Human FAM3B Antibody
Human FAM3B Antibody Summary
Accession # NP_478066
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
FAM3B, also known as Pancreatic-derived factor (PANDER), is a secreted 23 kDa glycoprotein that belongs to the cytokine like-protein family. Members of this family share a four-helix bundle secondary structure similar to that found in many cytokines. As a result of alternative splicing and alternate signal peptide cleavage sites, multiple isoforms are known. FAM3B is expressed by pancreatic islet alpha and beta -cells, reproductive epithelium and a subset of neurons. Recombinant FAM3B has been shown to induce beta -cell apoptosis. The amino acid sequence of mature human FAM3B is 80% identical to that of mature mouse FAM3B.
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