Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 365505
View all FAM3B Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human FAM3B isoform B
Glu30-Ser235
Accession # NP_478066

Specificity

Detects human FAM3B in direct ELISAs and Western blots. In direct ELISAs and Western blots, 75‑100% cross-reactivity with recombinant mouse FAM3B and no cross-reactivity with recombinant human (rh) FAM3A, rhFAM3C, or rhFAM3D is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Human FAM3B Antibody

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Human FAM3B

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: FAM3B

FAM3B, also known as Pancreatic-derived factor (PANDER), is a secreted 23 kDa glycoprotein that belongs to the cytokine like-protein family. Members of this family share a four-helix bundle secondary structure similar to that found in many cytokines. As a result of alternative splicing and alternate signal peptide cleavage sites, multiple isoforms are known. FAM3B is expressed by pancreatic islet alpha and beta -cells, reproductive epithelium and a subset of neurons. Recombinant FAM3B has been shown to induce beta -cell apoptosis. The amino acid sequence of mature human FAM3B is 80% identical to that of mature mouse FAM3B.

Long Name

Family With Sequence Similarity 3, Member B

Alternate Names

PANDER, PRED44

Entrez Gene IDs

54097 (Human)

Gene Symbol

FAM3B

UniProt

NP_478066

Additional FAM3B Products

Product Documents for Human FAM3B Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human FAM3B Antibody

For research use only

Related Research Areas

Diabetes

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