; H36-1; H36-2; H-factor-like 1; HFL1H36; HFL2; MGC104329

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Citations for Human Complement Factor H-related 1/CFHR1 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. Complement regulatory proteins CFHR1 and CFHR3 and patient response to anti-CD20 monoclonal antibody therapy
    Clin Cancer Res, 2016;0(0):.
    Species: Human
    Sample Types: Serum
    Applications: Western Blot
  2. A novel quantitative hemolytic assay coupled with restriction fragment length polymorphisms analysis enabled early diagnosis of atypical hemolytic uremic syndrome and identified unique predisposing mutations in Japan.
    Authors: Yoshida Y, Miyata T, Matsumoto M, Shirotani-Ikejima H, Uchida Y, Ohyama Y, Kokubo T, Fujimura Y
    PLoS ONE, 2015;10(5):e0124655.
    Species: Human
    Sample Types: Serum
    Applications: Western Blot


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